Richard U. Margolis

Overview

Best Publications

• The chondroitin sulfate proteoglycans neurocan, brevican, phosphacan, and versican are differentially regulated following spinal cord injury.

  Leonard L Jones;Richard U Margolis;Mark H Tuszynski;Mark H Tuszynski

  693
  Citations

• The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth

  David R. Friedlander;Peter Milev;Laina Karthikeyan;Renée K. Margolis

  665
  Citations

• Neurocan is upregulated in injured brain and in cytokine-treated astrocytes.

  Richard A. Asher;Daniel A. Morgenstern;Penny S. Fidler;Kathryn H. Adcock

  618
  Citations

• Cloning and primary structure of neurocan, a developmentally regulated, aggregating chondroitin sulfate proteoglycan of brain.

  Uwe Rauch;Laina Karthikeyan;Patrice Maurel;Richard U. Margolis

  494
  Citations

• Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules.

  P Milev;D R Friedlander;T Sakurai;L Karthikeyan

  486
  Citations

• Phosphacan, a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell-adhesion molecules, is an extracellular variant of a receptor-type protein tyrosine phosphatase

  Patrice Maurel;Uwe Rauch;Manuela Flad;Renee K. Margolis

  423
  Citations

• Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity.

  Hiroshi Manya;Atsuro Chiba;Aruto Yoshida;Xiaohui Wang

  413
  Citations

• Fibrinogen Triggers Astrocyte Scar Formation by Promoting the Availability of Active TGF-β after Vascular Damage

  Christian Schachtrup;Jae K. Ryu;Matthew J. Helmrick;Eirini Vagena

  409
  Citations

• Functional Characterization of Chondroitin Sulfate Proteoglycans of Brain: Interactions with Neurons and Neural Cell Adhesion Molecules

  Martin Grumet;Andrea Flaccus;Richard U. Margolis

  395
  Citations

• Isolation and characterization of developmentally regulated chondroitin sulfate and chondroitin/keratan sulfate proteoglycans of brain identified with monoclonal antibodies.

  U Rauch;P Gao;A Janetzko;A Flaccus

  389
  Citations

• Insulin in the Cerebrospinal Fluid

  Richard U. Margolis;Norman Altszuler

  374
  Citations

• Interactions with tenascin and differential effects on cell adhesion of neurocan and phosphacan, two major chondroitin sulfate proteoglycans of nervous tissue.

  Martin Grumet;Peter Milev;Takeshi Sakurai;Laina Karthikeyan

  372
  Citations

• Postnatal development of perineuronal nets in wild-type mice and in a mutant deficient in tenascin-R.

  Gert Brückner;Jens Grosche;Sandra Schmidt;Wolfgang Härtig

  363
  Citations

• Glycosaminoglycans of brain during development.

  R U Margolis;R K Margolis;L B Chang;C Preti

  341
  Citations

• TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/protein-tyrosine phosphatase-ζ/β, and N-CAM

  Peter Milev;Patrice Maurel;Monika Häring;Renée K. Margolis

  304
  Citations

• Differential regulation of expression of hyaluronan-binding proteoglycans in developing brain: aggrecan, versican, neurocan, and brevican.

  Peter Milev;Patrice Maurel;Atsuro Chiba;Markus Mevissen

  303
  Citations

• High Affinity Binding and Overlapping Localization of Neurocan and Phosphacan/Protein-tyrosine Phosphatase-ζ/β with Tenascin-R, Amphoterin, and the Heparin-binding Growth-associated Molecule

  Peter Milev;Atsuro Chiba;Monika Häring;Heikki Rauvala

  302
  Citations

• Localization of epidermal hyaluronic acid using the hyaluronate binding region of cartilage proteoglycan as a specific probe

  Raija. Tammi;James A. Ripellino;Richard U. Margolis;Markku. Tammi

  300
  Citations

• Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.

  P Weber;U Bartsch;U Bartsch;M N Rasband;R Czaniera

  293
  Citations

• Chondroitin sulfate proteoglycans as mediators of axon growth and pathfinding

  Richard U. Margolis;Renée K. Margolis

  245
  Citations