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Biology and Biochemistry

D-Index
75
Citations
22003
World Ranking
5274
National Ranking
129

Overview

Ko Willems van Dijk is affiliated with Leiden University Medical Center in the Netherlands. Their research spans across Medicine and Biochemistry, Genetics and Molecular Biology, with a substantial focus on molecular biology, genetics, physiology, epidemiology, and endocrinology, diabetes, and metabolism.

Their recent scientific contributions include the following publications:

  • Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles, 2022, Nature Genetics
  • Genome-wide characterization of circulating metabolic biomarkers, 2024, Nature
  • The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies, 2020, Diabetology & Metabolic Syndrome
  • Heritability estimates for 361 blood metabolites across 40 genome-wide association studies, 2020, Nature Communications
  • Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas, 2020, Nature Medicine

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Atherosclerosis
  • Nutrition Metabolism and Cardiovascular Diseases
  • UNC Libraries
  • Annals of Neurology

Ko Willems van Dijk collaborates regularly with several researchers, including:

  • Raymond Noordam
  • Diana van Heemst
  • Frits R. Rosendaal
  • J. Wouter Jukema
  • Renée de Mutsert

Their main research fields are Medicine with 175 publications and Biochemistry, Genetics and Molecular Biology with 120 publications. Key subfields include molecular biology, genetics, physiology, epidemiology, and endocrinology, diabetes, and metabolism.

The primary topics covered in their work consist of:

  • Genetic Associations and Epidemiology
  • Metabolomics and Mass Spectrometry Studies
  • Diet and metabolism studies
  • Liver Disease Diagnosis and Treatment
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases

Best Publications

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

    Johannes Kettunen;Ayşe Demirkan;Ayşe Demirkan;Peter Würtz;Harmen H M Draisma

  • Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit

    Zhuang Li;Chun-Xia Yi;Saeed Katiraei;Sander Kooijman

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Felix R. Day;Deborah J. Thompson;Hannes Helgason;Hannes Helgason;Daniel I. Chasman

  • Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

    Z Dastani;Hivert M-F.;Hivert M-F.;N Timpson;Perry Jrb.;Perry Jrb.

  • Meta-analysis of genome-wide association studies in >80,000 subjects identifies multiple loci for C-reactive protein levels

    Abbas Dehghan;Josée Dupuis;Josée Dupuis;Maja Barbalic;Joshua C. Bis

  • Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    Louise V. Wain;Germaine C. Verwoert;Paul F. O'Reilly;Gang Shi

  • Body fat distribution, in particular visceral fat, is associated with cardiometabolic risk factors in obese women.

    Theodora W. Elffers;Renée de Mutsert;Hildo J. Lamb;Albert de Roos

  • ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis.

    Frank G. Schaap;Patrick C.N. Rensen;Peter J. Voshol;Carlos Vrins

  • The expression of type III hyperlipoproteinemia: involvement of lipolysis genes

    Peter Henneman;Femke Van Der Sman-De Beer;Payman Hanifi Moghaddam;Petra Huijts

  • Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping

    Paula J P de Vree;Elzo de Wit;Mehmet Yilmaz;Monique van de Heijning

  • Detrimental effects of constant light exposure and high-fat diet on circadian energy metabolism and insulin sensitivity

    Claudia P. Coomans;Sjoerd A. A. van den Berg;Thijs Houben;Jan-Bert van Klinken

  • Genetic insights into biological mechanisms governing human ovarian ageing.

    Katherine S. Ruth;Felix R. Day;Jazib Hussain;Ana Martínez-Marchal

  • Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice

    Leonie Hussaarts;Noemí García-Tardón;Lianne van Beek;Mattijs M. Heemskerk

  • Angptl4 Upregulates Cholesterol Synthesis in Liver via Inhibition of LPL- and HL-Dependent Hepatic Cholesterol Uptake

    Laeticia Lichtenstein;Jimmy F.P. Berbée;Susan J. van Dijk;Ko Willems van Dijk

  • Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

    Harmen H. M. Draisma;Harmen H. M. Draisma;René Pool;René Pool;Michael Kobl;Rick Jansen

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

  • Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan A;Spracklen Cn;Zhang W;Ng Mc

  • Meta-Analysis of Genome-Wide Association Studies in > 80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels

    Abbas Dehghan;Josee Dupuis;Maja Barbalic;Joshua C. Bis

Frequent Co-Authors

Patrick C. N. Rensen
Patrick C. N. Rensen Leiden University Medical Center
Louis M. Havekes
Louis M. Havekes Leiden University Medical Center
Dennis O. Mook-Kanamori
Dennis O. Mook-Kanamori Leiden University Medical Center
Ayse Demirkan
Ayse Demirkan University of Surrey
Frits R. Rosendaal
Frits R. Rosendaal Leiden University Medical Center
J. Wouter Jukema
J. Wouter Jukema Leiden University Medical Center
Gonneke Willemsen
Gonneke Willemsen Vrije Universiteit Amsterdam
Diana van Heemst
Diana van Heemst Leiden University Medical Center
P. Eline Slagboom
P. Eline Slagboom Leiden University Medical Center
Najaf Amin
Najaf Amin University of Oxford

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