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D-Index & Metrics

Medicine

D-Index
113
Citations
236569
World Ranking
4807
National Ranking
62

Research.com Recognitions

  • 2009 - Member of the National Academy of Sciences
  • 2008 - Member of the National Academy of Medicine (NAM)
  • 2007 - Fellow of the American Academy of Arts and Sciences
  • 1971 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Douglas Hanahan is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research primarily spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these broad areas, their subfields of study include Immunology, Oncology, Molecular Biology, Cancer Research, and Physiology.

Their work covers multiple topics related to cancer and the immune system. These include:

  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Cancer, Stress, Anesthesia, and Immune Response
  • CAR-T cell therapy research
  • Cancer Genomics and Diagnostics
  • Cancer, Hypoxia, and Metabolism

Hanahan has contributed to notable papers such as:

  • "Cancer hallmarks intersect with neuroscience in the tumor microenvironment," published in 2023 in Cancer Cell
  • "Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages," 2023, Immunity
  • "PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells," 2022, Nature

While some influential papers in related fields are authored by other researchers, their intersectional relevance includes works like "Embracing cancer complexity: Hallmarks of systemic disease," 2024, Cell, and "Roadmap for the Emerging Field of Cancer Neuroscience," 2020, Cell.

Frequent coauthors working alongside Hanahan include:

  • Mélanie Tichet
  • Agnieszka Chryplewicz
  • Krisztián Homicskó
  • Stephan Wullschleger
  • Nadine Fournier

Their research has been published often in high-impact journals, with frequent publication venues including:

  • Cancer Cell
  • Cancer Discovery
  • Cancer Research
  • Cell
  • Molecular Oncology

Douglas Hanahan's career has been recognized through several awards and memberships in prestigious academies. These include:

  • Member of the National Academy of Sciences (2009)
  • Member of the National Academy of Medicine (NAM) (2008)
  • Fellow of the American Academy of Arts and Sciences (2007)
  • Fellow of the American Association for the Advancement of Science (AAAS) (1971)

Best Publications

  • Hallmarks of cancer: the next generation.

    Douglas Hanahan;Robert A. Weinberg

  • The hallmarks of cancer.

    Douglas Hanahan;Robert A Weinberg

  • Studies on transformation of Escherichia coli with plasmids

    Douglas Hanahan;Douglas Hanahan

  • Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

    Douglas Hanahan;Judah Folkman;Judah Folkman

  • Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

    Douglas Hanahan;Lisa M. Coussens

  • The consensus molecular subtypes of colorectal cancer

    Justin Guinney;Rodrigo Dienstmann;Rodrigo Dienstmann;Xingwu Wang;Xingwu Wang;Aurélien De Reyniès

  • Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

    Gabriele Bergers;Rolf Brekken;Gerald McMahon;Thiennu H. Vu

  • Induction of angiogenesis during the transition from hyperplasia to neoplasia

    Judah Folkman;Karol Watson;Donald Ingber;Douglas Hanahan;Douglas Hanahan

  • Heritable formation of pancreatic β -cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

    Douglas Hanahan

  • MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

    Thiennu H Vu;J.Michael Shipley;Gabriele Bergers;Joel E Berger

  • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

    Oriol Casanovas;Daniel J. Hicklin;Gabriele Bergers;Douglas Hanahan

  • Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy.

    Eric A Collisson;Anguraj Sadanandam;Anguraj Sadanandam;Peter Olson;Peter Olson;William J Gibb;William J Gibb

  • MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

    Lisa M Coussens;Christopher L Tinkle;Douglas Hanahan;Zena Werb

  • Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants.

    Seth G. N. Grant;Joel Jessee;Fredric R. Bloom;Douglas Hanahan

  • Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice

    Gabriele Bergers;Kashi Javaherian;Kin-Ming Lo;Judah Folkman

  • Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis

    Hiroaki Nozawa;Christopher Chiu;Douglas Hanahan

  • Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

    Lisa M. Coussens;Wilfred W. Raymond;Gabriele Bergers;Marion Laig-Webster

  • A colorectal cancer classification system that associates cellular phenotype and responses to therapy

    Anguraj Sadanandam;Costas A Lyssiotis;Costas A Lyssiotis;Krisztian Homicsko;Krisztian Homicsko;Eric A Collisson

  • Plasmid transformation of Escherichia coli and other bacteria

    Douglas Hanahan;Joel Jessee;Fredric R. Bloom

  • Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis

    Johanna A. Joyce;Amos Baruch;Amos Baruch;Kareem Chehade;Kareem Chehade;Nicole Meyer-Morse

Frequent Co-Authors

Judah Folkman
Judah Folkman Boston Children's Hospital
Gerard I. Evan
Gerard I. Evan The Francis Crick Institute
Giovanni Ciriello
Giovanni Ciriello University of Lausanne
Joe W. Gray
Joe W. Gray Oregon Health & Science University
Seth G. N. Grant
Seth G. N. Grant University of Edinburgh
Michael Wigler
Michael Wigler Cold Spring Harbor Laboratory
J.M. Polak
J.M. Polak Hammersmith Hospital
Victoria L. Bautch
Victoria L. Bautch University of North Carolina at Chapel Hill
Lisa M. Coussens
Lisa M. Coussens Oregon Health & Science University

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