D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 57 Citations 13,726 176 World Ranking 2613 National Ranking 112

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

Thomas W.H. Kay spends much of his time researching Immunology, Internal medicine, Type 1 diabetes, Endocrinology and Insulitis. He interconnects Nod and Proinsulin in the investigation of issues within Immunology. His Type 1 diabetes research is multidisciplinary, incorporating elements of Pancreas transplantation and Islet, Insulin, Glycemic.

His Islet research incorporates elements of Apoptosis and Transplantation. Thomas W.H. Kay has researched Endocrinology in several fields, including Downregulation and upregulation and Transcription factor. His Insulitis study incorporates themes from CD8 and Major histocompatibility complex.

His most cited work include:

  • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. (1387 citations)
  • SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine (693 citations)
  • Improvement in outcomes of clinical islet transplantation: 1999-2010. (497 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Immunology, Internal medicine, Endocrinology, Islet and NOD mice. His Immunology study integrates concerns from other disciplines, such as Type 1 diabetes and Beta cell. His Internal medicine course of study focuses on Diabetes mellitus and Pancreas and Autoantibody.

His work carried out in the field of Endocrinology brings together such families of science as Proinflammatory cytokine and Signal transduction. The study incorporates disciplines such as Transplantation and Cell biology in addition to Islet. His NOD mice research is multidisciplinary, relying on both T cell and Cytokine.

He most often published in these fields:

  • Immunology (51.77%)
  • Internal medicine (37.17%)
  • Endocrinology (31.86%)

What were the highlights of his more recent work (between 2017-2021)?

  • Islet (36.73%)
  • Transplantation (27.43%)
  • Cell biology (26.99%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Islet, Transplantation, Cell biology, NOD mice and Type 1 diabetes. His research on Islet concerns the broader Internal medicine. His work deals with themes such as Diabetes mellitus, Endocrinology and Gastroenterology, which intersect with Internal medicine.

The various areas that he examines in his NOD mice study include T cell and CD8. His Type 1 diabetes research is multidisciplinary, incorporating perspectives in Proinsulin and Immunology, Immune system, Antigen. Thomas W.H. Kay integrates Immunology with Sting in his study.

Between 2017 and 2021, his most popular works were:

  • Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes (114 citations)
  • Proinsulin C-peptide is an autoantigen in people with type 1 diabetes. (29 citations)
  • Proinsulin C-peptide is an autoantigen in people with type 1 diabetes. (29 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

His scientific interests lie mostly in Type 1 diabetes, Transplantation, Islet, Diabetes mellitus and T cell. His Type 1 diabetes research includes themes of C-peptide, Immunology, Antigen, Proinsulin and Autoimmunity. The subject of his Islet research is within the realm of Insulin.

His Insulin research is under the purview of Internal medicine. His Internal medicine research includes elements of Endocrinology and Bioenergetics. As part of the same scientific family, Thomas W.H. Kay usually focuses on T cell, concentrating on NOD mice and intersecting with Cancer research, NFKB1 and NF-κB.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity.

Philippe Bouillet;Donald Metcalf;David C. S. Huang;David M. Tarlinton.
Science (1999)

1839 Citations

SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine

Warren S Alexander;Robyn Starr;Robyn Starr;Jennifer E Fenner;Clare L Scott;Clare L Scott.
Cell (1999)

907 Citations

Improvement in outcomes of clinical islet transplantation: 1999-2010.

Franca B. Barton;Michael R. Rickels;Rodolfo Alejandro;Bernhard J. Hering.
Diabetes Care (2012)

774 Citations

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

Ken T. Coppieters;Francesco Dotta;Natalie Amirian;Peter D. Campbell.
Journal of Experimental Medicine (2012)

611 Citations

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice.

I. L. Campbell;T. W. H. Kay;L. Oxbrow;L. C. Harrison.
Journal of Clinical Investigation (1991)

488 Citations

Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

Gregory r Steinberg;Belinda J Michell;Bryce J W Jw van Denderen;Matthew James Watt.
Cell Metabolism (2006)

488 Citations

Granulocyte Macrophage Colony-Stimulating Factor A New Putative Therapeutic Target in Multiple Sclerosis

Jonathan Luke McQualter;Rima Darwiche;Christine Ewing;Manabu Onuki.
Journal of Experimental Medicine (2001)

481 Citations

Transgenic Expression of Mouse Proinsulin II Prevents Diabetes in Nonobese Diabetic Mice

Michelle B French;Janette Allison;David S Cram;Helen E Thomas.
Diabetes (1997)

321 Citations

Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets

Kim Cheng;Kenneth Ho;Rebecca Stokes;Christopher Scott.
Journal of Clinical Investigation (2010)

254 Citations

Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

Balasubramanian Krishnamurthy;Nadine L. Dudek;Mark D. McKenzie;Anthony W. Purcell.
Journal of Clinical Investigation (2006)

250 Citations

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