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D-Index & Metrics

Immunology

D-Index
57
Citations
14763
World Ranking
3589
National Ranking
1662

Overview

Claudio Fiocchi is affiliated with the Cleveland Clinic Lerner College of Medicine in the United States. Their research primarily focuses on medicine and biochemistry, genetics, and molecular biology, with 62 and 45 publications respectively in these fields.

The main subfields of Claudio Fiocchi's work include genetics, molecular biology, epidemiology, surgery, and oncology. Their scientific contributions span across multiple topics, with a strong emphasis on inflammatory bowel disease, microscopic colitis, gut microbiota and health, and the use of single-cell and spatial transcriptomics techniques. Other notable topics covered in their research are IL-33, ST2, and ILC pathways, celiac disease research and management, and Helicobacter pylori-related gastroenterology studies.

Claudio Fiocchi has published extensively in prominent journals. Frequent publication venues include:

  • Gastroenterology (20 publications)
  • Inflammatory Bowel Diseases (7 publications)
  • Gut (4 publications)
  • Journal of Crohn's and Colitis (4 publications)
  • International Journal of Molecular Sciences (2 publications)

Recent notable papers authored or co-authored by Claudio Fiocchi are:

  • Breaking the therapeutic ceiling in drug development in ulcerative colitis, 2021, The Lancet. Gastroenterology & Hepatology
  • A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19, 2020, PLoS Biology
  • Fibrosis in IBD: from pathogenesis to therapeutic targets, 2024, Gut
  • Activated intestinal muscle cells promote preadipocyte migration: a novel mechanism for creeping fat formation in Crohn's disease, 2021, Gut
  • Stricturing Crohn's Disease Single-Cell RNA Sequencing Reveals Fibroblast Heterogeneity and Intercellular Interactions, 2023, Gastroenterology

Claudio Fiocchi collaborates frequently with a range of co-authors, reflecting interdisciplinary and team-based research efforts. Frequent collaborators include Florian Rieder, Gail West, Sinan Lin, Pranab K. Mukherjee, and Ren Mao. These partnerships are often evident in joint publications related to inflammatory bowel disease and related gastrointestinal research.

Best Publications

  • Inflammatory bowel disease: Etiology and pathogenesis

    Claudio Fiocchi

  • Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation.

    Vincenzo Casini-Raggi;Lori Kam;Yoo Jin T Chong;Claudio Fiocchi

  • Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance

    Kenji Ina;Jugoh Itoh;Kouhei Fukushima;Kazuo Kusugami

  • Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis.

    Luca Pastorelli;Rekha R. Garg;Sharon B. Hoang;Luisa Spina

  • Ulcerative colitis and Crohn’s disease: distinctive gene expression profiles and novel susceptibility candidate genes

    Ian C. Lawrance;Claudio Fiocchi;Shukti Chakravarti

  • Angiogenesis as a novel component of inflammatory bowel disease pathogenesis

    Silvio Danese;Miquel Sans;Carol de la Motte;Cristina Graziani

  • VEGF-A Links Angiogenesis and Inflammation in Inflammatory Bowel Disease Pathogenesis

    Franco Scaldaferri;Stefania Vetrano;Miquel Sans;Vincenzo Arena

  • Platelets in inflammatory bowel disease: clinical, pathogenic, and therapeutic implications.

    Silvio Danese;Carol de la Motte;Claudio Fiocchi

  • Activated platelets are the source of elevated levels of soluble CD40 ligand in the circulation of inflammatory bowel disease patients

    Silvio Danese;Jeffry Katz;Simone Saibeni;Alfredo Papa

  • The emergence of inflammatory bowel disease in the Asian Pacific region

    Qin Ouyang;Rakesh Tandon;Khean Lee Goh;Choon Jin Ooi

  • Intestinal inflammation: a complex interplay of immune and nonimmune cell interactions

    Claudio Fiocchi

  • A murine model of Chronic inflammation-induced intestinal fibrosis down-regulated by antisense NF-κB

    Ian C Lawrance;Feng Wu;AndrÉ Z.A Leite;Joseph Willis

  • Enhanced leukocyte binding by intestinal microvascular endothelial cells in inflammatory bowel disease.

    DG Binion;GA West;K Ina;NP Ziats

  • Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease

    S Kugathasan;L J Saubermann;L Smith;D Kou

  • VEGF-C–dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease

    Silvia D’Alessio;Carmen Correale;Carlotta Tacconi;Alessandro Gandelli

  • Platelets trigger a CD40-dependent inflammatory response in the microvasculature of inflammatory bowel disease patients

    Silvio Danese;Carol de la Motte;Andreas Sturm;Jon D Vogel

  • Cutting edge: T cells trigger CD40-dependent platelet activation and granular RANTES release: a novel pathway for immune response amplification.

    Silvio Danese;Carol A De La Motte;Brenda M. Rivera Reyes;Miquel Sans

  • Inflammatory Bowel Disease: Autoimmune or Immune-mediated Pathogenesis?

    Zhonghui Wen;Claudio Fiocchi

  • TNF-α Blockade Down-Regulates the CD40/CD40L Pathway in the Mucosal Microcirculation: A Novel Anti-Inflammatory Mechanism of Infliximab in Crohn’s Disease

    Silvio Danese;Miquel Sans;Franco Scaldaferri;Alessandro Sgambato

  • The CD40/CD40L costimulatory pathway in inflammatory bowel disease

    S. Danese;M. Sans;Claudio Fiocchi

  • Critical role of the CD40–CD40-ligand pathway in regulating mucosal inflammation-driven angiogenesis in inflammatory bowel disease

    Silvio Danese;F. Scaldaferri;S. Vetrano;T. Stefanelli

Frequent Co-Authors

Silvio Danese
Silvio Danese Vita-Salute San Raffaele University
Carol A. de la Motte
Carol A. de la Motte Cleveland Clinic
Subra Kugathasan
Subra Kugathasan Emory University
Rocio Lopez
Rocio Lopez Cleveland Clinic
John R. Goldblum
John R. Goldblum Cleveland Clinic
Gary W. Falk
Gary W. Falk University of Pennsylvania
Richard H. Duerr
Richard H. Duerr University of Pittsburgh
Gerhard Rogler
Gerhard Rogler University of Zurich
Charalabos Pothoulakis
Charalabos Pothoulakis University of California, Los Angeles
Pranab K. Mukherjee
Pranab K. Mukherjee Louisiana State University

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