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D-Index & Metrics

Chemistry

D-Index
40
Citations
7651
World Ranking
17845
National Ranking
347

Overview

Chul-Ho Yun is affiliated with Chonnam National University in South Korea. Their research spans several interconnected fields including Biochemistry, Genetics and Molecular Biology as well as Pharmacology, Toxicology and Pharmaceutics. Within these domains, they have focused extensively on Pharmacology and Molecular Biology while also contributing to Biomaterials, Biomedical Engineering, and Computational Theory and Mathematics.

Their investigations cover main topics such as Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Microplastics and Plastic Pollution, biodegradable polymer synthesis and properties, Biochemical Analysis and Sensing Techniques, melanin and skin pigmentation, and Recycling and Waste Management Techniques.

Yun's recent published works include studies on biodegradation processes and biocatalysis. Notable papers are:

  • Light-driven biocatalytic oxidation (2022), Chemical Science
  • Biodegradation of polystyrene by bacteria from the soil in common environments (2021), Journal of Hazardous Materials
  • P450-driven plastic-degrading synthetic bacteria (2021), Trends in biotechnology
  • Screening of Human CYP1A2 and CYP3A4 Inhibitors from Seaweed In Silico and In Vitro (2020), Marine Drugs
  • Exploring a New Biocatalyst from Bacillus thuringiensis JNU01 for Polyethylene Biodegradation (2023), Environmental Science & Technology Letters

Throughout their career, Yun collaborated frequently with several researchers, including:

  • Gun Su
  • Soo-Jin Yeom
  • Hyung-Sik Kang
  • Chan Mi Park
  • Thien-Kim Le

Their work has been published repeatedly in venues such as:

  • Enzyme and Microbial Technology
  • ChemSusChem
  • Catalysts
  • Pharmaceuticals
  • Journal of Microbiology and Biotechnology

Best Publications

  • Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

    H. Yamazaki;Y. Inui;Chul-Ho Yun;F. P. Guengerich

  • Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat.

    M. Sattler;F. P. Guengerich;Chul-Ho Yun;U. Christians

  • Purification and characterization of human liver microsomal cytochrome P-450 2A6.

    Chul-Ho Yun;T. Shimada;F. P. Guengerich

  • Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens.

    T. Shimada;Chul-Ho Yun;H. Yamazaki;J.-C. Gautier

  • Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation.

    Chul-Ho Yun;R. A. Okerholm;F. P. Guengerich

  • Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megaterium.

    Ji-Yeon Kang;So-Young Kim;Dooil Kim;Dong-Hyun Kim

  • Evidence for a 1-Electron Oxidation Mechanism in N-Dealkylation of N,N-Dialkylanilines by Cytochrome P450 2B1 KINETIC HYDROGEN ISOTOPE EFFECTS, LINEAR FREE ENERGY RELATIONSHIPS, COMPARISONS WITH HORSERADISH PEROXIDASE, AND STUDIES WITH OXYGEN SURROGATES

    F P Guengerich;C H Yun;T L Macdonald

  • Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants.

    Yun Ch;Miller Gp;Guengerich Fp

  • Separation of human liver microsomal tolbutamide hydroxylase and (S)-mephenytoin 4'-hydroxylase cytochrome P-450 enzymes.

    P K Srivastava;C H Yun;P H Beaune;C Ged

  • Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance.

    Chul-Ho Yun;Margaret Wood;Alastair Wood;F. Guengerich

  • Biodegradation of polystyrene by bacteria from the soil in common environments

    Hyeong-Woo Kim;Jin Hui Jo;Ye-Bin Kim;Thien-Kim Le

  • Roles of human liver cytochrome P4502C and 3A enzymes in the 3-hydroxylation of benzo(a)pyrene.

    Chul-Ho Yun;T. Shimada;F. P. Guengerich

  • The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities

    Chul-Ho Yun;Keon-Hee Kim;Dong-Hyun Kim;Heung-Chae Jung

  • Cofactor‐Free Light‐Driven Whole‐Cell Cytochrome P450 Catalysis

    Jong Hyun Park;Sahng Ha Lee;Gun Su Cha;Da Som Choi

  • Purification and Characterization of Thiol-Specific Antioxidant Protein from Human Red Blood Cell: A New Type of Antioxidant Protein

    Yoo-Shick Lim;Mee-Kyung Cha;Chul-Ho Yun;Ha-Kun Kim

  • Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes

    Chul-Ho Yun;Hye Gwang Jeong;Jay Woo Jhoun;F. P. Guengerich

  • Oxidation of the angiotensin II receptor antagonist losartan (DuP 753) in human liver microsomes. Role of cytochrome P4503A(4) in formation of the active metabolite EXP3174.

    C H Yun;H S Lee;H Lee;J K Rho

  • P450-driven plastic-degrading synthetic bacteria.

    Soo-Jin Yeom;Thien-Kim Le;Chul-Ho Yun

  • Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes.

    F. P. Guengerich;T. Shimada;Chul-Ho Yun;H. Yamazaki

  • Kinetic Analysis of Oxidation of Coumarins by Human Cytochrome P450 2A6

    Chul-Ho Yun;Keon-Hee Kim;M. Wade Calcutt;F. Peter Guengerich

  • Generation of the Human Metabolite Piceatannol from the Anticancer-Preventive Agent Resveratrol by Bacterial Cytochrome P450 BM3

    Dong-Hyun Kim;Taeho Ahn;Heung-Chae Jung;Jae-Gu Pan

  • Functional expression of human cytochrome P450 enzymes in Escherichia coli.

    Chul-Ho Yun;Sung-Kun Yim;Dong-Hyun Kim;Taeho Ahn

Frequent Co-Authors

Dong-Hyun Kim
Dong-Hyun Kim Kyung Hee University
F. Peter Guengerich
F. Peter Guengerich Vanderbilt University
Han-Jung Chae
Han-Jung Chae Jeonbuk National University
Tsutomu Shimada
Tsutomu Shimada Osaka Metropolitan University
Chan Beum Park
Chan Beum Park Korea Advanced Institute of Science and Technology
Hiroshi Yamazaki
Hiroshi Yamazaki Showa Pharmaceutical University
Hye Gwang Jeong
Hye Gwang Jeong Chungnam National University
Jung-Kul Lee
Jung-Kul Lee Konkuk University
Jung-Soo Han
Jung-Soo Han Konkuk University
Thomas M. Harris
Thomas M. Harris Vanderbilt University

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