World's Best Scientists 2026 revealed!
Carol A. de la Motte

Carol A. de la Motte

Overview

Carol A. de la Motte is affiliated with the Cleveland Clinic in the United States. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with additional contributions in related subfields including Molecular Biology, Cell Biology, Immunology, Genetics, and Pathology and Forensic Medicine.

The scientist's work spans several main topics within biomedical research. These include:

  • Proteoglycans and glycosaminoglycans research
  • Fibroblast Growth Factor Research
  • Glycosylation and Glycoproteins Research
  • Galectins and Cancer Biology
  • Inflammatory Bowel Disease
  • Genetic factors in colorectal cancer

Carol A. de la Motte has published research in recognized scientific journals, contributing notably to:

  • Frontiers in Immunology
  • Scientific Reports

Two recent papers exemplify this work:

  • "The Role of Hyaluronan Treatment in Intestinal Innate Host Defense," published in 2020 in Frontiers in Immunology
  • "Human intelectin-1 (ITLN1) genetic variation and intestinal expression," published in 2021 in Scientific Reports

Throughout their publications, they have frequently collaborated with researchers including Yeojung Kim, Eric B. Nonnecke, Patricia A. Castillo, Amanda Dugan, and Faisal Almalki.

Best Publications

  • Hyaluronan, a crucial regulator of inflammation.

    Aaron C. Petrey;Carol A. de la Motte

  • Angiogenesis as a novel component of inflammatory bowel disease pathogenesis

    Silvio Danese;Miquel Sans;Carol de la Motte;Cristina Graziani

  • Mononuclear Leukocytes Bind to Specific Hyaluronan Structures on Colon Mucosal Smooth Muscle Cells Treated with Polyinosinic Acid:Polycytidylic Acid : Inter-α-Trypsin Inhibitor Is Crucial to Structure and Function

    Carol A. de la Motte;Vincent C. Hascall;Judith Drazba;Sudip K. Bandyopadhyay

  • Hyaluronan cross-linking: a protective mechanism in inflammation?

    Anthony J. Day;Carol A. de la Motte

  • The Toll–Interleukin-1 Receptor Member SIGIRR Regulates Colonic Epithelial Homeostasis, Inflammation, and Tumorigenesis

    Hui Xiao;Muhammet Fatih Gulen;Muhammet Fatih Gulen;Jinzhong Qin;Jinzhong Qin;Jianhong Yao

  • Inflammation-induced endothelial-to-mesenchymal transition: a novel mechanism of intestinal fibrosis.

    Florian Rieder;Sean P. Kessler;Gail A. West;Shardul Bhilocha

  • Platelets in inflammatory bowel disease: clinical, pathogenic, and therapeutic implications.

    Silvio Danese;Carol de la Motte;Claudio Fiocchi

  • Intracellular hyaluronan: a new frontier for inflammation?

    Vincent C Hascall;Alana K Majors;Carol A De La Motte;Stephen P Evanko

  • Mononuclear Leukocytes Preferentially Bind via CD44 to Hyaluronan on Human Intestinal Mucosal Smooth Muscle Cells after Virus Infection or Treatment with Poly(I·C)

    Carol A. de la Motte;Vincent C. Hascall;Anthony Calabro;Belinda Yen-Lieberman

  • Platelets trigger a CD40-dependent inflammatory response in the microvasculature of inflammatory bowel disease patients

    Silvio Danese;Carol de la Motte;Andreas Sturm;Jon D Vogel

  • Cutting edge: T cells trigger CD40-dependent platelet activation and granular RANTES release: a novel pathway for immune response amplification.

    Silvio Danese;Carol A De La Motte;Brenda M. Rivera Reyes;Miquel Sans

  • Endoplasmic Reticulum Stress Induces Hyaluronan Deposition and Leukocyte Adhesion

    Alana K. Majors;Richard C. Austin;Carol A. de la Motte;Reed E. Pyeritz

  • Angiogenesis blockade as a new therapeutic approach to experimental colitis

    Silvio Danese;Miquel Sans;David M Spencer;Ivy Beck

  • Central role of double-stranded RNA-activated protein kinase in microbial induction of nitric oxide synthase.

    Kohsaku Uetani;Sandy D. Der;Maryam Zamanian-Daryoush;Carol de la Motte

  • Primary Murine Airway Smooth Muscle Cells Exposed to Poly(I,C) or Tunicamycin Synthesize a Leukocyte-adhesive Hyaluronan Matrix

    Mark E. Lauer;Durba Mukhopadhyay;Csaba Fulop;Carol A. de la Motte

  • CD40-mediated immune-nonimmune cell interactions induce mucosal fibroblast chemokines leading to T-cell transmigration.

    Jon D. Vogel;Gail A. West;Silvio Danese;Carol de la Motte

  • Specific-sized Hyaluronan Fragments Promote Expression of Human β-Defensin 2 in Intestinal Epithelium

    David R. Hill;Sean P. Kessler;Hyunjin K. Rho;Mary K. Cowman

  • Hyaluronan (HA) deposition precedes and promotes leukocyte recruitment in intestinal inflammation.

    Sean Kessler;Hyunjin Rho;Gail West;Claudio Fiocchi

  • Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage.

    Peter Dy;Patrick Smits;Amber Silvester;Alfredo Penzo-Méndez

  • High levels of hyaluronan in idiopathic pulmonary arterial hypertension.

    Metin Aytekin;Suzy A. A. Comhair;Carol de la Motte;Sudip K. Bandyopadhyay

Frequent Co-Authors

Vincent C. Hascall
Vincent C. Hascall Cleveland Clinic
Claudio Fiocchi
Claudio Fiocchi Cleveland Clinic Lerner College of Medicine
Thomas N. Wight
Thomas N. Wight Virginia Mason Medical Center
Paul L. Fox
Paul L. Fox Cleveland Clinic Lerner College of Medicine
Anthony J. Day
Anthony J. Day University of Manchester
Richard C. Austin
Richard C. Austin McMaster University
Fu-Tong Liu
Fu-Tong Liu Academia Sinica
Serpil C. Erzurum
Serpil C. Erzurum Cleveland Clinic Lerner College of Medicine
Lynn Y. Sakai
Lynn Y. Sakai Oregon Health & Science University
Jacqueline T. Hecht
Jacqueline T. Hecht The University of Texas Health Science Center at Houston

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in expanding their knowledge beyond Immunology, pursuing related healthcare degrees online offers diverse career opportunities. Many students seek programs that balance quality education with accessibility. For example, those exploring nursing careers might consider programs known for being more accessible, such as which LPN programs are easiest to get into. These can provide a solid foundation for patient care roles in various clinical settings.

Nursing professionals aiming to advance their expertise often look into nurse practitioner degrees. Identifying the easiest nurse practitioner degree programs can help streamline the path to higher qualifications without compromising educational standards. This is especially useful for those balancing work, study, and personal commitments.

Specializing in mental health is becoming increasingly important, and psychiatric mental health nurse practitioner (PMHNP) programs are highly sought after. When choosing an online PMHNP program, it's crucial to consider clinical placement opportunities, which affect hands-on training quality. Students can explore the PMHNP programs online with best clinical placement to ensure practical experience aligns with educational goals.

Cost is another key factor for many learners. Fortunately, there are cheapest online PMHNP certificate programs available that offer affordable routes into this specialized field without sacrificing essential training. These options open doors to impactful careers in mental health and immunology-related disciplines.

Best Scientists Citing Carol A. de la Motte

Trending Scientists

Recently Published Articles