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Chemistry

D-Index
44
Citations
6600
World Ranking
16920
National Ranking
198

Overview

Léon Ghosez is affiliated with the Université Catholique de Louvain in Belgium and has contributed extensively to the fields of Chemistry and Materials Science, focusing primarily on Organic Chemistry and Materials Chemistry. Their research spans several specialized subfields, including Inorganic Chemistry, Pharmacology, and Biotechnology.

The main topics that Léon Ghosez has worked on include:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Synthesis and Catalytic Reactions
  • Advanced Synthetic Organic Chemistry
  • Synthesis of β-Lactam Compounds
  • Cyclopropane Reaction Mechanisms
  • Vanadium and Halogenation Chemistry

Ghosez's publications have appeared in multiple peer-reviewed journals. The frequent publication venues include:

  • The Cambridge Structural Database
  • Tetrahedron
  • The Journal of Organic Chemistry
  • Chemistry - A European Journal
  • Synthesis

Selected recent papers illustrate the range of their research interests and include:

  • "Mechanisms and Conformational Control of (4 + 2) and (2 + 2) Cycloadditions of Dienes to Keteniminium Cations," 2020, The Journal of Organic Chemistry
  • "A mild method for the replacement of a hydroxyl group by halogen: 2. unified procedure and stereochemical studies," 2020, Tetrahedron
  • "A mild method for the replacement of a hydroxyl group by halogen: 3. the dichotomous behavior of α-haloenamines towards allylic and propargylic alcohols," 2021, Tetrahedron
  • "Computational Exploration of Anomalous Regioselectivities in Cycloadditions of Ketenes to Oxazolines," 2022, The Journal of Organic Chemistry
  • "Productive Syntheses of Privileged Scaffolds Inspired by the Recognition of a Diels-Alder Pattern Common to Three Classes of Natural Products," 2020, Chemistry - A European Journal

Léon Ghosez has collaborated frequently with several co-authors, including:

  • K. Harsha Vardhan Reddy
  • Eduard Badarau
  • Aurore Loudet
  • Charles Simon
  • Laurent Trembleau

Best Publications

  • SYNTHESIS OF ACYL HALIDES UNDER VERY MILD CONDITIONS

    A. Devos;J. Remion;A.-M. Frisque-Hesbain;A. Colens

  • Cyclobutanone and Cyclobutenone Derivatives By Reaction of Tertiary Amides With Alkenes Or Alkynes

    Jean-Bernard Falmagne;José Escudero;Sofia Taleb-Sahraoui;Léon Ghosez

  • Trimethylsilyl bis(trifluoromethanesulfonyl)imide as a tolerant and environmentally benign Lewis acid catalyst of the Diels–Alder reaction

    Bernard Mathieu;Léon Ghosez;Léon Ghosez

  • Inhibition of metallo-beta-lactamases by a series of mercaptoacetic acid thiol ester derivatives.

    DJ Payne;JH Bateson;BC Gasson;D Proctor

  • Cycloadditions of dichloroketene to olefins and dienes

    L. Ghosez;R. Montaigne;A. Roussel;H. Vanlierde

  • 1-AZA-1,3-dienes. Diels-alder reactions with α, β-unsaturated hydrazones.

    Béatrice Serckx-Poncin;Anne-Marie Hesbain-Frisque;Léon Ghosez

  • N-Trimethylsilyl-bis(trifluoromethanesulfonyl)imide: a better carbonyl activator than trimethylsilyl triflate

    Benoit Mathieu;Léon Ghosez

  • A Diels-alder Route To Pyridone and Piperidone Derivatives

    Francy Sainte;Béatrice Serckx-Poncin;Anne-Marie Frisque-Hesbain;Léon Ghosez

  • Asymmetric Diels-Alder reactions of 2-azadienes catalyzed by a chiral copper(II) complex. A general route to enantiomerically pure piperidones

    Eric Jnoff;Léon Ghosez

  • Intramolecular [2+2] cycloadditions of ketenes and keteniminium salts to olefins

    Istvan Marko;Bruno Ronsmans;Anne Marie Hesbain-Frisque;Stephane Dumas

  • Cycloadditions of keteneimmonium cations to olefins and dienes. New synthesis of four-membered rings

    Jacqueline Marchand-Brynaert;Léon Ghosez

  • Models for Asymmetric [2+2] Cyclo-additions

    Catherine Houge;Anne-Marie Frisque-Hesbain;Anne Mockel;Léon Ghosez

  • Study of Chiral Auxiliaries for the Intramolecular [2+2] Cycloaddition of a Keteniminium Salt To An Olefinic Double-bond - a New Asymmetric-synthesis of Cyclobutanones

    Lian-yong Chen;Léon Ghosez

  • 1-Amino-2-azadienes from the thermolysis of 2-amino-1-azirines. New reagents for the construction of pyridine and dihydropyridine rings

    Andre Demoulin;Hugo Gorissen;Anne-Marie Hesbain-Frisque;Leon Ghosez

  • Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases?

    Jean Dessolin;Marie Schuler;Alice Quinart;Francesca De Giorgi

  • Alkyl and Aryl α-Chloro Enamines

    L. Ghosez;B. Haveaux;H. G. Viehe

  • Synthesis of Alkyl-halides Under Neutral Conditions

    François Munyemana;Anne-Marie Frisque-Hesbain;Alain Devos;Léon Ghosez

  • Synthesis and reactions of 2-amino-1-azirines

    Maurice Rens;Léon Ghosez

  • 2-aza-1,3-dienes: Methods of synthesis and stereochemical studies

    L. Ghosez;Ph. Bayard;P. Nshimyumukiza;V. Gouverneur

  • A practical route towards α,β-unsaturated δ-lactones based on a [3+3] strategy. Synthesis of (−)-argentilactone

    Juan Carlos Carretero;Léon Ghosez

Frequent Co-Authors

Jacqueline Marchand-Brynaert
Jacqueline Marchand-Brynaert Université Catholique de Louvain
Juan C. Carretero
Juan C. Carretero Autonomous University of Madrid
Bernard Tinant
Bernard Tinant Université Catholique de Louvain
István E. Markó
István E. Markó Université Catholique de Louvain
Kendall N. Houk
Kendall N. Houk University of California, Los Angeles
Reiner Sustmann
Reiner Sustmann University of Duisburg-Essen
Brice Kauffmann
Brice Kauffmann University of Bordeaux
Jean-Michel Léger
Jean-Michel Léger University of Poitiers
David J. Payne
David J. Payne GlaxoSmithKline (United Kingdom)
Paul M. Tulkens
Paul M. Tulkens Université Catholique de Louvain

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