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Leonard C. Harrison

Leonard C. Harrison

D-Index & Metrics

Immunology

D-Index
96
Citations
28984
World Ranking
867
National Ranking
30

Medicine

D-Index
97
Citations
29819
World Ranking
9404
National Ranking
285

Overview

Leonard C. Harrison is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research focuses predominantly on diabetes, its management, and associated disorders, with significant contributions in understanding pancreatic function and the role of gut microbiota in health.

Their main fields of study include Medicine and Biochemistry, Genetics and Molecular Biology. Within these broad disciplines, Harrison's work extends into subfields such as Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, Surgery, and Immunology.

Key research topics addressed by Harrison cover:

  • Diabetes and associated disorders
  • Diabetes Management and Research
  • Pancreatic function and diabetes
  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Adolescent and Pediatric Healthcare
  • Gestational Diabetes Research and Management

The scholar has contributed to multiple frequent publication venues, reflecting the focus and dissemination channels of their work. These venues include:

  • Diabetologia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetes Care
  • Pediatric Diabetes
  • Nature Communications

Among their recent papers are notable works:

  • "Baricitinib and β-Cell Function in Patients with New-Onset Type 1 Diabetes" (2023) published in New England Journal of Medicine
  • "Maternal carriage of Prevotella during pregnancy associates with protection against food allergy in the offspring" (2020) published in Nature Communications
  • "Gut microbiota composition during infancy and subsequent behavioural outcomes" (2020) published in EBioMedicine
  • "Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation" (2022) published in Microbiome
  • "Maternal prenatal gut microbiota composition predicts child behaviour" (2021) published in EBioMedicine

Harrison frequently collaborates with other researchers, with several coauthors appearing consistently in their publications. These frequent collaborators include:

  • John M. Wentworth
  • Peter G. Colman
  • Jennifer Couper
  • Peter Vuillermin
  • Megan A. S. Penno

Best Publications

  • Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

    Eliana Mariño;James L Richards;Keiran H McLeod;Dragana Stanley

  • Pro-Inflammatory CD11c+CD206+ Adipose Tissue Macrophages Are Associated With Insulin Resistance in Human Obesity

    John M Wentworth;Gaetano Naselli;Wendy A Brown;Lisa Doyle

  • Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes.

    Margo C. Honeyman;Barbara S. Coulson;Natalie L. Stone;Shane A. Gellert

  • Latent autoimmune diabetes in adults (LADA) should be less latent.

    S Fourlanos;F Dotta;C J Greenbaum;J P Palmer

  • Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice.

    I. L. Campbell;T. W. H. Kay;L. Oxbrow;L. C. Harrison

  • Aerosol Insulin Induces Regulatory CD8 γδ T Cells That Prevent Murine Insulin-dependent Diabetes

    Leonard C. Harrison;Majella Dempsey-Collier;David R. Kramer;Kazuma Takahashi

  • Antigen-induced regulatory T cells in autoimmunity

    Matthias G. von Herrath;Leonard C. Harrison

  • Prediction of MHC class II-binding peptides using an evolutionary algorithm and artificial neural network.

    Vladimir Brusic;George B. Rudy;G. Honeyman;Jürgen Hammer

  • DIURNAL RHYTHMS OF PRO-INFLAMMATORY CYTOKINES: REGULATION BY PLASMA CORTISOL AND THERAPEUTIC IMPLICATIONS

    Nikolai Petrovsky;Peter McNair;Leonard C. Harrison

  • Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele

    Grant Morahan;Dexing Huang;Susie I. Ymer;Michael R. Cancilla

  • Diabetes in transgenic mice resulting from over-expression of class I histocompatibility molecules in pancreatic β cells

    Janette Allison;I. L. Campbell;G. Morahan;T. E. Mandel

  • Transgenic Expression of Mouse Proinsulin II Prevents Diabetes in Nonobese Diabetic Mice

    Michelle B French;Janette Allison;David S Cram;Helen E Thomas

  • Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes

    L.C Harrison;M.C Honeyman;H.J DeAizpurua;R.S Schmidli

  • Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status.

    Diana Mittag;Anna I Proietto;Thomas Loudovaris;Stuart I Mannering

  • T-Cell Epitopes in Type 1 Diabetes Autoantigen Tyrosine Phosphatase IA-2: Potential for Mimicry with Rotavirus and Other Environmental Agents

    Margo C. Honeyman;Natalie L. Stone;Leonard C. Harrison

  • The chronobiology of human cytokine production.

    Nikolai Petrovsky;Leonard C. Harrison

  • IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans.

    I L Campbell;A Iscaro;L C Harrison

  • MHCPEP, a database of MHC-binding peptides: Update 1997

    Vladimir Brusic;George B. Rudy;Leonard C. Harrison

  • Insulin resistance is a risk factor for progression to Type 1 diabetes

    S. Fourlanos;P. Narendran;P. Narendran;G. B. Byrnes;P. G. Colman

  • Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP

    Balasubramanian Krishnamurthy;Nadine L. Dudek;Mark D. McKenzie;Anthony W. Purcell

Frequent Co-Authors

Iain L. Campbell
Iain L. Campbell University of Sydney
Andrew M. Lew
Andrew M. Lew Walter and Eliza Hall Institute of Medical Research
Brian D. Tait
Brian D. Tait Australian Red Cross Lifeblood
Thomas W. H. Kay
Thomas W. H. Kay University of Melbourne
Grant Morahan
Grant Morahan Harry Perkins Institute of Medical Research
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Vladimir Brusic
Vladimir Brusic University of Nottingham Ningbo China
Maria E. Craig
Maria E. Craig University of New South Wales
Nikolai Petrovsky
Nikolai Petrovsky Flinders University
Anthony T. Papenfuss
Anthony T. Papenfuss Walter and Eliza Hall Institute of Medical Research

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