What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Biochemistry, Peptide, Lipopeptide, Major histocompatibility complex and Epitope.
His Biochemistry research includes elements of Stereochemistry and Immune system.
His studies deal with areas such as Amino acid and Binding site as well as Peptide.
Karl-Heinz Wiesmüller interconnects TLR2, Structure–activity relationship and In vivo in the investigation of issues within Lipopeptide.
Much of his study explores Major histocompatibility complex relationship to Cytotoxic T cell.
His Epitope study which covers Virology that intersects with Antibody, CTL* and Priming.
His most cited work include:
- In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine. (623 citations)
- Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling (225 citations)
- TLR1- and TLR6-independent recognition of bacterial lipopeptides. (212 citations)
What are the main themes of his work throughout his whole career to date?
Karl-Heinz Wiesmüller spends much of his time researching Biochemistry, Peptide, Epitope, Lipopeptide and Molecular biology.
His research in Biochemistry intersects with topics in Peptide library and Stereochemistry.
His Peptide study combines topics from a wide range of disciplines, such as Amino acid, Biophysics, MHC class I, Major histocompatibility complex and Binding site.
His Major histocompatibility complex research is classified as research in Immunology.
His biological study spans a wide range of topics, including Cytotoxic T cell, Immune system and Virology.
In his research on the topic of Lipopeptide, Peptide vaccine is strongly related with Adjuvant.
He most often published in these fields:
- Biochemistry (29.21%)
- Peptide (27.53%)
- Epitope (21.91%)
What were the highlights of his more recent work (between 2008-2021)?
- Immunology (16.29%)
- Immune system (14.04%)
- Biochemistry (29.21%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Immunology, Immune system, Biochemistry, Lipopeptide and Antigen.
The study of Immunology is intertwined with the study of Virology in a number of ways.
His work in the fields of Peptide and Elastase overlaps with other areas such as Azurophilic granule and Serpin.
His Peptide research is multidisciplinary, incorporating perspectives in Covalent bond and CD74, Major histocompatibility complex, MHC class II.
Karl-Heinz Wiesmüller has included themes like Amino acid, Adjuvant and Base pair in his Lipopeptide study.
His research in Antigen presentation tackles topics such as CTL* which are related to areas like Epitope.
Between 2008 and 2021, his most popular works were:
- Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein (132 citations)
- Synthesis of novel immunologically active tripalmitoyl-S-glycerylcysteinyl lipopeptides as useful intermediates for immunogen preparations. (87 citations)
- Synthesis of Nα‐Fmoc protected derivatives of S‐(2,3‐dihydroxypropyl)‐cysteine and their application in peptide synthesis (66 citations)
In his most recent research, the most cited papers focused on:
Karl-Heinz Wiesmüller mostly deals with Peptide, Stereochemistry, Immunology, MHC class I and Microbiology.
His work deals with themes such as CD74, Antigen, Major histocompatibility complex and MHC class II, which intersect with Peptide.
He works mostly in the field of Stereochemistry, limiting it down to topics relating to Covalent bond and, in certain cases, Lipopeptide, Immunogen and Hapten.
His Lipopeptide study incorporates themes from Biochemistry and Peptide synthesis.
His study ties his expertise on Virology together with the subject of Immunology.
His research integrates issues of Conformational isomerism, Spin probe and Endoplasmic reticulum in his study of MHC class I.
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