World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
14206
World Ranking
7164
National Ranking
3286

Overview

Gary Rudnick is affiliated with Yale University in the United States and contributes primarily to the fields of Biochemistry, Genetics and Molecular Biology as well as Neuroscience. Their research spans several subfields including Cellular and Molecular Neuroscience, Molecular Biology, Spectroscopy, Biochemistry, and Astronomy and Astrophysics.

Their recent publications cover a range of topics in neuroscience and molecular biology, highlighting investigations into serotonin transporters, glycine transporters, and ion binding sites. Notable papers include:

  • Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning (2020, Cell)
  • Structure-based discovery of conformationally selective inhibitors of the serotonin transporter (2023, Cell)
  • Satellite quenching was not important for z ∼ 1 clusters: most quenching occurred during infall (2021, Monthly Notices of the Royal Astronomical Society)
  • Chloride-dependent conformational changes in the GlyT1 glycine transporter (2021, Proceedings of the National Academy of Sciences)
  • Identification of the potassium-binding site in serotonin transporter (2024, Proceedings of the National Academy of Sciences)

Their research largely covers topics related to Neuroscience and Neuropharmacology Research, Receptor Mechanisms and Signaling, Neurotransmitter Receptor Influence on Behavior, Analytical Chemistry and Chromatography, Amino Acid Enzymes and Metabolism, Ion channel regulation and function, and Molecular Sensors and Ion Detection.

Gary Rudnick collaborates frequently with several researchers including Yuan-Wei Zhang, Walter Sandtner, Bethlehem Bekele, Danila Boytsov, and Lucy R. Forrest.

Their work is published predominantly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Cell, Proceedings of the National Academy of Sciences, and IUPHAR/BPS Guide to Pharmacology CITE.

Best Publications

  • The molecular mechanism of "ecstasy" [3,4-methylenedioxy-methamphetamine (MDMA)]: serotonin transporters are targets for MDMA-induced serotonin release.

    Gary Rudnick;Stephen C. Wall

  • Serotonin transporter: gene, genetic disorders, and pharmacogenetics.

    Dennis L. Murphy;Alicja Lerner;Gary Rudnick;Klaus-Peter Lesch

  • From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters

    Gary Rudnick;Janet Clark

  • Stable expression of biogenic amine transporters reveals differences in inhibitor sensitivity, kinetics, and ion dependence.

    H Gu;S C Wall;G Rudnick

  • Acidification of macrophage and fibroblast endocytic vesicles in vitro.

    Cynthia J. Galloway;Gary E. Dean;Mark Marsh;Gary Rudnick

  • Mechanism for alternating access in neurotransmitter transporters

    Lucy R. Forrest;Yuan-Wei Zhang;Miriam T. Jacobs;Joan Gesmonde

  • The rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters.

    Lucy R. Forrest;Gary Rudnick

  • Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype

    N Ozaki;D Goldman;W H Kaye;K Plotnicov

  • Active transport of 5-hydroxytryptamine by plasma membrane vesicles isolated from human blood platelets.

    G Rudnick

  • Oligomerization of serotonin transporter and its functional consequences

    Fusun Kilic;Gary Rudnick

  • Identification of a chloride ion binding site in Na+/Cl−-dependent transporters

    Lucy R Forrest;Sotiria Tavoulari;Yuan-Wei Zhang;Gary Rudnick

  • Biogenic amine flux mediated by cloned transporters stably expressed in cultured cell lines: amphetamine specificity for inhibition and efflux.

    S C Wall;H Gu;G Rudnick

  • The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding

    Jie-Guang Chen;Aristidis Sachpatzidis;Gary Rudnick

  • Permeation and gating residues in serotonin transporter

    Jie-Guang Chen;Gary Rudnick

  • ATP-Driven H+ Pumping into Intracellular Organelles

    Gary Rudnick

  • Expression of a cloned gamma-aminobutyric acid transporter in mammalian cells.

    Shoshi Keynan;Young Jin Suh;Baruch I. Kanner;Gary Rudnick

  • EXTERNAL CYSTEINE RESIDUES IN THE SEROTONIN TRANSPORTER

    Jie-Guang Chen;Shuxian Liu-Chen;Gary Rudnick

  • Coupling between platelet 5-hydroxytryptamine and potassium transport.

    P J Nelson;G Rudnick

  • Determination of External Loop Topology in the Serotonin Transporter by Site-directed Chemical Labeling

    Jie-Guang Chen;Shuxian Liu-Chen;Gary Rudnick

  • Vaccinia-T7 RNA polymerase expression system: evaluation for the expression cloning of plasma membrane transporters.

    Randy D. Blakely;Janet A. Clark;Gary Rudnick;Susan G. Amara

Frequent Co-Authors

Harald H. Sitte
Harald H. Sitte Medical University of Vienna
Benjamin D. Greenberg
Benjamin D. Greenberg Brown University
Michael J. Caplan
Michael J. Caplan Yale University
Randy D. Blakely
Randy D. Blakely Florida Atlantic University
Michael Freissmuth
Michael Freissmuth Medical University of Vienna
Dennis L. Murphy
Dennis L. Murphy National Institutes of Health
Barry Honig
Barry Honig Columbia University
Stefan Boehm
Stefan Boehm Medical University of Vienna
Elizabeth Rhoades
Elizabeth Rhoades University of Pennsylvania
Veronica A. Alvarez
Veronica A. Alvarez National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Gary Rudnick

Trending Scientists