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Immunology

D-Index
83
Citations
32095
World Ranking
1420
National Ranking
724

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Raphaela Goldbach-Mansky is affiliated with the National Institute of Allergy and Infectious Diseases in the United States. Their research spans multiple fields within medicine, focusing particularly on immunology, molecular biology, and rheumatology. They have contributed extensively to the study of inflammasome and immune disorders, interferon and immune responses, and autoimmune and inflammatory disorders.

The primary fields of study for Goldbach-Mansky include Medicine with 102 publications, Biochemistry, Genetics and Molecular Biology with 66 publications, and Immunology and Microbiology with 54 publications. These are further refined into subfields such as Immunology, Molecular Biology, Rheumatology, Hematology, and Infectious Diseases.

Their recent publications include the following works:

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19, 2020, Science
  • An immune-based biomarker signature is associated with mortality in COVID-19 patients, 2020, JCI Insight
  • Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19, 2022, Nature Medicine
  • Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE, 2021, Cell
  • The 2021 EULAR/American College of Rheumatology points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases: cryopyrin-associated periodic syndromes, tumour necrosis factor receptor-associated periodic syndrome, mevalonate kinase deficiency, and deficiency of the interleukin-1 receptor antagonist, 2022, Annals of the Rheumatic Diseases

Frequent co-authors of Goldbach-Mansky include:

  • Adriana A. de Jesus (36 collaborations)
  • Sara Alehashemi (25 collaborations)
  • Scott Canna (11 collaborations)
  • Farzana Bhuyan (10 collaborations)
  • Jeffrey I. Cohen (9 collaborations)

Their work has been published predominantly in journals such as:

  • Annals of the Rheumatic Diseases (7 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • Arthritis & Rheumatology (6 publications)
  • Frontiers in Immunology (5 publications)
  • Stem Cell Research (5 publications)

Main research topics encompass areas such as:

  • Inflammasome and immune disorders (74 publications)
  • Interferon and immune responses (36 publications)
  • Autoimmune and Inflammatory Disorders Research (30 publications)
  • Systemic Lupus Erythematosus Research (20 publications)
  • IL-33, ST2, and ILC Pathways (14 publications)
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms (14 publications)
  • Immunodeficiency and Autoimmune Disorders (12 publications)

Goldbach-Mansky received recognition as a member of the Association of American Physicians, reflecting participation in a professional body related to their field.

Best Publications

  • Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

    Paul Bastard;Paul Bastard;Paul Bastard;Lindsey B. Rosen;Qian Zhang;Eleftherios Michailidis

  • Activated STING in a Vascular and Pulmonary Syndrome

    Y. Liu;A.A. Jesus;B. Marrero;D. Yang

  • The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

    Geun-Shik Lee;Naeha Subramanian;Andrew I. Kim;Ivona Aksentijevich

  • An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

    Ivona Aksentijevich;Seth L. Masters;Polly J. Ferguson;Paul Dancey

  • TNF downmodulates the function of human CD4+CD25hi T-regulatory cells.

    Xavier Valencia;Geoffrey Stephens;Raphaela Goldbach-Mansky;Mildred Wilson

  • Neonatal-Onset Multisystem Inflammatory Disease Responsive to Interleukin-1β Inhibition

    Raphaela Goldbach-Mansky;Natalie J Dailey;Scott W Canna;Ana Gelabert

  • De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases.

    Ivona Aksentijevich;Miroslawa Nowak;Mustapha Mallah;Jae Jin Chae

  • Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

    Qing Zhou;Dan Yang;Amanda K Ombrello;Andrey V Zavialov

  • An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

    Scott W. Canna;Adriana Almeida de Jesus;Sushanth Gouni;Stephen R. Brooks

  • Autoinflammatory Disease Reloaded: A Clinical Perspective

    Daniel L. Kastner;Ivona Aksentijevich;Raphaela Goldbach-Mansky

  • Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset.

    Raphaela Goldbach-Mansky;Jennifer Lee;Angela McCoy;Joseph Hoxworth

  • IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE.

    Shu Wang;Jingya Wang;Varsha Kumar;Jodi L Karnell

  • Classification criteria for autoinflammatory recurrent fevers

    Marco Gattorno;Michael Hofer;Silvia Federici;Federica Vanoni

  • JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies

    Gina A. Montealegre Sanchez;Adam L Reinhardt;Suzanne Ramsey;Helmut Wittkowski

  • Mutations in proteasome subunit β type 8 cause chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature with evidence of genetic and phenotypic heterogeneity.

    Yin Liu;Yuval Ramot;Antonio Torrelo;Amy S. Paller

  • PSORS2 Is Due to Mutations in CARD14

    Catherine T. Jordan;Li Cao;Elisha D.O. Roberson;Katherine C. Pierson

  • The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model.

    Ivona Aksentijevich;Christopher D. Putnam;Elaine F. Remmers;James L. Mueller

  • The Tumor-Necrosis-Factor Receptor–Associated Periodic Syndrome: New Mutations in TNFRSF1A, Ancestral Origins, Genotype-Phenotype Studies, and Evidence for Further Genetic Heterogeneity of Periodic Fevers

    Ivona Aksentijevich;Jérôme Galon;Miguel Soares;Elizabeth Mansfield

  • IL-1 family nomenclature

    Charles Dinarello;William Arend;John Sims;Dirk Smith

  • Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis

    Catherine T. Jordan;Li Cao;Elisha D.O. Roberson;Shenghui Duan

Frequent Co-Authors

Daniel L. Kastner
Daniel L. Kastner National Institutes of Health
Ivona Aksentijevich
Ivona Aksentijevich National Institutes of Health
Massimo Gadina
Massimo Gadina National Institutes of Health
Seza Ozen
Seza Ozen Hacettepe University
Robert Wesley
Robert Wesley National Institutes of Health
Hal M. Hoffman
Hal M. Hoffman University of California, San Diego
Marco Gattorno
Marco Gattorno Istituto Giannina Gaslini
Hani El-Gabalawy
Hani El-Gabalawy University of Manitoba
Helen J. Lachmann
Helen J. Lachmann University College London
Anne M. Bowcock
Anne M. Bowcock Icahn School of Medicine at Mount Sinai

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