D-Index & Metrics Best Publications
David S. Rosenblatt

David S. Rosenblatt

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 9,528 181 World Ranking 10570 National Ranking 363

Research.com Recognitions

Awards & Achievements

1966 - Fellow of the American Statistical Association (ASA)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Mutation

His main research concerns Genetics, Internal medicine, Endocrinology, Methionine synthase and Homocystinuria. Genetics is closely attributed to Molecular biology in his research. David S. Rosenblatt interconnects Teratology and Gestation in the investigation of issues within Internal medicine.

The study incorporates disciplines such as Pregnancy and Cobalamin metabolism in addition to Endocrinology. His Methionine synthase study is focused on Methionine and Biochemistry. The Methionine study combines topics in areas such as Cobalamin and Homocysteine.

His most cited work include:

  • Human Methionine Synthase: cDNA Cloning and Identification of Mutations in Patients of the cblG Complementation Group of Folate/Cobalamin Disorders (349 citations)
  • Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria (316 citations)
  • Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects. (270 citations)

What are the main themes of his work throughout his whole career to date?

David S. Rosenblatt focuses on Internal medicine, Genetics, Endocrinology, Biochemistry and Cobalamin. Internal medicine is closely attributed to Gastroenterology in his work. His work deals with themes such as Molecular biology and Methylmalonic aciduria, which intersect with Genetics.

His Molecular biology research focuses on subjects like Complementation, which are linked to Methylmalonyl-CoA mutase. His research integrates issues of Homocystinuria, Prenatal diagnosis and Methylenetetrahydrofolate reductase in his study of Endocrinology. His studies deal with areas such as Genetic heterogeneity and Severe combined immunodeficiency as well as Cobalamin.

He most often published in these fields:

  • Internal medicine (40.80%)
  • Genetics (39.80%)
  • Endocrinology (35.82%)

What were the highlights of his more recent work (between 2014-2021)?

  • Genetics (39.80%)
  • Cobalamin (30.85%)
  • Gene (18.41%)

In recent papers he was focusing on the following fields of study:

David S. Rosenblatt mainly investigates Genetics, Cobalamin, Gene, Methylmalonic aciduria and Internal medicine. His work on DNA sequencing, Mutation, Missense mutation and Zebrafish as part of general Genetics research is frequently linked to Identification, bridging the gap between disciplines. The study incorporates disciplines such as Sanger sequencing, Methionine synthase and Severe combined immunodeficiency in addition to Cobalamin.

His Gene research includes themes of Genetic testing and Bioinformatics. He combines subjects such as GTPase, Genome, Chaperone, Mutase and G protein with his study of Methylmalonic aciduria. David S. Rosenblatt focuses mostly in the field of Internal medicine, narrowing it down to matters related to Endocrinology and, in some cases, Transient receptor potential channel.

Between 2014 and 2021, his most popular works were:

  • Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis (37 citations)
  • Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis (37 citations)
  • Characterization and Review of MTHFD1 Deficiency: Four New Patients, Cellular Delineation and Response to Folic and Folinic Acid Treatment (23 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Mutation

David S. Rosenblatt mostly deals with Gene, Genetics, Mutation, Cobalamin and Biochemistry. The concepts of his Genetics study are interwoven with issues in Vitamin B12, Methylmalonic acid and Medical diagnosis. His Mutation research incorporates elements of Internal medicine, Genetic testing, Endocrinology and DNA sequencing.

His work in the fields of Procollagen peptidase overlaps with other areas such as SEC23A. His Cobalamin study frequently involves adjacent topics like Methionine synthase. Much of his study explores Biochemistry relationship to Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders.

D. Leclerc;E. Campeau;P. Goyette;C. E. Adjalla.
Human Molecular Genetics (1996)

545 Citations

Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria

D. Leclerc;A. Wilson;R. Dumas;C. Gafuik.
Proceedings of the National Academy of Sciences of the United States of America (1998)

523 Citations

Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency.

P Goyette;P Frosst;D S Rosenblatt;R Rozen.
American Journal of Human Genetics (1995)

400 Citations

Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects.

Benedicte Christensen;Laura Arbour;Pamela Tran;Daniel Leclerc.
American Journal of Medical Genetics (1999)

397 Citations

Correlation of a Common Mutation in the Methylenetetrahydrofolate Reductase Gene With Plasma Homocysteine in Patients With Premature Coronary Artery Disease

Benedicte Christensen;Phyllis Frosst;Suzanne Lussier-Cacan;Jacob Selhub.
Arteriosclerosis, Thrombosis, and Vascular Biology (1997)

317 Citations

Novel Reductant for Determination of Total Plasma Homocysteine

Brian M. Gilfix;David W. Blank;David S. Rosenblatt.
Clinical Chemistry (1997)

223 Citations

Adverse Effect of Nitrous Oxide in a Child with 5,10-Methylenetetrahydrofolate Reductase Deficiency

Rebecca R Selzer;David S Rosenblatt;Renata Laxova;Kirk Hogan.
The New England Journal of Medicine (2003)

213 Citations

The effect of 677C-->T and 1298A-->C mutations on plasma homocysteine and 5,10-methylenetetrahydrofolate reductase activity in healthy subjects.

A. Chango;F. Boisson;F. Barbé;D. Quilliot.
British Journal of Nutrition (2000)

213 Citations

Functional methionine synthase deficiency (cblE and cblG): clinical and biochemical heterogeneity.

D Watkins;D S Rosenblatt.
American Journal of Medical Genetics (1989)

206 Citations

Severe and mild mutations in cis for the methylenetetrahydrofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR.

Goyette P;Christensen B;Rosenblatt Ds;Rozen R.
American Journal of Human Genetics (1996)

199 Citations

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