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Microbiology

D-Index
87
Citations
71791
World Ranking
773
National Ranking
361

Research.com Recognitions

  • 2012 - Fellow of the MacArthur Foundation

Overview

Sarkis K. Mazmanian is affiliated with the California Institute of Technology in the United States. Their research primarily covers Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Key subfields of study include Molecular Biology, Physiology, Neurology, Biological Psychiatry, and Cognitive Neuroscience.

The main research topics they have explored include:

  • Gut microbiota and health
  • Diet and metabolism studies
  • Tryptophan and brain disorders
  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Autism Spectrum Disorder Research

Their body of work spans several high-profile journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • eLife
  • Nature Neuroscience
  • SSRN Electronic Journal

Sarkis K. Mazmanian has contributed to numerous papers, including the following recent publications:

  • The gut microbiota-brain axis in behaviour and brain disorders, 2020, Nature Reviews Microbiology
  • Global chemical effects of the microbiome include new bile-acid conjugations, 2020, Nature
  • A gut-derived metabolite alters brain activity and anxiety behaviour in mice, 2022, Nature
  • A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice, 2020, eLife
  • Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice, 2020, Nature Neuroscience

Frequent co-authors in their work include:

  • Rob Knight
  • Brittany D. Needham
  • Viviana Gradinaru
  • Taren Thron
  • Joseph C. Boktor

The scientist was awarded the Fellowship of the MacArthur Foundation in 2012.

Best Publications

  • The gut microbiota shapes intestinal immune responses during health and disease

    June L. Round;Sarkis K. Mazmanian

  • Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

    Elaine Y. Hsiao;Sara W. McBride;Sophia Hsien;Gil Sharon

  • Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

    Timothy R. Sampson;Justine W. Debelius;Taren Thron;Stefan Janssen

  • Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

    Jessica M. Yano;Kristie Yu;Gregory P. Donaldson;Gauri G. Shastri

  • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system.

    Sarkis K. Mazmanian;Sarkis K. Mazmanian;Cui Hua Liu;Cui Hua Liu;Arthur O. Tzianabos;Arthur O. Tzianabos;Dennis L. Kasper;Dennis L. Kasper

  • Animals in a bacterial world, a new imperative for the life sciences

    Margaret McFall-Ngai;Michael G. Hadfield;Thomas C. G. Bosch;Hannah V. Carey

  • A microbial symbiosis factor prevents intestinal inflammatory disease

    Sarkis K. Mazmanian;June L. Round;Dennis L. Kasper;Dennis L. Kasper

  • Gut biogeography of the bacterial microbiota

    Gregory P. Donaldson;S. Melanie Lee;Sarkis K. Mazmanian

  • Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

    June L. Round;Sarkis K. Mazmanian

  • The gut microbiota-brain axis in behaviour and brain disorders.

    Livia H. Morais;Henry L. Schreiber;Sarkis K. Mazmanian

  • The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

    June L. Round;S. Melanie Lee;Jennifer Li;Gloria Tran

  • Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

    Ken Y. Chan;Min J. Jang;Bryan B. Yoo;Alon Greenbaum

  • The Central Nervous System and the Gut Microbiome

    Gil Sharon;Timothy R. Sampson;Daniel H. Geschwind;Sarkis K. Mazmanian

  • Has the Microbiota Played a Critical Role in the Evolution of the Adaptive Immune System

    Yun Kyung Lee;Sarkis K. Mazmanian

  • Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

    Yun Kyung Lee;Juscilene S. Menezes;Yoshinori Umesaki;Sarkis K. Mazmanian

  • Staphylococcus aureus Sortase, an Enzyme that Anchors Surface Proteins to the Cell Wall

    Sarkis K. Mazmanian;Gwen Liu;Hung Ton-That;Olaf Schneewind

  • Gut microbes and the brain: paradigm shift in neuroscience.

    Emeran A. Mayer;Rob Knight;Sarkis K. Mazmanian;John F. Cryan

  • Control of Brain Development, Function, and Behavior by the Microbiome

    Timothy R. Sampson;Sarkis K. Mazmanian

  • Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

    Gil Sharon;Nikki Jamie Cruz;Dae Wook Kang;Michael J. Gandal

  • Communicable Ulcerative Colitis Induced by T-bet Deficiency in the Innate Immune System

    Wendy S. Garrett;Graham M. Lord;Graham M. Lord;Graham M. Lord;Shivesh Punit;Geanncarlo Lugo-Villarino

Frequent Co-Authors

Rob Knight
Rob Knight University of California, San Diego
Olaf Schneewind
Olaf Schneewind University of Chicago
Paul H. Patterson
Paul H. Patterson California Institute of Technology
Patrizia Casaccia
Patrizia Casaccia City University of New York
Dennis L. Kasper
Dennis L. Kasper Harvard University
Hung Ton-That
Hung Ton-That University of California, Los Angeles
Pieter C. Dorrestein
Pieter C. Dorrestein University of California, San Diego
Sergio E. Baranzini
Sergio E. Baranzini University of California, San Francisco
Bruce A. C. Cree
Bruce A. C. Cree University of California, San Francisco
Viviana Gradinaru
Viviana Gradinaru California Institute of Technology

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