Takayuki Sugiura

Overview

Best Publications

• 2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain

  T. Sugiura;S. Kondo;A. Sukagawa;S. Nakane

  3161
  Citations

• Leptin-regulated endocannabinoids are involved in maintaining food intake

  Vincenzo Di Marzo;Sravan K. Goparaju;Lei Wang;Lei Wang;Jie Liu;Jie Liu

  1963
  Citations

• Identification of GPR55 as a lysophosphatidylinositol receptor.

  Saori Oka;Keisuke Nakajima;Atsushi Yamashita;Seishi Kishimoto

  583
  Citations

• Evidence That 2-Arachidonoylglycerol but Not N-Palmitoylethanolamine or Anandamide Is the Physiological Ligand for the Cannabinoid CB2 Receptor COMPARISON OF THE AGONISTIC ACTIVITIES OF VARIOUS CANNABINOID RECEPTOR LIGANDS IN HL-60 CELLS

  Takayuki Sugiura;Sachiko Kondo;Seishi Kishimoto;Tomoyuki Miyashita

  555
  Citations

• Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance.

  T. Sugiura;Y. Kobayashi;S. Oka;K. Waku

  489
  Citations

• Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand.

  Takayuki Sugiura;Seishi Kishimoto;Saori Oka;Maiko Gokoh

  464
  Citations

• Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor STRUCTURE-ACTIVITY RELATIONSHIP OF 2-ARACHIDONOYLGLYCEROL, ETHER-LINKED ANALOGUES, AND RELATED COMPOUNDS

  Takayuki Sugiura;Tomoko Kodaka;Shinji Nakane;Tomoyuki Miyashita

  457
  Citations

• Acyltransferases and Transacylases Involved in Fatty Acid Remodeling of Phospholipids and Metabolism of Bioactive Lipids in Mammalian Cells

  Atsushi Yamashita;Takayuki Sugiura;Keizo Waku

  428
  Citations

• 2-Arachidonoylglycerol and the cannabinoid receptors.

  Takayuki Sugiura;Keizo Waku

  321
  Citations

• Acyltransferases and transacylases that determine the fatty acid composition of glycerolipids and the metabolism of bioactive lipid mediators in mammalian cells and model organisms.

  Atsushi Yamashita;Yasuhiro Hayashi;Yoko Nemoto-Sasaki;Makoto Ito

  298
  Citations

• Synaptically Driven Endocannabinoid Release Requires Ca2+-Assisted Metabotropic Glutamate Receptor Subtype 1 to Phospholipase C β4 Signaling Cascade in the Cerebellum

  Takashi Maejima;Saori Oka;Yuki Hashimotodani;Takako Ohno-Shosaku

  296
  Citations

• Transacylase‐Mediated and Phosphodiesterase‐Mediated Synthesis of N‐Arachidonoylethanolamine, an Endogenous Cannabinoid‐Receptor Ligand, in Rat Brain Microsomes

  Takayuki Sugiura;Sachiko Kondo;Akihiro Sukagawa;Takashi Tonegawa

  296
  Citations

• The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide.

  V Di Marzo;T Bisogno;T Sugiura;D Melck

  292
  Citations

• Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities.

  Takayuki Sugiura;Sachiko Kondo;Akihiro Sukagawa;Takashi Tonegawa

  284
  Citations

• 2-Arachidonoylglycerol, a Putative Endogenous Cannabinoid Receptor Ligand, Induces Rapid, Transient Elevation of Intracellular Free Ca2+in Neuroblastoma × Glioma Hybrid NG108-15 Cells

  Takayuki Sugiura;Tomoko Kodaka;Sachiko Kondo;Takashi Tonegawa

  245
  Citations

• 2-Arachidonoyl-sn-glycero-3-phosphoinositol: A Possible Natural Ligand for GPR55

  Saori Oka;Toshinobu Toshida;Kanako Maruyama;Keisuke Nakajima

  244
  Citations

• 2-Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through Ca2+-dependent and -independent mechanisms

  Sachiko Kondo;Hironori Kondo;Shinji Nakane;Tomoko Kodaka

  222
  Citations

• Detection of an Endogenous Cannabimimetic Molecule, 2-Arachidonoylglycerol, and Cannabinoid CB1 Receptor mRNA in Human Vascular Cells: Is 2-Arachidonoylglycerol a Possible Vasomodulator? ☆ ☆☆

  Takayuki Sugiura;Tomoko Kodaka;Shinji Nakane;Seishi Kishimoto

  207
  Citations

• IS THE CANNABINOID CB1 RECEPTOR A 2-ARACHIDONOYLGLYCEROL RECEPTOR? STRUCTURAL REQUIREMENTS FOR TRIGGERING A CA2+ TRANSIENT IN NG108-15 CELLS

  Takayuki Sugiura;Tomoko Kodaka;Sachiko Kondo;Shinji Nakane

  194
  Citations

• 2-arachidonoylglycerol induces the migration of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism.

  Seishi Kishimoto;Maiko Gokoh;Saori Oka;Mayumi Muramatsu

  181
  Citations