2012 - Fellow of the MacArthur Foundation
His primary areas of investigation include Microbiology, Immune system, Immunology, Bacteroides fragilis and Microbiome. His Microbiology research integrates issues from Mutant, Human microbiome, Commensalism, Allergic sensitization and Cell wall. T cell and FOXP3 are among the areas of Immune system where Sarkis K. Mazmanian concentrates his study.
His work in Immunology addresses subjects such as Inflammatory bowel disease, which are connected to disciplines such as Colitis. His research in Bacteroides fragilis focuses on subjects like Cytokine, which are connected to Bacterial polysaccharide, Symbiotic bacteria and Bacteria. In general Microbiome, his work in Gastrointestinal Microbiome is often linked to Interleukin 22 linking many areas of study.
His primary areas of study are Microbiology, Immunology, Immune system, Microbiome and Gut flora. His research in Microbiology intersects with topics in Mutant, Virulence and Bacteria. His Immunology research is multidisciplinary, incorporating elements of Gastrointestinal tract and Disease, Inflammatory bowel disease.
The study of Immune system is intertwined with the study of Host in a number of ways. In his research, Gastrointestinal Microbiome is intimately related to Neuroscience, which falls under the overarching field of Microbiome. His Bacteroides fragilis study deals with Cytokine intersecting with Inflammation.
His scientific interests lie mostly in Immunology, Microbiome, Gut flora, Immune system and Disease. His Immunology research is multidisciplinary, incorporating perspectives in Inflammatory bowel disease and Autism spectrum disorder. His work on Human microbiome and Gut–brain axis as part of general Microbiome research is frequently linked to Human spaceflight, bridging the gap between disciplines.
His work in Gut flora addresses issues such as Multiple sclerosis, which are connected to fields such as DNA methylation and Epigenetics. His work deals with themes such as Neuroscience, Human genetics and Microbiology, which intersect with Immune system. His biological study focuses on Bacteroides fragilis.
His primary areas of study are Microbiome, Immunology, Immune system, Gut flora and Gut–brain axis. He interconnects Gastrointestinal tract, IL-2 receptor and Metabolomics in the investigation of issues within Microbiome. The concepts of his Immunology study are interwoven with issues in Adaptation and Disease.
His Immune system study integrates concerns from other disciplines, such as Ontogeny and Bacteroides fragilis. His study on Bacteroides fragilis is covered under Microbiology. The various areas that he examines in his Gut flora study include Metabolome, Multiple sclerosis, FOXP3 and Autism spectrum disorder.
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The gut microbiota shapes intestinal immune responses during health and disease
June L. Round;Sarkis K. Mazmanian.
Nature Reviews Immunology (2009)
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system.
Sarkis K. Mazmanian;Sarkis K. Mazmanian;Cui Hua Liu;Cui Hua Liu;Arthur O. Tzianabos;Arthur O. Tzianabos;Dennis L. Kasper;Dennis L. Kasper.
Cell (2005)
Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
Elaine Y. Hsiao;Sara W. McBride;Sophia Hsien;Gil Sharon.
Cell (2013)
A microbial symbiosis factor prevents intestinal inflammatory disease
Sarkis K. Mazmanian;June L. Round;Dennis L. Kasper;Dennis L. Kasper.
Nature (2008)
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
Jessica M. Yano;Kristie Yu;Gregory P. Donaldson;Gauri G. Shastri.
Cell (2015)
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
Timothy R. Sampson;Justine W. Debelius;Taren Thron;Stefan Janssen.
Cell (2016)
Animals in a bacterial world, a new imperative for the life sciences
Margaret McFall-Ngai;Michael G. Hadfield;Thomas C. G. Bosch;Hannah V. Carey.
Proceedings of the National Academy of Sciences of the United States of America (2013)
Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
June L. Round;Sarkis K. Mazmanian.
Proceedings of the National Academy of Sciences of the United States of America (2010)
Gut biogeography of the bacterial microbiota
Gregory P. Donaldson;S. Melanie Lee;Sarkis K. Mazmanian.
Nature Reviews Microbiology (2016)
The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota
June L. Round;S. Melanie Lee;Jennifer Li;Gloria Tran.
Science (2011)
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