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Biology and Biochemistry

D-Index
59
Citations
9712
World Ranking
12809
National Ranking
885

Overview

Akira Tokumura is affiliated with Yasuda Women's University in Japan and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses a significant focus on molecular biology with additional specialization in biochemistry, pharmacology, physiology, and spectroscopy.

Their primary topics of investigation include:

  • Sphingolipid Metabolism and Signaling
  • Lipid Membrane Structure and Behavior
  • Cannabis and Cannabinoid Research
  • Erythrocyte Function and Pathophysiology
  • Lipid Metabolism and Biosynthesis
  • Metabolomics and Mass Spectrometry Studies
  • Pancreatic Function and Diabetes

Akira Tokumura has published numerous papers, with several appearing in notable journals such as Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Prostaglandins & Other Lipid Mediators, Chromatography, Archives of Virology, and Biochemical and Biophysical Research Communications.

Representative recent publications include:

  • "Identification of human glycerophosphodiesterase 3 as an ecto phospholipase C that converts the G protein-coupled receptor 55 agonist lysophosphatidylinositol to bioactive monoacylglycerols in cultured mammalian cells," 2020, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • "Involvement of acid ceramidase in the degradation of bioactive N-acylethanolamines," 2021, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • "Phospholipid analysis of two influenza A virus-infected cell lines differing in their viral replication kinetics," 2023, Archives of Virology
  • "A low level of lysophosphatidic acid in human gingival crevicular fluid from patients with periodontitis due to high soluble lysophospholipase activity: Its potential protective role on alveolar bone loss by periodontitis," 2020, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  • "Extracellular and intracellular productions of lysophosphatidic acids and cyclic phosphatidic acids by lysophospholipase D from exogenously added lysophosphatidylcholines to cultured NRK52E cells," 2023, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Frequent co-authors of Akira Tokumura include:

  • Toshihiko Tsutsumi
  • Kohei Kawabata
  • Tamotsu Tanaka
  • Hiroyuki Nishi
  • Risa Matsuda

The volume of publications in specific venues indicates a particular connection with Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, where they have contributed five papers. Other journals with multiple contributions include Prostaglandins & Other Lipid Mediators and Chromatography.

Best Publications

  • Identification of Human Plasma Lysophospholipase D, a Lysophosphatidic Acid-producing Enzyme, as Autotaxin, a Multifunctional Phosphodiesterase

    Akira Tokumura;Eiji Majima;Yuko Kariya;Kyoko Tominaga

  • Lysophosphatidic acids induce proliferation of cultured vascular smooth muscle cells from rat aorta

    A Tokumura;M Iimori;Y Nishioka;M Kitahara

  • A family of phospholipid autacoids: Occurrence, metabolism and bioactions

    Akira Tokumura

  • Effects of synthetic and natural lysophosphatidic acids on the arterial blood pressure of different animal species

    Akira Tokumura;Kenji Fukuzawa;Hiroaki Tsukatani

  • 2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through Ca2+-dependent and -independent mechanisms

    Sachiko Kondo;Hironori Kondo;Shinji Nakane;Tomoko Kodaka

  • Antioxidative effect of alpha-tocopherol incorporation into lecithin liposomes on ascorbic acid-Fe2+-induced lipid peroxidation.

    Kenji Fukuzawa;Hisako Chida;Akira Tokumura;Hiroaki Tsukatani

  • Production of Lysophosphatidic Acids by Lysophospholipase D in Human Follicular Fluids of In Vitro Fertilization Patients

    Akira Tokumura;Maki Miyake;Yuko Nishioka;Shuji Yamano

  • Lysophosphatidic acid, a growth factor-like lipid, in the saliva

    Takayuki Sugiura;Shinji Nakane;Seishi Kishimoto;Keizo Waku

  • Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis

    Akira Tokumura;Laura D. Carbone;Laura D. Carbone;Yasuko Yoshioka;Junichi Morishige

  • Antioxidant activities of tocopherols on Fe2+-ascorbate-induced lipid peroxidation in lecithin liposomes

    Kenji Fukuzawa;Akira Tokumura;Setsuhiro Ouchi;Hiroaki Tsukatani

  • Rate constants for quenching singlet oxygen and activities for inhibiting lipid peroxidation of carotenoids and α-tocopherol in liposomes

    Kenji Fukuzawa;Yasuki Inokami;Akira Tokumura;Junji Terao

  • Evidence for existence of various homologues and analogues of platelet activating factor in a lipid extract of bovine brain

    Akira Tokumura;Koumei Kamiyasu;Kenkichi Takauchi;Hiroaki Tsukatani

  • Increased production of bioactive lysophosphatidic acid by serum lysophospholipase D in human pregnancy

    Akira Tokumura;Yumi Kanaya;Maki Miyake;Shuji Yamano

  • Occurrence of lysophosphatidic acid and its alkyl ether-linked analog in rat brain and comparison of their biological activities toward cultured neural cells.

    Takayuki Sugiura;Shinji Nakane;Seishi Kishimoto;Keizo Waku

  • Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways.

    Kazuhito Tsuboi;Yasuo Okamoto;Yasuo Okamoto;Natsuki Ikematsu;Manami Inoue

  • 2-Arachidonoyl-sn-glycero-3-phosphate, an arachidonic acid-containing lysophosphatidic acid: occurrence and rapid enzymatic conversion to 2-arachidonoyl-sn-glycerol, a cannabinoid receptor ligand, in rat brain.

    Shinji Nakane;Saori Oka;Shunsuke Arai;Keizo Waku

  • Physiological and pathophysiological roles of lysophosphatidic acids produced by secretory lysophospholipase D in body fluids.

    Akira Tokumura

  • Accumulation of VariousN-Acylethanolamines IncludingN-Arachidonoylethanolamine (Anandamide) in Cadmium Chloride-Administered Rat Testis

    Sachiko Kondo;Takayuki Sugiura;Tomoko Kodaka;Naomi Kudo

  • Biochemical Characterization of the Interaction of Lipid Phosphoric Acids with Human Platelets: Comparison with Platelet Activating Factor

    T. Sugiura;A. Tokumura;L. Gregory;T. Nouchi

  • Ether-linked analogue of 2-arachidonoylglycerol (noladin ether) was not detected in the brains of various mammalian species

    Saori Oka;Akiko Tsuchie;Akira Tokumura;Mayumi Muramatsu

Frequent Co-Authors

Kenji Fukuzawa
Kenji Fukuzawa University of Tokushima
Kentaro Kogure
Kentaro Kogure University of Tokushima
Natsuo Ueda
Natsuo Ueda Kagawa University
Keizo Waku
Keizo Waku Teikyo University
Takayuki Sugiura
Takayuki Sugiura Teikyo University
Junji Terao
Junji Terao University of Tokushima
Koichiro Tsuchiya
Koichiro Tsuchiya University of Tokushima
Janusz M. Gebicki
Janusz M. Gebicki Macquarie University
Donald J. Hanahan
Donald J. Hanahan The University of Texas Health Science Center at San Antonio
Arnold E. Postlethwaite
Arnold E. Postlethwaite University of Tennessee Health Science Center

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