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Biology and Biochemistry

D-Index
56
Citations
17380
World Ranking
14181
National Ranking
1004

Overview

Kohji Takei is a researcher affiliated with Okayama University in Japan. Their work spans several fields within the life sciences, with primary focus areas including biochemistry, genetics, molecular biology, and medicine. Their research contributions touch upon numerous subfields such as cell biology, molecular biology, physiology, cellular and molecular neuroscience, and cardiology and cardiovascular medicine.

The scientist's research topics cover a range of biological and medical subjects, among which are:

  • Cellular transport and secretion
  • Microtubule and mitosis dynamics
  • Renal diseases and glomerulopathies
  • Pancreatic function and diabetes
  • Wnt/β-catenin signaling in development and cancer
  • Genetic neurodegenerative diseases
  • Erythrocyte function and pathophysiology

Kohji Takei has contributed to scholarly publications in various scientific venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Preprints.org
  • Journal of Biological Chemistry
  • The FASEB Journal
  • Communications Biology

Recent papers authored or co-authored by Kohji Takei include:

  • "Mutant BIN1-Dynamin 2 complexes dysregulate membrane remodeling in the pathogenesis of centronuclear myopathy," 2021, Journal of Biological Chemistry
  • "Dynamin 1 is important for microtubule organization and stabilization in glomerular podocytes," 2020, The FASEB Journal
  • "JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes," 2021, Communications Biology
  • "The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes," 2022, Frontiers in Cell and Developmental Biology
  • "Pacsin 2-dependent N-cadherin internalization regulates the migration behaviour of malignant cancer cells," 2023, Journal of Cell Science

Their collaborative research is supported by frequent partnerships with several co-authors, including:

  • Hiroshi Yamada
  • Tadashi Abe
  • Tetsuya Takeda
  • Kenshiro Fujise
  • Eizo Takashima

Best Publications

  • Essential Role of Phosphoinositide Metabolism in Synaptic Vesicle Recycling

    Ottavio Cremona;Ottavio Cremona;Gilbert Di Paolo;Markus R Wenk;Anita Lüthi

  • Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

    Kohji Takei;Peter S. McPherson;Sandra L. Schmid;Pietro De Camilli

  • Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis.

    Kohji Takei;Vladimir I. Slepnev;Volker Haucke;Pietro De Camilli

  • Generation of high curvature membranes mediated by direct endophilin bilayer interactions

    Khashayar Farsad;Niels Ringstad;Kohji Takei;Scott R. Floyd

  • Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

    Hong Chen;Silvia Fre;Vladimir I. Slepnev;Maria Rosaria Capua

  • Synapsins: Mosaics of Shared and Individual Domains in a Family of Synaptic Vesicle Phosphoproteins

    Thomas C. Südhof;Andrew J. Czernik;Hung Teh Kao;Kohji Takei

  • The role of Rab3A in neurotransmitter release

    Martin Geppert;Vadim Y. Bolshakov;Steven A. Siegelbaum;Kohji Takei

  • Synaptic vesicle endocytosis impaired by disruption of dynamin-SH3 domain interactions.

    Oleg Shupliakov;Oleg Shupliakov;Peter Löw;Peter Löw;Detlev Grabs;Detlev Grabs;Helge Gad;Helge Gad

  • The synaptic vesicle cycle: a single vesicle budding step involving clathrin and dynamin.

    K Takei;O Mundigl;L Daniell;P De Camilli

  • CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

    Xiao Jian Han;Yun Fei Lu;Shun Ai Li;Taku Kaitsuka

  • GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

    A Reetz;M Solimena;M Matteoli;F Folli

  • Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice.

    Shun Ai Li;Masami Watanabe;Hiroshi Yamada;Atsushi Nagai

  • A Functional Link between Dynamin and the Actin Cytoskeleton at Podosomes

    Gian-Carlo Ochoa;Vladimir I. Slepnev;Lynn Neff;Niels Ringstad

  • Generation of Coated Intermediates of Clathrin-Mediated Endocytosis on Protein-Free Liposomes

    Kohji Takei;Volker Haucke;Vladimir Slepnev;Khashayar Farsad

  • Clathrin-mediated endocytosis: membrane factors pull the trigger

    Kohji Takei;Volker Haucke

  • Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons.

    M Matteoli;K Takei;M S Perin;T C Südhof

  • Long-term treatment with the sodium glucose cotransporter 2 inhibitor, dapagliflozin, ameliorates glucose homeostasis and diabetic nephropathy in db/db mice.

    Naoto Terami;Daisuke Ogawa;Hiromi Tachibana;Takashi Hatanaka

  • ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Iγ

    Michael Krauss;Masahiro Kinuta;Markus R. Wenk;Pietro De Camilli

  • rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin.

    E P Garcia;P S McPherson;T J Chilcote;K Takei

  • Molecular Mechanisms in Synaptic Vesicle Endocytosis and Recycling

    Pietro De Camilli;Kohji Takei

Frequent Co-Authors

Hiroshi Yamada
Hiroshi Yamada Okayama University
Pietro De Camilli
Pietro De Camilli Yale University
Kazuhito Tomizawa
Kazuhito Tomizawa Kumamoto University
Peter S. McPherson
Peter S. McPherson Montreal Neurological Institute and Hospital
Thomas C. Südhof
Thomas C. Südhof Stanford University
Pier Paolo Di Fiore
Pier Paolo Di Fiore University of Milan
Yoshiya Oda
Yoshiya Oda Eisai (Japan)
Reinhard Jahn
Reinhard Jahn Max Planck Society
Volker Haucke
Volker Haucke Freie Universität Berlin

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