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Hisashi Yamamoto

Hisashi Yamamoto

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Chemistry
Japan
2026

D-Index & Metrics

Chemistry

D-Index
114
Citations
42982
World Ranking
680
National Ranking
29

Research.com Recognitions

  • 2026 - Research.com Chemistry in Japan Leader Award
  • 2025 - Research.com Chemistry in Japan Leader Award
  • 2022 - Research.com Chemistry in Japan Leader Award
  • 2011 - Ryoji Noyori Prize, Society of Synthetic Organic Chemistry
  • 2011 - Fellow of the American Academy of Arts and Sciences
  • 2006 - Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry, Elsevier
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Hisashi Yamamoto is affiliated with Chubu University in Japan and has made significant contributions to the fields of Chemistry and Biochemistry, Genetics and Molecular Biology. Their research largely focuses on Organic Chemistry and Molecular Biology, with additional work in Biomedical Engineering, Pharmaceutical Science, and Oncology.

Their expertise encompasses a range of topics, including Chemical Synthesis and Analysis, Click Chemistry and Applications, Synthetic Organic Chemistry Methods, Sulfur-Based Synthesis Techniques, Fluorine in Organic Chemistry, Synthesis and Catalytic Reactions, and Radical Photochemical Reactions.

Yamamoto has published extensively across various reputable venues. Frequent publication outlets include:

  • Synfacts
  • Journal of the American Chemical Society
  • Chemical Science
  • Organic Letters
  • Chemical and Pharmaceutical Bulletin

Collaborations have played a notable role in Yamamoto's research output. Frequent coauthors include:

  • Tomohiro Hattori
  • Wataru Muramatsu
  • An Wu
  • Isai Ramakrishna

Some of the recent papers authored or coauthored by Yamamoto illustrate ongoing research interests and developments:

  • Peptide Bond-Forming Reaction via Amino Acid Silyl Esters: New Catalytic Reactivity of an Aminosilane (2020, ACS Catalysis)
  • Game Change from Reagent- to Substrate-Controlled Peptide Synthesis (2020, Bulletin of the Chemical Society of Japan)
  • Amide bond formation: beyond the dilemma between activation and racemisation (2021, Chemical Communications)
  • Protective effect of d-alanine against acute kidney injury (2022, American Journal of Physiology-Renal Physiology)
  • Peptide Bond Formation of Amino Acids by Transient Masking with Silylating Reagents (2021, Journal of the American Chemical Society)

Yamamoto has been recognized with various awards, including:

  • Ryoji Noyori Prize, Society of Synthetic Organic Chemistry (2011)
  • Fellow of the American Academy of Arts and Sciences (2011)
  • Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry, Elsevier (2006)
  • Fellow of the American Association for the Advancement of Science (AAAS) (2003)

Best Publications

  • Comprehensive Asymmetric Catalysis I–III

    Eric N. Jacobsen;Andreas Pfaltz;Hisashi Yamamoto

  • Biologically Active Organofluorine Compounds

    Tamejiro Hiyama;Hisashi Yamamoto

  • "Designer acids": combined acid catalysis for asymmetric synthesis.

    Hisashi Yamamoto;Kentaro Futatsugi

  • Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst

    Hiromi Torii;Masakazu Nakadai;Kazuaki Ishihara;Susumu Saito

  • Lewis acids in organic synthesis

    Hisashi Yamamoto

  • Design of chiral N-triflyl phosphoramide as a strong chiral Brønsted acid and its application to asymmetric Diels-Alder reaction.

    Daisuke Nakashima;Hisashi Yamamoto

  • 3,4,5-Trifluorobenzeneboronic Acid as an Extremely Active Amidation Catalyst.

    Kazuaki Ishihara;Suguru Ohara;Hisashi Yamamoto

  • Scandium Trifluoromethanesulfonate as an Extremely Active Lewis Acid Catalyst in Acylation of Alcohols with Acid Anhydrides and Mixed Anhydrides.

    Kazuaki Ishihara;Manabu Kubota;Hideki Kurihara;Hisashi Yamamoto

  • Design of acid-base catalysis for the asymmetric direct Aldol reaction.

    Susumu Saito;Hisashi Yamamoto

  • Asymmetric silver-catalyzed reactions.

    Marina Naodovic;Hisashi Yamamoto

  • Direct Condensation of Carboxylic Acids with Alcohols Catalyzed by Hafnium(IV) Salts

    Kazuaki Ishihara;Suguru Ohara;Hisashi Yamamoto

  • Asymmetric hetero-Diels-Alder reaction catalyzed by a chiral organoaluminum reagent

    Keiji. Maruoka;Takayuki. Itoh;Tadashi. Shirasaka;Hisashi. Yamamoto

  • Enantioselective tandem O-nitroso Aldol/Michael reaction.

    Yuhei Yamamoto;Norie Momiyama;Hisashi Yamamoto

  • Rich chemistry of nitroso compounds

    Hisashi Yamamoto;Norie Momiyama

  • Brønsted acid catalysis of achiral enamine for regio- and enantioselective nitroso aldol synthesis

    Norie Momiyama;Hisashi Yamamoto

  • SCANDIUM TRIFLUOROMETHANESULFONATE AS AN EXTREMELY ACTIVE ACYLATION CATALYST

    Kazuaki Ishihara;Manabu Kubota;Hideki Kurihara;Hisashi Yamamoto

  • Axially chiral biaryl diols catalyze highly enantioselective hetero-Diels-Alder reactions through hydrogen bonding.

    Aditya K. Unni;Norito Takenaka;Hisashi Yamamoto;Viresh H. Rawal

  • A New Chiral BLA Promoter for Asymmetric Aza Diels-Alder and Aldol-Type Reactions of Imines

    Kazuaki Ishihara;Mayumi Miyata;Kouji Hattori;Toshiji Tada

  • ARYLBORON COMPOUNDS AS ACID CATALYSTS IN ORGANIC SYNTHETIC TRANSFORMATIONS

    Kazuaki Ishihara;Hisashi Yamamoto

  • Organoaluminum-promoted Beckmann rearrangement of oxime sulfonates

    Keiji Maruoka;Tohru Miyazaki;Mamoru Ando;Yasushi Matsumura

  • Cyanuric chloride as a mild and active Beckmann rearrangement catalyst.

    Yoshiro Furuya;Kazuaki Ishihara;Hisashi Yamamoto

  • Rhenium(VII) Oxo Complexes as Extremely Active Catalysts in the Dehydration of Primary Amides and Aldoximes to Nitriles

    Kazuaki Ishihara;Yoshiro Furuya;Hisashi Yamamoto

  • Kombinierte Säurekatalyse in der asymmetrischen Synthese durch “Designer‐Säuren”

    Hisashi Yamamoto;Kentaro Futatsugi

  • Direct ester condensation from a 1:1 mixture of carboxylic acids and alcohols catalyzed by hafnium(IV) or zirconium(IV) salts

    Kazuaki Ishihara;Masaya Nakayama;Suguru Ohara;Hisashi Yamamoto

Frequent Co-Authors

Kazuaki Ishihara
Kazuaki Ishihara Nagoya University
Keiji Maruoka
Keiji Maruoka Kyoto University
Susumu Saito
Susumu Saito Nagoya University
Hitosi Nozaki
Hitosi Nozaki Okayama University
Koichiro Oshima
Koichiro Oshima Kyoto University
E. J. Corey
E. J. Corey Harvard University
Tamejiro Hiyama
Tamejiro Hiyama Chuo University
Takashi Ooi
Takashi Ooi Nagoya University
Atsunori Mori
Atsunori Mori Kobe University
Yong-Gui Zhou
Yong-Gui Zhou Dalian Institute of Chemical Physics

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