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Neuroscience

D-Index
45
Citations
17064
World Ranking
6797
National Ranking
2939

Overview

William T. Dauer is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research contributions lie primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on Neurology and Molecular Biology among the subfields.

The scientist's work spans multiple specialized areas, including Neurological disorders and treatments, Genetic Neurodegenerative Diseases, Nuclear Structure and Function, RNA Research and Splicing, Advanced Neuroimaging Techniques and Applications, Parkinson's Disease Mechanisms and Treatments, and Genetics and Neurodevelopmental Disorders.

Dauer has co-authored publications with several frequent collaborators, including Samuel S. Pappas, Sumin Kim, Dhananjay Yellajoshyula, Nicolaas I. Bohnen, and Jay Li. These collaborations highlight multidisciplinary approaches in tackling complex neurological and genetic conditions.

Publications by William T. Dauer have appeared in a variety of venues, with a concentration in journals such as bioRxiv (Cold Spring Harbor Laboratory), Brain Communications, Movement Disorders, JCI Insight, and Neurology.

  • Focused ultrasound using a novel targeting method four-tract tractography for magnetic resonance-guided high-intensity focused ultrasound targeting (2022, Brain Communications)
  • Discussion of Research Priorities for Gait Disorders in Parkinson's Disease (2021, Movement Disorders)
  • TorsinA restoration in a mouse model identifies a critical therapeutic window for DYT1 dystonia (2021, Journal of Clinical Investigation)
  • CNS critical periods: implications for dystonia and other neurodevelopmental disorders (2021, JCI Insight)
  • α4β2 * Nicotinic Cholinergic Receptor Target Engagement in Parkinson Disease Gait-Balance Disorders (2021, Annals of Neurology)

This selection of recent papers shows an emphasis on neurological disorders such as dystonia and Parkinson's disease, with investigative techniques ranging from molecular biology to advanced neuroimaging and therapeutic interventions.

Best Publications

  • Parkinson's disease: Mechanisms and models

    William T. Dauer;Serge Przedborski

  • Dopamine-modified α-synuclein blocks chaperone-mediated autophagy

    Marta Martinez-Vicente;Zsolt Talloczy;Susmita Kaushik;Ashish C. Massey

  • Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

    William Dauer;Nikolai Kholodilov;Miquel Vila;Anne Cecile Trillat

  • Interplay of LRRK2 with chaperone-mediated autophagy

    Samantha J. Orenstein;Sheng-Hang Kuo;Inmaculada Tasset;Esperanza Arias

  • Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice

    Noelia V. Weisstaub;Mingming Zhou;Alena Lira;Evelyn Lambe;Evelyn Lambe

  • Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope.

    Rose E. Goodchild;Connie Eunji Kim;William T. Dauer

  • A Critical Evaluation of The Braak Staging Scheme for Parkinson’s Disease

    Robert E. Burke;William T. Dauer;Jean Paul G. Vonsattel

  • The kinase domain of mitochondrial PINK1 faces the cytoplasm

    Chun Zhou;Yong Huang;Yufang Shao;Jessica May

  • Current concepts on the clinical features, aetiology and management of idiopathic cervical dystonia.

    William T. Dauer;Robert E. Burke;Paul Greene;Stanley Fahn

  • Mislocalization to the nuclear envelope: An effect of the dystonia-causing torsinA mutation

    Rose E. Goodchild;William T. Dauer

  • The Nuclear Envelope as a Signaling Node in Development and Disease

    William T. Dauer;Howard J. Worman

  • The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein

    Rose E. Goodchild;William T. Dauer

  • α-Synuclein produces a long-lasting increase in neurotransmitter release

    Shumin Liu;Ipe Ninan;Irina Antonova;Fortunato Battaglia

  • Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia

    Vikram G. Shakkottai;Amit Batla;Kailash Bhatia;William T. Dauer

  • LRRK2 Parkinson disease mutations enhance its microtubule association.

    Lauren R. Kett;Daniela Boassa;Cherry Cheng Ying Ho;Hardy J. Rideout

  • Model-based and Model-free Machine Learning Techniques for Diagnostic Prediction and Classification of Clinical Outcomes in Parkinson's Disease.

    Chao Gao;Hanbo Sun;Tuo Wang;Ming Tang

  • Primary dystonia: molecules and mechanisms

    Lauren M. Tanabe;Connie E. Kim;Noga Alagem;William T. Dauer

  • Cholinergic system changes of falls and freezing of gait in Parkinson's disease.

    Nicolaas I. Bohnen;Prabesh Kanel;Zhi Zhou;Robert A. Koeppe

  • A molecular mechanism underlying the neural-specific defect in torsinA mutant mice

    Connie E. Kim;Alex Perez;Guy Perkins;Mark H. Ellisman

  • TorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegeneration

    Chun Chi Liang;Lauren M. Tanabe;Stephanie Jou;Frank Chi

  • Cerebellothalamocortical pathway abnormalities in torsinA DYT1 knock-in mice

    Aziz M. Uluğ;An Vo;Miklos Argyelan;Lauren Tanabe

  • Thymidine kinase 2 (H126N) knockin mice show the essential role of balanced deoxynucleotide pools for mitochondrial DNA maintenance

    Hasan O. Akman;Beatriz Dorado;Luis C. López;Ángeles García-Cazorla

Frequent Co-Authors

Nicolaas I. Bohnen
Nicolaas I. Bohnen University of Michigan–Ann Arbor
Martijn L.T.M. Müller
Martijn L.T.M. Müller University of Michigan–Ann Arbor
Robert A. Koeppe
Robert A. Koeppe University of Michigan–Ann Arbor
Robert E. Burke
Robert E. Burke Columbia University
Serge Przedborski
Serge Przedborski Columbia University
Martin Sarter
Martin Sarter University of Michigan–Ann Arbor
David Sulzer
David Sulzer Columbia University
Kirk A. Frey
Kirk A. Frey University of Michigan–Ann Arbor
Mark R. Cookson
Mark R. Cookson National Institutes of Health
Ana Maria Cuervo
Ana Maria Cuervo Albert Einstein College of Medicine

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