Avner Yayon

Overview

Best Publications

• Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor.

  Avner Yayon;Michael Klagsbrun;Jeffrey D. Esko;Philip Leder

  3072
  Citations

• Crystal Structure of a Ternary FGF-FGFR-Heparin Complex Reveals a Dual Role for Heparin in FGFR Binding and Dimerization

  Joseph Schlessinger;Alexander N. Plotnikov;Omar A. Ibrahimi;Anna V. Eliseenkova

  1551
  Citations

• Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells.

  D M Ornitz;A Yayon;J G Flanagan;C M Svahn

  862
  Citations

• Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2).

  Avi Orr-Urtreger;Mark T. Bedford;Tatjana Burakova;Esther Arman

  782
  Citations

• Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

  David Aviezer;Dalit Hecht;Michal Safran;Magdalena Eisinger

  772
  Citations

• Complexity of FGF receptors: genetic basis for structural diversity and functional specificity.

  David Givol;Avner Yayon

  660
  Citations

• Developmental expression of two murine fibroblast growth factor receptors, flg and bek.

  A. Orr-Urtreger;D. Givol;A. Yayon;Y. Yarden

  569
  Citations

• Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1.

  Ehud Levi;Rafael Fridman;Hua Quan Miao;Yong Sheng Ma

  464
  Citations

• ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms.

  E Tzahar;G Levkowitz;D Karunagaran;L Yi

  379
  Citations

• Differential structural requirements of heparin and heparan-sulfate proteoglycans that promote binding of basic fibroblast growth-factor to its receptor

  D Aviezer;E Levy;M Safran;C Svahn

  377
  Citations

• Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity

  Shaun K. Olsen;Omar A. Ibrahimi;Angela Raucci;Fuming Zhang

  332
  Citations

• Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis

  Lin Chen;Rivka Adar;Xiao Yang;Efrat O. Monsonego

  298
  Citations

• Susceptibility of human malaria parasites to chloroquine is pH dependent.

  A Yayon;Z I Cabantchik;H Ginsburg

  275
  Citations

• Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor.

  Hwai-Loong Kong;Dalit Hecht;Wenru Song;Imre Kovesdi

  274
  Citations

• A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3

  Yingcai Wang;Michal K. Spatz;Karuppiah Kannan;Hovhannisyan Hayk

  260
  Citations

• Distinct fibroblast growth factor (FGF)/FGF receptor signaling pairs initiate diverse cellular responses in the oligodendrocyte lineage.

  Dale Fortin;Eran Rom;Haijun Sun;Avner Yayon

  222
  Citations

• Human Combinatorial Fab Library Yielding Specific and Functional Antibodies against the Human Fibroblast Growth Factor Receptor 3

  Robert Rauchenberger;Eric Borges;Elisabeth Thomassen-Wolf;Eran Rom

  216
  Citations

• A confined variable region confers ligand specificity on fibroblast growth factor receptors: implications for the origin of the immunoglobulin fold.

  A Yayon;Y Zimmer;Gh Shen;A Avivi

  213
  Citations

• Differential expression of the two VEGF receptors flt and KDR in placenta and vascular endothelial cells.

  Bernhard Barleon;Stefanie Hauser;Claudia Schöllmann;Karin Weindel

  201
  Citations

• The Transmembrane Mutation G380R in Fibroblast Growth Factor Receptor 3 Uncouples Ligand-Mediated Receptor Activation from Down-Regulation

  E. Monsonego-Ornan;R. Adar;T. Feferman;O. Segev

  198
  Citations