D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 46 Citations 7,737 79 World Ranking 12540 National Ranking 5366

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Peter J. Neame mostly deals with Biochemistry, Aggrecan, Molecular biology, Proteoglycan and Peptide sequence. His Biochemistry research is mostly focused on the topic Cleavage. Peter J. Neame interconnects ADAMTS4 Protein, Synovial fluid and Aggrecanase in the investigation of issues within Aggrecan.

The study of Extracellular matrix and Cartilage are components of his Proteoglycan research. His Cartilage research is multidisciplinary, relying on both Matrix metalloproteinase, Metalloproteinase and Cell biology. The study incorporates disciplines such as Amino acid, Leucine-rich repeat and Biglycan in addition to Peptide sequence.

His most cited work include:

  • The structure of aggrecan fragments in human synovial fluid : Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis (402 citations)
  • The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain. (370 citations)
  • Degradation of cartilage aggrecan by collagenase-3 (MMP-13) (327 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Biochemistry, Proteoglycan, Peptide sequence, Molecular biology and Cartilage. He applies his multidisciplinary studies on Biochemistry and Aggrecan in his research. His Aggrecan research integrates issues from ADAMTS4 Protein, Synovial fluid and Aggrecanase.

The concepts of his Proteoglycan study are interwoven with issues in Iduronic acid, Glycoprotein, Glycosaminoglycan and Peptide. His research investigates the connection between Peptide sequence and topics such as Cysteine that intersect with problems in C-terminus. In Molecular biology, Peter J. Neame works on issues like Complementary DNA, which are connected to Furin.

He most often published in these fields:

  • Biochemistry (72.34%)
  • Proteoglycan (47.87%)
  • Peptide sequence (38.30%)

What were the highlights of his more recent work (between 1999-2010)?

  • Molecular biology (37.23%)
  • Biochemistry (72.34%)
  • Cell biology (18.09%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Molecular biology, Biochemistry, Cell biology, Peptide sequence and Complementary DNA. The Molecular biology study combines topics in areas such as Fibroblast growth factor receptor 4, Fibroblast growth factor receptor, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 2 and Gene isoform. His work in the fields of Biochemistry, such as Proteoglycan and Small Leucine-Rich Proteoglycans, overlaps with other areas such as Aggrecan.

His Cell biology study integrates concerns from other disciplines, such as Receptor, Chromosome, Cartilage and Transfection. His study on Amino acid sequence analysis is often connected to Text mining, Terminal and Asporin as part of broader study in Peptide sequence. His work deals with themes such as Conserved sequence and Radiation hybrid mapping, Gene mapping, which intersect with Complementary DNA.

Between 1999 and 2010, his most popular works were:

  • Identification and characterization of asporin. a novel member of the leucine-rich repeat protein family closely related to decorin and biglycan. (179 citations)
  • Independent modulation of collagen fibrillogenesis by decorin and lumican (124 citations)
  • Low frequency EMF regulates chondrocyte differentiation and expression of matrix proteins (116 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

His main research concerns Biochemistry, Proteoglycan, Aggrecan, Extracellular matrix and Molecular biology. His study in the fields of Chondroitin sulfate under the domain of Biochemistry overlaps with other disciplines such as Asporin. He combines subjects such as Biophysics and Fibril formation with his study of Proteoglycan.

His Extracellular matrix research includes themes of Chondrocyte, Cartilage, Endochondral ossification and Type II collagen. His Molecular biology research includes elements of Biglycan, Decorin, Leucine-rich repeat, Protein family and Peptide sequence. His Decorin research incorporates elements of Fibril, Fibrillogenesis and Consensus sequence.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The structure of aggrecan fragments in human synovial fluid : Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

L. Stefan Lohmander;Peter J. Neame;John D. Sandy.
Arthritis & Rheumatism (1993)

622 Citations

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain.

J D Sandy;C R Flannery;P J Neame;L S Lohmander.
Journal of Clinical Investigation (1992)

566 Citations

Degradation of cartilage aggrecan by collagenase-3 (MMP-13)

Amanda J. Fosang;Vera Knäuper;Gillian Murphy.
FEBS Letters (1996)

504 Citations

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain.

J D Sandy;P J Neame;R E Boynton;C R Flannery.
Journal of Biological Chemistry (1991)

392 Citations

The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B.

Amanda J Fosang;Peter J Neame;Tim E Hardingham.
Journal of Biological Chemistry (1992)

339 Citations

Identification and characterization of asporin. a novel member of the leucine-rich repeat protein family closely related to decorin and biglycan.

Pilar Lorenzo;Anders Aspberg;Patrik Önnerfjord;Michael T. Bayliss.
Journal of Biological Chemistry (2001)

223 Citations

The primary structure of the core protein of the small, leucine-rich proteoglycan (PG I) from bovine articular cartilage

P J Neame;H U Choi;L C Rosenberg.
Journal of Biological Chemistry (1989)

215 Citations

The link proteins

P J Neame;F P Barry.
Cellular and Molecular Life Sciences (1993)

198 Citations

The Structure of Aggrecan Fragments in Human Synovial Fluid

John D. Sandy;R. Flannery;Peter J. Neame;L. Stefan Lohmanderl.
(1992)

187 Citations

Independent modulation of collagen fibrillogenesis by decorin and lumican

P. J. Neame;C. J. Kay;D. J. McQuillan;M. P. Beales.
Cellular and Molecular Life Sciences (2000)

187 Citations

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