Holger Heine

Overview

Best Publications

• Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

  Egil Lien;Terry K. Means;Holger Heine;Atsutoshi Yoshimura

  943
  Citations

• LPS-induced cytokine production in human monocytes and macrophages.

  Manuela Rossol;Holger Heine;Undine Meusch;Dagmar Quandt

  736
  Citations

• Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

  Silke Walter;Maryse Letiembre;Yang Liu;Holger Heine

  639
  Citations

• Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.

  E. T. Rietschel;H. Brade;O. Holst;L. Brade

  632
  Citations

• TLR2 – promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity

  Ulrich Zähringer;Buko Lindner;Seiichi Inamura;Holger Heine

  453
  Citations

• LPS receptor (CD14): a receptor for phagocytosis of Alzheimer’s amyloid peptide

  Yang Liu;Silke Walter;Massimiliano Stagi;Dmitry Cherny

  452
  Citations

• The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation.

  Antje Blumenthal;Stefan Ehlers;Jörg Lauber;Jan Buer

  437
  Citations

• Molecular mechanisms of endotoxin activity

  Jens Schletter;Holger Heine;Artur J. Ulmer;Ernst T. Rietschel

  429
  Citations

• Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling.

  Katja Farhat;Sabine Riekenberg;Holger Heine;Jennifer Debarry

  391
  Citations

• Lipopolysaccharide and ceramide docking to CD14 provokes ligand‐specific receptor clustering in rafts

  Alexandra Pfeiffer;Alfred Böttcher;Evelyn Orsó;Michael Kapinsky

  385
  Citations

• Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling

  Andra B. Schromm;Egil Lien;Philipp Henneke;Jesse C. Chow

  381
  Citations

• Acinetobacter lwoffii and Lactococcus lactis strains isolated from farm cowsheds possess strong allergy-protective properties

  Jennifer Debarry;Holger Garn;Anna Hanuszkiewicz;Nina Dickgreber

  336
  Citations

• TLR1- and TLR6-independent recognition of bacterial lipopeptides.

  Ute Buwitt-Beckmann;Holger Heine;Karl-Heinz Wiesmüller;Günther Jung

  321
  Citations

• Cutting Edge: Cells That Carry A Null Allele for Toll-Like Receptor 2 Are Capable of Responding to Endotoxin

  Holger Heine;Carsten J. Kirschning;Egil Lien;Brian G. Monks

  311
  Citations

• TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS

  Stefanie Zeuke;Artur J Ulmer;Shoichi Kusumoto;Hugo A Katus

  308
  Citations

• Zinc Signals Are Essential for Lipopolysaccharide-Induced Signal Transduction in Monocytes

  Hajo Haase;Julia L. Ober-Blöbaum;Gabriela Engelhardt;Silke Hebel

  307
  Citations

• Toll-like receptor 6-independent signaling by diacylated lipopeptides.

  Ute Buwitt-Beckmann;Holger Heine;Karl-Heinz Wiesmüller;Günther Jung

  286
  Citations

• Toll-like receptors and their function in innate and adaptive immunity.

  Holger Heine;Egil Lien

  256
  Citations

• Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors.

  Robin R. Ingalls;Holger Heine;Egil Lien;Atsutoshi Yoshimura

  208
  Citations

• Lipopolysaccharide Binding Protein Binds to Triacylated and Diacylated Lipopeptides and Mediates Innate Immune Responses

  Nicolas W. J. Schröder;Holger Heine;Christian Alexander;Maria Manukyan

  206
  Citations