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Immunology

D-Index
51
Citations
11873
World Ranking
4128
National Ranking
1883

Overview

Kenneth E. Ugen is affiliated with the University of South Florida in the United States. Their research primarily focuses on Medicine, with particular expertise in subfields such as Infectious Diseases, Hepatology, Public Health, Environmental and Occupational Health, Parasitology, and Epidemiology.

Their work encompasses several main topics, including:

  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • Vector-borne infectious diseases
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Hepatitis Viruses Studies and Epidemiology
  • SARS-CoV-2 and COVID-19 Research

Kenneth E. Ugen has contributed to research published across a range of scientific venues, including:

  • PLoS neglected tropical diseases
  • Human Vaccines & Immunotherapeutics
  • ACS Pharmacology & Translational Science

Their recent publications include:

  • "A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus," 2020, PLoS neglected tropical diseases
  • "Neutralization of hepatitis B virus by a novel DNA-encoded monoclonal antibody," 2020, Human Vaccines & Immunotherapeutics
  • "Identification of Novel Neutralizing Monoclonal Antibodies against SARS-CoV-2 Spike Glycoprotein," 2021, ACS Pharmacology & Translational Science

Frequent collaborators in their research include Michelle Ho, David B. Weiner, Kar Muthumani, Hyeree Choi, and Sagar B. Kudchodkar. These collaborations indicate ongoing work in immunology and infectious disease research consistent with Ugen's fields of study.

Best Publications

  • A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

    Dave Morgan;David M. Diamond;Paul E. Gottschall;Kenneth E. Ugen

  • Gene inoculation generates immune responses against human immunodeficiency virus type 1.

    Bin Wang;Kenneth E. Ugen;Vasantha Srikantan;Michael G. Agadjanyan

  • Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma.

    Adil I. Daud;Ronald C. DeConti;Stephanie Andrews;Patricia Urbas

  • First Human Trial of a DNA-Based Vaccine for Treatment of Human Immunodeficiency Virus Type 1 Infection: Safety and Host Response

    Rob Roy MacGregor;Jean D. Boyer;Kenneth E. Ugen;Kim E. Lacy

  • Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination.

    Jean D. Boyer;Kenneth E. Ugen;Bin Wang;Michael Agadjanyan

  • Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

    Donna M. Wilcock;Giovanni DiCarlo;Debbi Henderson;Jennifer Jackson

  • Microglial activation facilitates Aβ plaque removal following intracranial anti-Aβ antibody administration

    Donna M Wilcock;Sanjay K Munireddy;Arnon Rosenthal;Kenneth E Ugen

  • A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates

    Karuppiah Muthumani;Darryl Falzarano;Emma L. Reuschel;Colleen Tingey

  • DNA inoculation induces neutralizing immune responses against human immunodeficiency virus type 1 in mice and nonhuman primates.

    Ban Wang;Jean Boyer;Vasantha Srikantan;Leslie Coney

  • Enhancement of protective humoral (Th2) and cell-mediated (Th1) immune responses against herpes simplex virus-2 through co-delivery of granulocyte-macrophage colony-stimulating factor expression cassettes.

    Jeong-Im Sin;Jong J. Kim;Kenneth E. Ugen;Richard B. Ciccarelli

  • In vivo protective anti-HIV immune responses in non-human primates through DNA immunization.

    Jean D. Boyer;Bin Wang;Kenneth E. Ugen;Michael Agadjanyan

  • Number of Aβ Inoculations in APP+PS1 Transgenic Mice Influences Antibody Titers, Microglial Activation, and Congophilic Plaque Levels

    Donna M. Wilcock;Marcia N. Gordon;Kenneth E. Ugen;Paul E. Gottschall

  • Induction of Humoral and Cellular Immune Responses to the Human Immunodeficiency Type 1 Virus in Nonhuman Primates by in Vivo DNA Inoculation

    Bin Wang;Jean Boyer;Vasantha Srikantan;Kenneth Ugen

  • In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine

    Karuppiah Muthumani;Bryan D Griffin;Bryan D Griffin;Sangya Agarwal;Sagar B Kudchodkar

  • DNA vaccination with HIV-1 expressing constructs elicits immune responses in humans

    Kenneth E. Ugen;Susan B. Nyland;Jean D. Boyer;Cristina Vidal

  • Immunization by Direct DNA Inoculation Induces Rejection of Tumor Cell Challenge

    Bin Wang;Michael Merva;Kesen Dang;Kenneth E. Ugen

  • T-cell responses induced in normal volunteers immunized with a DNA-based vaccine containing HIV-1 env and rev.

    Rob Roy MacGregor;Richard Ginsberg;Kenneth E Ugen;Yaela Baine

  • DNA Vaccines against Human Immunodeficiency Virus Type 1 in the Past Decade

    Malavika Giri;Kenneth E. Ugen;David B. Weiner

  • The galactosyl ceramide/sulfatide receptor binding region of HIV-1 gp120 maps to amino acids 206-275

    Shama Bhat;Richard V. Mettus;E. Premkumar Reddy;K.E. Ugen

  • Antigen-specific humoral and cellular immune responses can be modulated in rhesus macaques through the use of IFN-γ, IL-12, or IL-18 gene adjuvants

    Jong J. Kim;Liesl K. Nottingham;Anthony Tsai;Daniel J. Lee

Frequent Co-Authors

David B. Weiner
David B. Weiner The Wistar Institute
Jean D. Boyer
Jean D. Boyer Inovio Pharmaceuticals (United States)
William V. Williams
William V. Williams GlaxoSmithKline (United Kingdom)
Karuppiah Muthumani
Karuppiah Muthumani The Wistar Institute
Marcia N. Gordon
Marcia N. Gordon Michigan State University
Niranjan Y. Sardesai
Niranjan Y. Sardesai University of Pennsylvania
Richard Heller
Richard Heller University of South Florida
Chad A. Dickey
Chad A. Dickey University of South Florida
Rob Roy MacGregor
Rob Roy MacGregor University of Pennsylvania
Gary Kobinger
Gary Kobinger The University of Texas Medical Branch at Galveston

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