2026 Oliver Smithies: Medicine Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	National Ranking	Publications	Citations
Medicine	110	5516	2974	242	50041

Oliver Smithies publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Oliver Smithies sits on this spectrum.

101 publications 1,796+

This scientist: 242 publications — 7th percentile

7% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Oliver Smithies D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Oliver Smithies sits on this spectrum.

70 D-Index 217+

This scientist: 110 D-Index — 73rd percentile

73% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Research.com Recognitions

2012 - Fellow, National Academy of Inventors
2008 - Distinguished Scientist Award, American Heart Association
2007 - Nobel Prize for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells
2003 - Member of the National Academy of Medicine (NAM)
2001 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
1994 - Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation
1993 - Canada Gairdner International Award
1990 - Canada Gairdner International Award
1986 - Fellow of the American Association for the Advancement of Science (AAAS)
1984 - Karl Landsteiner Memorial Award, American Association of Blood Banks (AABB)
1971 - Member of the National Academy of Sciences

Overview

Oliver Smithies was affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily focused on the field of Medicine, with a significant emphasis on Molecular Biology, Genetics, Cardiology and Cardiovascular Medicine, Physiology, and Endocrinology, Diabetes and Metabolism as subfields.

The scientist's work covered a range of main topics, including:

Coagulation, Bradykinin, Polyphosphates, and Angioedema
Estrogen and related hormone effects
Hormonal Regulation and Hypertension
Inflammatory mediators and NSAID effects
Birth, Development, and Health
Nitric Oxide and Endothelin Effects
Signaling Pathways in Disease

Oliver Smithies contributed to numerous publications, with key recent papers such as:

"Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling" (2021), published in Communications Biology
"The kallikrein-kinin system in diabetic nephropathy" (2020), published by UNC Libraries
"Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia" (2020), published by UNC Libraries
"Abolition of male sexual behaviors in mice lacking estrogen receptors alpha and beta (alpha beta ERKO)" (2021), published by UNC Libraries
"A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy" (2020), published by UNC Libraries

The majority of their publications appeared in UNC Libraries, followed by venues such as Communications Biology, OPAL (Open@LaTrobe) (La Trobe University), and The Journal of Physiological Sciences.

Frequent collaborators included:

Masao Kakoki
Hyungsuk Kim
Nobuyo Maeda
Ruriko Grant
Nobuyuki Takahashi

Oliver Smithies received multiple awards throughout their career, including:

Fellow, National Academy of Inventors (2012)
Distinguished Scientist Award, American Heart Association (2008)
Nobel Prize (2007) for discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells
Member of the National Academy of Medicine (NAM) (2003)
Albert Lasker Award for Basic Medical Research, Lasker Foundation (2001)
Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation (1994)
Canada Gairdner International Award (1993 and 1990)
Fellow of the American Association for the Advancement of Science (AAAS) (1986)
Karl Landsteiner Memorial Award, American Association of Blood Banks (AABB) (1984)
Member of the National Academy of Sciences (1971)

Best Publications

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

Dennis B. Lubahn;Jeffrey S. Moyer;Thomas S. Golding;John F. Couse

2300
Citations
Generation and reproductive phenotypes of mice lacking estrogen receptor β

John H. Krege;Jeffrey B. Hodgin;John F. Couse;Eva Enmark

2147
Citations
An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals

Oliver Smithies

1942
Citations
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

Robert Langenbach;Scott G. Morham;Howard F. Tiano;Charles D. Loftin

1386
Citations
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse

Scott G. Morham;Robert Langenbach;Charles D. Loftin;Howard F. Tiano

1333
Citations
Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells

Beverly H. Koller;Philippa Marrack;John W. Kappler;Oliver Smithies

1277
Citations
An Animal Model for Cystic Fibrosis Made by Gene Targeting

John N. Snouwaert;Kristen K. Brigman;Anne M. Latour;Nadia N. Malouf

1164
Citations
Elevated blood pressures in mice lacking endothelial nitric oxide synthase

Edwardâ€‰G. Shesely;Nobuyo Maeda;H.-S. Kim;Kaushikâ€‰M. Desai

1105
Citations
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.

Radu Daniel Rudic;Edward G. Shesely;Nobuyo Maeda;Oliver Smithies

1057
Citations
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice

Noreen C. Luetteke;Ting Hu Qiu;Robert L. Peiffer;Paula Oliver

955
Citations
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

William A. Kuziel;Sharon J. Morgan;Tracey C. Dawson;Stephanie Griffin

906
Citations
Regulation of blood pressure by the type 1A angiotensin II receptor gene.

Masaki Ito;Michael I. Oliverio;Peter J. Mannon;Christopher F. Best

879
Citations
Mouse Models of Diabetic Nephropathy

Frank C. Brosius;Charles E. Alpers;Erwin P. Bottinger;Matthew D. Breyer

866
Citations
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney.

Steven D. Crowley;Susan B. Gurley;Maria J. Herrera;Phillip Ruiz

802
Citations
Requirement of Mip-1α for an Inflammatory Response to Viral Infection

Donald N. Cook;Melinda A. Beck;Thomas M. Coffman;Suzanne L. Kirby

789
Citations
Male–female differences in fertility and blood pressure in ACE-deficient mice

J. H. Krege;S. W. M. John;L. L. Langenbach;J. B. Hodgin

761
Citations
Genetic control of blood pressure and the angiotensinogen locus.

Hyung S Kim;John H. Krege;Kimberly D. Kluckman;John R. Hagaman

760
Citations
Homologous recombination for universal donor cells and chimeric mammalian hosts

Raju S. Kucherlapati;Beverly H. Koller;Oliver Smithies

748
Citations
Genetic decreases in atrial natriuretic peptide and salt-sensitive hypertension

Simon W. M. John;John H. Krege;Paula M. Oliver;John R. Hagaman

746
Citations
Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

Paula M. Oliver;Jennifer E. Fox;Ron Kim;Howard A. Rockman

703
Citations

Frequent Co-Authors

Nobuyo Maeda University of North Carolina at Chapel Hill

Thomas M. Coffman Duke University

Beverly H. Koller University of North Carolina at Chapel Hill

J. Charles Jennette University of North Carolina at Chapel Hill

Robert Langenbach National Institutes of Health

Howard A. Rockman Duke University

Kenneth S. Korach National Institutes of Health

Donald N. Cook National Institutes of Health

Simon W. M. John Columbia University

Raju Kucherlapati Harvard University

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