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D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
19304
World Ranking
5342
National Ranking
2532

Overview

Mariusz A. Wasik is affiliated with the University of Pennsylvania in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily addresses molecular biology, oncology, cancer research, pathology and forensic medicine, and genetics.

Their work encompasses various main topics, including:

  • Lymphoma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Cancer Genomics and Diagnostics
  • DNA Repair Mechanisms
  • Acute Myeloid Leukemia Research
  • Cancer, Hypoxia, and Metabolism
  • CAR-T cell therapy research

Mariusz A. Wasik has published articles in frequent venues such as:

  • Blood
  • Blood Cancer Journal
  • American Journal of Clinical Pathology
  • Leukemia
  • bioRxiv (Cold Spring Harbor Laboratory)

Among recent publications, the following papers provide insight into their research contributions:

  • Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target, 2020, Haematologica
  • Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication, 2021, Blood Cancer Journal
  • Transdifferentiation of lymphoma into sarcoma associated with profound reprogramming of the epigenome, 2020, Blood
  • Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome, 2020, Blood Cancer Journal
  • TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment, 2020, Cell Reports

The scientist has collaborated regularly with colleagues in their field; frequent co-authors include Reza Nejati, Shengchun Wang, Johnvesly Basappa, Cosimo Lobello, and Jianming Pei, demonstrating ongoing partnerships in advancing cancer and molecular biology research.

Best Publications

  • Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas

    Stephen J. Schuster;Jakub Svoboda;Elise A. Chong;Sunita D. Nasta

  • Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).

    Michal Marzec;Qian Zhang;Ami Goradia;Puthiyaveettil N. Raghunath

  • Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway

    Tomasz Skorski;Alfonso Bellacosa;Margaret Nieborowska‐Skorska;Miroslaw Majewski

  • A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease.

    David S. Kotlyar;Mark T. Osterman;Robert H. Diamond;David Porter

  • Signal Transducer and Activator of Transcription (STAT)5 Activation by BCR/ABL Is Dependent on Intact Src Homology (SH)3 and SH2 Domains of BCR/ABL and Is Required for Leukemogenesis

    Malgorzata Nieborowska-Skorska;Mariusz A. Wasik;Artur Slupianek;Paolo Salomoni

  • Subcutaneous panniculitis-like T-cell lymphoma: clinicopathologic, immunophenotypic, and genotypic analysis of alpha/beta and gamma/delta subtypes.

    Kevin E. Salhany;William R. Macon;John K. Choi;Rosalie Elenitsas

  • Multilevel Dysregulation of STAT3 Activation in Anaplastic Lymphoma Kinase-Positive T/Null-Cell Lymphoma

    Qian Zhang;Puthryaveett N. Raghunath;Liquan Xue;Miroslaw Majewski

  • Role of Phosphatidylinositol 3-Kinase-Akt Pathway in Nucleophosmin/Anaplastic Lymphoma Kinase-mediated Lymphomagenesis

    Artur Slupianek;Margaret Nieborowska-Skorska;Grazyna Hoser;Andrea Morrione

  • Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome.

    Qian Zhang;Irena Nowak;Eric C. Vonderheid;Alain H. Rook

  • The immunosuppressive macrolide RAD inhibits growth of human Epstein–Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders

    Miroslaw Majewski;Magdalena Korecka;Plamen Kossev;Shiyong Li

  • STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes

    Qian Zhang;Hong Y. Wang;Michal Marzec;Puthiyaveettil N. Raghunath

  • Diagnostic microrna profiling in cutaneous t-cell lymphoma (ctcl)

    Ulrik Ralfkiaer;Peter Hagedorn;Charlotte Busch Ahler;Carsten Geisler

  • In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3.

    V H Sommer;O J Clemmensen;O Nielsen;M Wasik

  • Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy

    Vijay G. Bhoj;Dimitrios Arhontoulis;Gerald Wertheim;James Capobianchi

  • STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

    Qian Zhang;Hong Y. Wang;Hong Y. Wang;Anders Woetmann;Anders Woetmann;Puthiyaveettil N. Raghunath;Puthiyaveettil N. Raghunath

  • Constitutive stat3-activation in Sezary syndrome: tyrphostin AG490 inhibits stat3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells

    K W Eriksen;K Kaltoft;G Mikkelsen;M Nielsen

  • Lymphoid Hyperplasia, Autoimmunity, and Compromised Intestinal Intraepithelial Lymphocyte Development in Colitis-Free Gnotobiotic IL-2-Deficient Mice

    Nikhat V. Contractor;Hamid Bassiri;Tannishtha Reya;Audrey Y. Park

  • Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses.

    Miroslaw Majewski;Magdalena Korecka;Joanne Joergensen;Leona Fields

  • Lack of phosphotyrosine phosphatase SHP-1 expression in malignant T-cell lymphoma cells results from methylation of the SHP-1 promoter.

    Qian Zhang;Puthiyaveettil N. Raghunath;Eric Vonderheid;Niels Ødum

  • The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma

    Marco Ruella;Saad S. Kenderian;Olga Shestova;Joseph A. Fraietta

Frequent Co-Authors

Niels Ødum
Niels Ødum University of Copenhagen
Anders Woetmann
Anders Woetmann University of Copenhagen
Carsten Geisler
Carsten Geisler University of Copenhagen
Carl H. June
Carl H. June University of Pennsylvania
Tomasz Skorski
Tomasz Skorski Temple University
Simon F. Lacey
Simon F. Lacey University of Pennsylvania
David L. Porter
David L. Porter University of Pennsylvania
Leslie M. Shaw
Leslie M. Shaw University of Pennsylvania
Bruno Calabretta
Bruno Calabretta Thomas Jefferson University
Lars Iversen
Lars Iversen Aarhus University Hospital

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