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Neuroscience
Canada
2026
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Medicine
Canada
2023

D-Index & Metrics

Neuroscience

D-Index
127
Citations
60263
World Ranking
308
National Ranking
8

Medicine

D-Index
127
Citations
60762
World Ranking
2825
National Ranking
112

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Canada Leader Award
  • 2025 - Research.com Neuroscience in Canada Leader Award
  • 2023 - Research.com Medicine in Canada Leader Award

Overview

Douglas L. Arnold is affiliated with the Montreal Neurological Institute and Hospital in Canada. Their research primarily focuses on Medicine with a significant emphasis on subfields such as Pathology and Forensic Medicine, Radiology, Nuclear Medicine and Imaging, Neurology, Oncology, and Rheumatology.

Their scholarly work extensively covers topics including Multiple Sclerosis Research Studies, Polyomavirus and related diseases, Chronic Lymphocytic Leukemia Research, Peripheral Neuropathies and Disorders, Rheumatoid Arthritis Research and Therapies, Chronic Myeloid Leukemia Treatments, and Radiomics and Machine Learning in Medical Imaging.

Douglas L. Arnold has published numerous articles in various scientific venues. Frequent publication venues include:

  • Neurology
  • Multiple Sclerosis Journal
  • Multiple Sclerosis and Related Disorders
  • arXiv (Cornell University)
  • Revue Neurologique

Their recent papers highlight ongoing research in neurological disorders, especially related to multiple sclerosis. Notable papers include:

  • Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials, 2020, JAMA Neurology
  • How patients with multiple sclerosis acquire disability, 2022, Brain
  • Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data, 2021, Nature Communications
  • Secondary Progressive Multiple Sclerosis, 2021, Neurology
  • Safety and efficacy of tolebrutinib, an oral brain-penetrant BTK inhibitor, in relapsing multiple sclerosis: a phase 2b, randomised, double-blind, placebo-controlled trial, 2021, The Lancet Neurology

The scientist collaborates frequently with other researchers in the field. Frequent co-authors include:

  • Amit Bar-Or
  • Ludwig Kappos
  • Xavier Montalbán
  • Sridar Narayanan
  • Bruce Cree

Best Publications

  • B-cell depletion with rituximab in relapsing-remitting multiple sclerosis.

    Stephen L. Hauser;Emmanuelle Waubant;Douglas L. Arnold;Timothy Vollmer

  • Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis.

    Stephen L. Hauser;Amit Bar-Or;Giancarlo Comi;Gavin Giovannoni

  • Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis

    Ralf Gold;Ludwig Kappos;Douglas L Arnold;Amit Bar-Or

  • Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

    Xavier Montalban;Stephen L. Hauser;Ludwig Kappos;Douglas L. Arnold

  • Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial.

    Jeffrey A. Cohen;Alasdair J. Coles;Douglas L. Arnold;Christian Confavreux

  • Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: A randomised controlled phase 3 trial

    Alasdair J. Coles;Cary L. Twyman;Douglas L. Arnold;Jeffrey A. Cohen

  • Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

    Unknown

  • Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy.

    Preul Mc;Caramanos Z;Collins Dl;Villemure Jg

  • Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability.

    Nicola De Stefano;Sridar Narayanan;Gordon S. Francis;Rozie Arnaoutelis

  • Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trial.

    Amit Bar-Or;Peter A. J. Calabresi;Douglas Arnold;Clyde Markowitz

  • Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study.

    N De Stefano;P M Matthews;L Fu;S Narayanan

  • Imaging axonal damage of normal-appearing white matter in multiple sclerosis.

    L Fu;P M Matthews;N De Stefano;K J Worsley

  • Mesial temporal damage in temporal lobe epilepsy: a volumetric MRI study of the hippocampus, amygdala and parahippocampal region.

    N Bernasconi;A Bernasconi;Z Caramanos;S B Antel

  • Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials.

    Ludwig Kappos;Jerry S. Wolinsky;Gavin Giovannoni;Douglas L. Arnold

  • Metabolic recovery after exercise and the assessment of mitochondrial function in vivo in human skeletal muscle by means of 31P NMR.

    D. L. Arnold;P. M. Matthews;G. K. Radda

  • Reversible decreases in N-acetylaspartate after acute brain injury.

    Nicola De Stefano;Paul M. Matthews;Douglas L. Arnold;Douglas L. Arnold

  • How patients with multiple sclerosis acquire disability

    Unknown

  • Pegylated interferon beta-1a for relapsing-remitting multiple sclerosis (ADVANCE): a randomised, phase 3, double-blind study

    Peter A Calabresi;Bernd C Kieseier;Douglas L Arnold;Laura J Balcer

  • Review of automatic segmentation methods of multiple sclerosis white matter lesions on conventional magnetic resonance imaging.

    Daniel García-Lorenzo;Simon J. Francis;Sridar Narayanan;Douglas L. Arnold

  • Exploring uncertainty measures in deep networks for Multiple sclerosis lesion detection and segmentation.

    Tanya Nair;Doina Precup;Douglas L. Arnold;Tal Arbel

  • Evidence for adaptive functional changes in the cerebral cortex with axonal injury from multiple sclerosis.

    H Reddy;S Narayanan;R Arnoutelis;M Jenkinson

  • Chemical pathology of acute demyelinating lesions and its correlation with disability

    N De Stefano;P M Matthews;P M Matthews;J P Antel;M Preul

Frequent Co-Authors

Amit Bar-Or
Amit Bar-Or University of Pennsylvania
Sridar Narayanan
Sridar Narayanan Montreal Neurological Institute and Hospital
Krzysztof Selmaj
Krzysztof Selmaj University of Warmia and Mazury in Olsztyn
Eva Havrdova
Eva Havrdova Charles University
Brenda Banwell
Brenda Banwell Children's Hospital of Philadelphia
Ludwig Kappos
Ludwig Kappos University Hospital of Basel
Gavin Giovannoni
Gavin Giovannoni Queen Mary University of London
Paul M. Matthews
Paul M. Matthews Imperial College London
D. Louis Collins
D. Louis Collins McGill University
Hans-Peter Hartung
Hans-Peter Hartung Heinrich Heine University Düsseldorf

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