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Victor W.M. van Hinsbergh

Victor W.M. van Hinsbergh

D-Index & Metrics

Medicine

D-Index
102
Citations
34617
World Ranking
7721
National Ranking
300

Overview

Victor W.M. van Hinsbergh is affiliated with the University of Amsterdam in the Netherlands. Their research encompasses fields in Medicine and Biochemistry, Genetics and Molecular Biology, with specific subfields including Immunology and Allergy, Molecular Biology, Genetics, Cardiology and Cardiovascular Medicine, and Endocrinology, Diabetes and Metabolism.

The scientist's work covers a range of topics related to cell biology and disease mechanisms. Key research areas include:

  • Cell Adhesion Molecules Research
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Diabetes Treatment and Management
  • Pancreatic function and diabetes
  • Dialysis and Renal Disease Management
  • Protein Kinase Regulation and GTPase Signaling
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Several recent papers highlight the focus and scope of their research contributions:

  • Empagliflozin restores chronic kidney disease-induced impairment of endothelial regulation of cardiomyocyte relaxation and contraction (2020, Kidney International)
  • Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity (2020, Journal of Cell Science)
  • Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation (2021, Angiogenesis)
  • Perivascular Adipose Tissue Controls Insulin-Stimulated Perfusion, Mitochondrial Protein Expression, and Glucose Uptake in Muscle Through Adipomuscular Arterioles (2020, Diabetes)
  • Correction to: Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation (2021, Angiogenesis)

Their research has been published frequently in several scientific venues, prominently including:

  • Angiogenesis
  • Kidney International
  • Journal of Cell Science
  • Diabetes

Collaboration has been an important aspect of their work. Frequent coauthors include:

  • Etto C. Eringa
  • Peter L. Hordijk
  • Jurjan Aman
  • Joana Amado-Azevedo
  • Anne-Marieke D. van Stalborch

Best Publications

  • Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

    Arja Kaipainen;Jaana Korhonen;Tuija Mustonen;Victor W. M. van Hinsbergh

  • Role of IL-6 and Its Soluble Receptor in Induction of Chemokines and Leukocyte Recruitment

    Maria Romano;Marina Sironi;Carlo Toniatti;Nadia Polentarutti

  • Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead.

    Victor W M van Hinsbergh;Pieter Koolwijk

  • Polarized Vascular Endothelial Growth Factor Secretion by Human Retinal Pigment Epithelium and Localization of Vascular Endothelial Growth Factor Receptors on the Inner Choriocapillaris : Evidence for a Trophic Paracrine Relation

    Harriët G.T. Blaauwgeers;Gertjan M. Holtkamp;Hugo Rutten;Antonella N. Witmer

  • Endothelium--role in regulation of coagulation and inflammation.

    Victor W. M. van Hinsbergh

  • Endothelial dysfunction and pathogenesis of diabetic angiopathy

    Coen D.A Stehouwer;Jan Lambert;A.J.M Donker;Victor W.M van Hinsbergh

  • Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells - Regulation by tumor necrosis factor-alpha and doxycycline

    Roeland Hanemaaijer;Timo Sorsa;Yrjö T. Konttinen;Yanli Ding

  • Pericellular Proteases in Angiogenesis and Vasculogenesis

    Victor W.M. van Hinsbergh;Marten A. Engelse;Paul H.A. Quax

  • Activation of RhoA by Thrombin in Endothelial Hyperpermeability: Role of Rho Kinase and Protein Tyrosine Kinases

    G. P. Van Nieuw Amerongen;S. Van Delft;M. A. Vermeer;J. G. Collard

  • Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester.

    R Hanemaaijer;P Koolwijk;L le Clercq;W J A de Vree

  • Role of fibrin matrix in angiogenesis.

    Victor W.M. van Hinsbergh;Annemie Collen;Pieter Koolwijk

  • Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium

    V.W.M. van Hinsbergh;R.M. Bertina;A. van Wijngaarden;N.H. van Tilburg

  • Thin-walled microvessels in human coronary atherosclerotic plaques show incomplete endothelial junctions: relevance of compromised structural integrity for intraplaque microvascular leakage

    Judith C. Sluimer;Frank D. Kolodgie;Ann P.J.J. Bijnens;Kimberly Maxfield

  • Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity.

    Wineke Bakker;Etto C. Eringa;Pieter Sipkema;Victor W. M. van Hinsbergh

  • von Willebrand factor, C-reactive protein, and 5-year mortality in diabetic and nondiabetic subjects: the Hoorn Study.

    Agnes Jager;Victor W. M. van Hinsbergh;Piet J. Kostense;Jef J. Emeis

  • Plasma concentration of C-reactive protein is increased in Type I diabetic patients without clinical macroangiopathy and correlates with markers of endothelial dysfunction: evidence for chronic inflammation

    C. G. Schalkwijk;D. C. W. Poland;W. van Dijk;A. Kok

  • Endothelial Progenitors: A Consensus Statement on Nomenclature.

    Reinhold J. Medina;Chad L. Barber;Florence Sabatier;Francoise Dignat-George

  • Tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo

    V.W.M. van Hinsbergh;T. Kooistra;E.A. van den Berg;H.M.G. Princen

  • Tumor necrosis factor and interleukin-1 induce expression of the verocytotoxin receptor globotriaosylceramide on human endothelial cells: implications for the pathogenesis of the hemolytic uremic syndrome.

    N. C. A. J. Van De Kar;L. A. H. Monnens;M. A. Karmali;V. W. M. Van Hinsbergh

  • Cooperative effect of TNFalpha, bFGF, and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix. Role of urokinase activity.

    P. Koolwijk;M. G. M. Van Erck;W. J. A. De Vree;M. A. Vermeer

Frequent Co-Authors

Paul H.A. Quax
Paul H.A. Quax Leiden University Medical Center
Coen D.A. Stehouwer
Coen D.A. Stehouwer Maastricht University
Casper G. Schalkwijk
Casper G. Schalkwijk Maastricht University
John S Yudkin
John S Yudkin University College London
Lex M. Bouter
Lex M. Bouter Vrije Universiteit Amsterdam
Jacqueline M. Dekker
Jacqueline M. Dekker VU University Medical Center
Hans M.G. Princen
Hans M.G. Princen Netherlands Organisation for Applied Scientific Research
Clemens W.G.M. Löwik
Clemens W.G.M. Löwik Erasmus University Rotterdam
Robert J. Heine
Robert J. Heine VU University Medical Center
Giel Nijpels
Giel Nijpels VU University Medical Center

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