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Masakiyo Sakaguchi

Masakiyo Sakaguchi

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9941
World Ranking
15680
National Ranking
1114

Overview

Masakiyo Sakaguchi is a researcher affiliated with Okayama University in Japan. They have focused extensively on fields related to Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to Molecular Biology, Pulmonary and Respiratory Medicine, Immunology, Oncology, and Cancer Research.

Their research encompasses a range of topics, including:

  • S100 Proteins and Annexins
  • Cell Adhesion Molecules Research
  • Neonatal Respiratory Health Research
  • Immune Response and Inflammation
  • Cancer Cells and Metastasis
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Protease and Inhibitor Mechanisms

Masakiyo Sakaguchi has published extensively in several journals. Their frequent publication venues include:

  • Frontiers in Oncology
  • In Vitro Cellular & Developmental Biology - Animal
  • International Journal of Molecular Sciences
  • Journal of Molecular Medicine
  • Biochemical and Biophysical Research Communications

Notable papers authored or co-authored by Masakiyo Sakaguchi include:

  • The heterodimer S100A8/A9 is a potent therapeutic target for idiopathic pulmonary fibrosis, 2020, Journal of Molecular Medicine
  • MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by ROS1 Fusions, 2020, Clinical Cancer Research
  • Histidine-Rich Glycoprotein Inhibits High-Mobility Group Box-1-Mediated Pathways in Vascular Endothelial Cells through CLEC-1A, 2020, iScience
  • PLOD2 Is Essential to Functional Activation of Integrin β1 for Invasion/Metastasis in Head and Neck Squamous Cell Carcinomas, 2020, iScience
  • SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells, 2023, International Journal of Molecular Sciences

Collaborations have been an integral part of their research efforts. Frequent co-authors working with Masakiyo Sakaguchi include:

  • Nahoko Tomonobu
  • Rie Kinoshita
  • Hitoshi Murata
  • Shinichi Toyooka
  • Ni Luh Gede Yoni Komalasari

Best Publications

  • Prevention of Acute Liver Failure in Rats with Reversibly Immortalized Human Hepatocytes

    Naoya Kobayashi;Toshiyoshi Fujiwara;Karen A. Westerman;Yusuke Inoue

  • Hepatocyte growth factor induces differentiation of adult rat bone marrow cells into a hepatocyte lineage in vitro.

    Seh Hoon Oh;Masahiro Miyazaki;Hirosuke Kouchi;Yusuke Inoue

  • TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding.

    Masakiyo Sakaguchi;Hitoshi Murata;Ken ichi Yamamoto;Tomoyuki Ono

  • Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase.

    Fernando Abarzua;Masakiyo Sakaguchi;Mikiro Takaishi;Yasutomo Nasu

  • A REIC Gene Shows Down-Regulation in Human Immortalized Cells and Human Tumor-Derived Cell Lines

    Toshiya Tsuji;Masahiro Miyazaki;Masakiyo Sakaguchi;Yusuke Inoue

  • S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells

    Jyoti K. Jaiswal;Stine P. Lauritzen;Luana Scheffer;Masakiyo Sakaguchi

  • S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis.

    Toshihiko Hibino;Masakiyo Sakaguchi;Shoko Miyamoto;Mami Yamamoto

  • NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions

    Hitoshi Murata;Hitoshi Takamatsu;Sulai Liu;Ken Kataoka

  • Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas.

    Toshiya Tsuji;Isao Nozaki;Masahiro Miyazaki;Masakiyo Sakaguchi

  • ESTABLISHMENT OF A HIGHLY DIFFERENTIATED IMMORTALIZED HUMAN CHOLANGIOCYTE CELL LINE WITH SV40T AND hTERT

    Masanobu Maruyama;Naoya Kobayashi;Karen A. Westerman;Masakiyo Sakaguchi

  • S100C/A11 is a key mediator of Ca2+-induced growth inhibition of human epidermal keratinocytes

    Masakiyo Sakaguchi;Masahiro Miyazaki;Mikiro Takaishi;Yoshihiko Sakaguchi

  • A New Cytosolic Pathway from a Parkinson Disease-associated Kinase, BRPK/PINK1 ACTIVATION OF AKT VIA MTORC2

    Hitoshi Murata;Masakiyo Sakaguchi;Yu Jin;Yoshihiko Sakaguchi

  • S100A8/A9, a key mediator for positive feedback growth stimulation of normal human keratinocytes†

    Takamasa Nukui;Ritsuko Ehama;Masakiyo Sakaguchi;Hiroyuki Sonegawa

  • Decreased Expression of REIC/Dkk-3 in Human Renal Clear Cell Carcinoma

    Kyouhei Kurose;Masakiyo Sakaguchi;Yasutomo Nasu;Shin Ebara

  • Relationship between Contact Inhibition and Intranuclear S100c of Normal Human Fibroblasts

    Masakiyo Sakaguchi;Masahiro Miyazaki;Yusuke Inoue;Toshiya Tsuji

  • Epigenetic Silencing of MicroRNA-34b/c Plays an Important Role in the Pathogenesis of Malignant Pleural Mesothelioma

    Takafumi Kubo;Shinichi Toyooka;Kazunori Tsukuda;Masakiyo Sakaguchi

  • Intracellular Delivery of Proteins into Mammalian Living Cells by Polyethylenimine-Cationization

    Junichiro Futami;Midori Kitazoe;Takashi Maeda;Emiko Nukui

  • Improved conditions to induce hepatocytes from rat bone marrow cells in culture.

    Masahiro Miyazaki;Ichiro Akiyama;Masakiyo Sakaguchi;Emiko Nakashima

  • Novel Germline Mutation in the Transmembrane Domain of HER2 in Familial Lung Adenocarcinomas

    Hiromasa Yamamoto;Koichiro Higasa;Masakiyo Sakaguchi;Kazuhiko Shien

  • Down-regulation of inhibition of differentiation-1 via activation of activating transcription factor 3 and Smad regulates REIC/Dickkopf-3-induced apoptosis.

    Yuji Kashiwakura;Kazuhiko Ochiai;Masami Watanabe;Fernando Abarzua

Frequent Co-Authors

Shinichi Toyooka
Shinichi Toyooka Okayama University
Masahiro Nishibori
Masahiro Nishibori Okayama University
Noriaki Tanaka
Noriaki Tanaka Okayama University
Akira Yamauchi
Akira Yamauchi Kawasaki Medical School
Philippe Leboulch
Philippe Leboulch Brigham and Women's Hospital
Toshiyoshi Fujiwara
Toshiyoshi Fujiwara Okayama University
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Keiji Iwatsuki
Keiji Iwatsuki Okayama University
Keitaro Matsuo
Keitaro Matsuo Nagoya University
Masaharu Seno
Masaharu Seno Okayama University

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