World's Best Scientists 2026 revealed!
Masakiyo Sakaguchi

Masakiyo Sakaguchi

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9941
World Ranking
15680
National Ranking
1114

Masakiyo Sakaguchi publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Masakiyo Sakaguchi sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 256 publications — 69th percentile

69% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Masakiyo Sakaguchi D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Masakiyo Sakaguchi sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 54 D-Index — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Masakiyo Sakaguchi is a researcher affiliated with Okayama University in Japan. They have focused extensively on fields related to Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to Molecular Biology, Pulmonary and Respiratory Medicine, Immunology, Oncology, and Cancer Research.

Their research encompasses a range of topics, including:

  • S100 Proteins and Annexins
  • Cell Adhesion Molecules Research
  • Neonatal Respiratory Health Research
  • Immune Response and Inflammation
  • Cancer Cells and Metastasis
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Protease and Inhibitor Mechanisms

Masakiyo Sakaguchi has published extensively in several journals. Their frequent publication venues include:

  • Frontiers in Oncology
  • In Vitro Cellular & Developmental Biology - Animal
  • International Journal of Molecular Sciences
  • Journal of Molecular Medicine
  • Biochemical and Biophysical Research Communications

Notable papers authored or co-authored by Masakiyo Sakaguchi include:

  • The heterodimer S100A8/A9 is a potent therapeutic target for idiopathic pulmonary fibrosis, 2020, Journal of Molecular Medicine
  • MAPK Pathway Alterations Correlate with Poor Survival and Drive Resistance to Therapy in Patients with Lung Cancers Driven by ROS1 Fusions, 2020, Clinical Cancer Research
  • Histidine-Rich Glycoprotein Inhibits High-Mobility Group Box-1-Mediated Pathways in Vascular Endothelial Cells through CLEC-1A, 2020, iScience
  • PLOD2 Is Essential to Functional Activation of Integrin β1 for Invasion/Metastasis in Head and Neck Squamous Cell Carcinomas, 2020, iScience
  • SPRED2: A Novel Regulator of Epithelial-Mesenchymal Transition and Stemness in Hepatocellular Carcinoma Cells, 2023, International Journal of Molecular Sciences

Collaborations have been an integral part of their research efforts. Frequent co-authors working with Masakiyo Sakaguchi include:

  • Nahoko Tomonobu
  • Rie Kinoshita
  • Hitoshi Murata
  • Shinichi Toyooka
  • Ni Luh Gede Yoni Komalasari

Best Publications

  • Prevention of Acute Liver Failure in Rats with Reversibly Immortalized Human Hepatocytes

    Naoya Kobayashi;Toshiyoshi Fujiwara;Karen A. Westerman;Yusuke Inoue

  • Hepatocyte growth factor induces differentiation of adult rat bone marrow cells into a hepatocyte lineage in vitro.

    Seh Hoon Oh;Masahiro Miyazaki;Hirosuke Kouchi;Yusuke Inoue

  • TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding.

    Masakiyo Sakaguchi;Hitoshi Murata;Ken ichi Yamamoto;Tomoyuki Ono

  • Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-kinase.

    Fernando Abarzua;Masakiyo Sakaguchi;Mikiro Takaishi;Yasutomo Nasu

  • A REIC Gene Shows Down-Regulation in Human Immortalized Cells and Human Tumor-Derived Cell Lines

    Toshiya Tsuji;Masahiro Miyazaki;Masakiyo Sakaguchi;Yusuke Inoue

  • S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells

    Jyoti K. Jaiswal;Stine P. Lauritzen;Luana Scheffer;Masakiyo Sakaguchi

  • S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis.

    Toshihiko Hibino;Masakiyo Sakaguchi;Shoko Miyamoto;Mami Yamamoto

  • NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions

    Hitoshi Murata;Hitoshi Takamatsu;Sulai Liu;Ken Kataoka

  • Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas.

    Toshiya Tsuji;Isao Nozaki;Masahiro Miyazaki;Masakiyo Sakaguchi

  • ESTABLISHMENT OF A HIGHLY DIFFERENTIATED IMMORTALIZED HUMAN CHOLANGIOCYTE CELL LINE WITH SV40T AND hTERT

    Masanobu Maruyama;Naoya Kobayashi;Karen A. Westerman;Masakiyo Sakaguchi

  • S100C/A11 is a key mediator of Ca2+-induced growth inhibition of human epidermal keratinocytes

    Masakiyo Sakaguchi;Masahiro Miyazaki;Mikiro Takaishi;Yoshihiko Sakaguchi

  • A New Cytosolic Pathway from a Parkinson Disease-associated Kinase, BRPK/PINK1 ACTIVATION OF AKT VIA MTORC2

    Hitoshi Murata;Masakiyo Sakaguchi;Yu Jin;Yoshihiko Sakaguchi

  • S100A8/A9, a key mediator for positive feedback growth stimulation of normal human keratinocytes†

    Takamasa Nukui;Ritsuko Ehama;Masakiyo Sakaguchi;Hiroyuki Sonegawa

  • Decreased Expression of REIC/Dkk-3 in Human Renal Clear Cell Carcinoma

    Kyouhei Kurose;Masakiyo Sakaguchi;Yasutomo Nasu;Shin Ebara

  • Relationship between Contact Inhibition and Intranuclear S100c of Normal Human Fibroblasts

    Masakiyo Sakaguchi;Masahiro Miyazaki;Yusuke Inoue;Toshiya Tsuji

  • Epigenetic Silencing of MicroRNA-34b/c Plays an Important Role in the Pathogenesis of Malignant Pleural Mesothelioma

    Takafumi Kubo;Shinichi Toyooka;Kazunori Tsukuda;Masakiyo Sakaguchi

  • Intracellular Delivery of Proteins into Mammalian Living Cells by Polyethylenimine-Cationization

    Junichiro Futami;Midori Kitazoe;Takashi Maeda;Emiko Nukui

  • Improved conditions to induce hepatocytes from rat bone marrow cells in culture.

    Masahiro Miyazaki;Ichiro Akiyama;Masakiyo Sakaguchi;Emiko Nakashima

  • Novel Germline Mutation in the Transmembrane Domain of HER2 in Familial Lung Adenocarcinomas

    Hiromasa Yamamoto;Koichiro Higasa;Masakiyo Sakaguchi;Kazuhiko Shien

  • Down-regulation of inhibition of differentiation-1 via activation of activating transcription factor 3 and Smad regulates REIC/Dickkopf-3-induced apoptosis.

    Yuji Kashiwakura;Kazuhiko Ochiai;Masami Watanabe;Fernando Abarzua

Frequent Co-Authors

Shinichi Toyooka
Shinichi Toyooka Okayama University
Masahiro Nishibori
Masahiro Nishibori Okayama University
Noriaki Tanaka
Noriaki Tanaka Okayama University
Akira Yamauchi
Akira Yamauchi Kawasaki Medical School
Philippe Leboulch
Philippe Leboulch Brigham and Women's Hospital
Toshiyoshi Fujiwara
Toshiyoshi Fujiwara Okayama University
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health
Keiji Iwatsuki
Keiji Iwatsuki Okayama University
Keitaro Matsuo
Keitaro Matsuo Nagoya University
Masaharu Seno
Masaharu Seno Okayama University

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