D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 7,891 269 World Ranking 12231 National Ranking 900

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Masaharu Seno spends much of his time researching Molecular biology, Biochemistry, Betacellulin, Cell biology and Internal medicine. His Molecular biology research includes elements of Epithelial–mesenchymal transition, Hepadnaviridae, Virus, Messenger RNA and Antibody. His Cell biology research integrates issues from Cripto, NODAL and Cellular differentiation.

His Cellular differentiation study combines topics in areas such as Cancer research, Cancer stem cell, Induced pluripotent stem cell, Anti-apoptotic Ras signalling cascade and SMAD. Masaharu Seno studied Internal medicine and Endocrinology that intersect with Regeneration. His Insulin study combines topics from a wide range of disciplines, such as Cell culture and Pancreas.

His most cited work include:

  • Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells. (271 citations)
  • Nanoparticles for the delivery of genes and drugs to human hepatocytes. (227 citations)
  • Identification of the motility-related protein (MRP-1), recognized by monoclonal antibody M31-15, which inhibits cell motility. (180 citations)

What are the main themes of his work throughout his whole career to date?

Masaharu Seno mainly investigates Cancer research, Cancer stem cell, Molecular biology, Induced pluripotent stem cell and Cell biology. His Cancer research research includes themes of Tumor microenvironment, Cancer, Cell culture, CD44 and In vivo. His study explores the link between Cancer stem cell and topics such as Homeobox protein NANOG that cross with problems in SOX2.

His Molecular biology research incorporates themes from Cell, Basic fibroblast growth factor, Antigen, Complementary DNA and Fusion protein. His studies in Cell biology integrate themes in fields like Cripto, Epidermal growth factor and Cellular differentiation. Masaharu Seno has researched Epidermal growth factor in several fields, including Endocrinology, Receptor tyrosine kinase and ErbB.

He most often published in these fields:

  • Cancer research (34.42%)
  • Cancer stem cell (30.80%)
  • Molecular biology (22.83%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (34.42%)
  • Cancer stem cell (30.80%)
  • Induced pluripotent stem cell (22.46%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cancer research, Cancer stem cell, Induced pluripotent stem cell, Cancer cell and Cancer. The study incorporates disciplines such as Cell culture, CD44, Tumor microenvironment, Immune system and Homeobox protein NANOG in addition to Cancer research. His Cancer stem cell research is multidisciplinary, relying on both Carcinogenesis, Paclitaxel, Metastasis and In vivo.

His Induced pluripotent stem cell study integrates concerns from other disciplines, such as Lewis lung carcinoma, Transplantation, Sorafenib and Cell biology. His work in Cell biology addresses subjects such as Epidermal growth factor, which are connected to disciplines such as Signal transduction. His Cancer cell research incorporates elements of Heat shock protein, Tumor progression, Cripto and Gene knockdown.

Between 2017 and 2021, his most popular works were:

  • HSP-enriched properties of extracellular vesicles involve survival of metastatic oral cancer cells (53 citations)
  • Conversion of Stem Cells to Cancer Stem Cells: Undercurrent of Cancer Initiation (40 citations)
  • Targeting Glioblastoma Cells Expressing CD44 with Liposomes Encapsulating Doxorubicin and Displaying Chlorotoxin-IgG Fc Fusion Protein. (16 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Masaharu Seno focuses on Cancer research, Cancer stem cell, Induced pluripotent stem cell, Stem cell and Cancer cell. Masaharu Seno interconnects Cancer, Metastasis, CD44, Homeobox protein NANOG and In vivo in the investigation of issues within Cancer research. His Cancer study incorporates themes from Differentially methylated regions, DNA methylation, Epigenetics and Cellular differentiation.

Masaharu Seno combines subjects such as Cell culture and Mitotic catastrophe, DNA damage with his study of Stem cell. His study in Cell culture is interdisciplinary in nature, drawing from both Liver cancer, Hepatocellular carcinoma and Molecular mechanism. His work deals with themes such as Tumor microenvironment, CD34, Bone marrow and Heat shock protein, which intersect with Cancer cell.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells.

Hirosato Mashima;Hirohide Ohnishi;Katsumi Wakabayashi;Tetsuya Mine.
Journal of Clinical Investigation (1996)

358 Citations

Nanoparticles for the delivery of genes and drugs to human hepatocytes

Tadanori Yamada;Yasushi Iwasaki;Hiroko Tada;Hidehiko Iwabuki.
Nature Biotechnology (2003)

335 Citations

Identification of the motility-related protein (MRP-1), recognized by monoclonal antibody M31-15, which inhibits cell motility.

Masayuki Miyake;Masaru Koyama;Masaharu Seno;Shuichi Ikeyama.
Journal of Experimental Medicine (1991)

244 Citations

Combined Expression of Pancreatic Duodenal Homeobox 1 and Islet Factor 1 Induces Immature Enterocytes to Produce Insulin

Hideto Kojima;Takaaki Nakamura;Yukihiro Fujita;Akio Kishi.
Diabetes (2002)

210 Citations

Stabilizing basic fibroblast growth factor using protein engineering.

Masaharu Seno;Reiko Sasada;Makoto Iwane;Katsuichi Sudo.
Biochemical and Biophysical Research Communications (1988)

181 Citations

The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.

D S Saloman;C Bianco;A D Ebert;N I Khan.
Endocrine-related Cancer (2000)

177 Citations

Activin A and Betacellulin: Effect on Regeneration of Pancreatic β-Cells in Neonatal Streptozotocin-Treated Rats

Lei Li;Zhaohong Yi;Masaharu Seno;Itaru Kojima.
Diabetes (2004)

175 Citations

Cripto-1 Activates Nodal- and ALK4-Dependent and -Independent Signaling Pathways in Mammary Epithelial Cells

Caterina Bianco;Heather B. Adkins;Heather B. Adkins;Christian Wechselberger;Masaharu Seno.
Molecular and Cellular Biology (2002)

175 Citations

Epithelial mesenchymal transition is a characteristic of hyperplasias and tumors in mammary gland from MMTV-Cripto-1 transgenic mice.

Luigi Strizzi;Caterina Bianco;Nicola Normanno;Masaharu Seno.
Journal of Cellular Physiology (2004)

174 Citations

Tissue-specific expression of pancreatic-type RNases and RNase inhibitor in humans.

Junichiro Futami;Yoshiaki Tsushima;Yu Murato;Hiroko Tada.
DNA and Cell Biology (1997)

131 Citations

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