Marian F. Young

Overview

Best Publications

• Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche

  Yanming Bi;Driss Ehirchiou;Tina M. Kilts;Colette A. Inkson

  1554
  Citations

• Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species.

  Larry W. Fisher;John D. Termine;Marian F. Young

  1003
  Citations

• The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

  Liliana Schaefer;Andrea Babelova;Eva Kiss;Heinz J. Hausser

  964
  Citations

• Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues.

  Paolo Bianco;Larry W. Fisher;Marian F. Young;John D. Termine

  804
  Citations

• Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontin.

  L.W. Fisher;D.A. Torchia;B. Fohr;M.F. Young

  770
  Citations

• Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice

  Tianshun Xu;Paolo Bianco;Paolo Bianco;Larry W. Fisher;Glenn Longenecker

  673
  Citations

• Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins.

  Larry W Fisher;John T Stubbs;Marian F Young

  651
  Citations

• Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases

  Laurent Ameye;Marian F. Young

  616
  Citations

• Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues.

  A. Corsi;T. Xu;Xiao-dong Chen;A. Boyde

  591
  Citations

• cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN).

  Marian F. Young;Janet M. Kerr;John D. Termine;Ulla M. Wewer

  514
  Citations

• Biglycan: A danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors

  Andrea Babelova;Kristin Moreth;Kristin Moreth;Wasiliki Tsalastra-Greul;Jinyang Zeng-Brouwers;Jinyang Zeng-Brouwers

  509
  Citations

• Expression of bone sialoprotein (BSP) in developing human tissues.

  Paolo Bianco;Larry W. Fisher;Marian F. Young;John D. Termine

  492
  Citations

• Abnormal collagen fibrils in tendons of biglycan/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis

  Laurent Ameye;Dean Aria;Karl Jepsen;Ake Oldberg

  400
  Citations

• The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation

  Xiao Dong Chen;Larry W. Fisher;Pamela Gehron Robey;Marian F. Young

  395
  Citations

• PHOG, a Candidate Gene for Involvement in the Short Stature of Turner Syndrome

  Jay W. Ellison;Zabihullah Wardak;Marian F. Young;Pamela Gehron Robey

  368
  Citations

• Structure, expression, and regulation of the major noncollagenous matrix proteins of bone.

  Marian F. Young;Janet M. Kerr;Kyomi Ibaraki;Anne-Marie Heegaard

  337
  Citations

• A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells

  Masako Miura;Xiao Dong Chen;Matthew R. Allen;Yanming Bi

  332
  Citations

• Extracellular Matrix Proteoglycans Control the Fate of Bone Marrow Stromal Cells

  Yanming Bi;Christina H. Stuelten;Tina Kilts;Sunil Wadhwa

  307
  Citations

• Factor H Binding to Bone Sialoprotein and Osteopontin Enables Tumor Cell Evasion of Complement-mediated Attack

  Neal S. Fedarko;Bert Fohr;Pamela G. Robey;Marian F. Young

  307
  Citations

• Osteonectin cDNA sequence reveals potential binding regions for calcium and hydroxyapatite and shows homologies with both a basement membrane protein (SPARC) and a serine proteinase inhibitor (ovomucoid).

  Mark E. Bolander;Marian F. Young;Larry W. Fisher;Yoshihiko Yamada

  267
  Citations