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D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
9825
World Ranking
19068
National Ranking
7783

Overview

Donald W. Jacobsen is affiliated with the Cleveland Clinic Lerner College of Medicine in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in related subfields such as Rheumatology, Molecular Biology, Clinical Biochemistry, Hematology, and Nutrition and Dietetics.

The scientist's recent scholarly output features papers that focus largely on vitamin B12 metabolism, genetic and metabolic disorders, and related biochemical pathways. Key publications include:

  • Vitamin B12 Status and Supplementation in Plant-Based Diets, 2024, Food and Nutrition Bulletin
  • Versatile enzymology and heterogeneous phenotypes in cobalamin complementation type C disease, 2022, iScience
  • Intracellular processing of vitamin B12 by MMACHC (CblC), 2022, Vitamins and hormones
  • Thiolatocobalamins repair the activity of pathogenic variants of the human cobalamin processing enzyme CblC, 2020, Biochimie
  • Elevated Plasma Vitamin B12 in Patients with Hepatic Glycogen Storage Diseases, 2020, Journal of Clinical Medicine

These publications highlight a focus on Folate and B Vitamins Research, Porphyrin Metabolism and Disorders, Metabolism and Genetic Disorders, Iron Metabolism and Disorders, Vitamin C and Antioxidants Research, Diet and metabolism studies, and Glycogen Storage Diseases and Myoclonus.

Frequent collaborators contribute to a multidisciplinary approach to their research, including:

  • Luciana Hannibal
  • Ute Spiekerkoetter
  • Anna J. Esser
  • Katharina Klotz
  • Srijan Mukherjee

Donald W. Jacobsen's work is published in notable venues such as iScience, Vitamins and hormones, Food and Nutrition Bulletin, Biochimie, and the Journal of Clinical Medicine.

Best Publications

  • Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis

    R. Clarke;R. Collins;S. Lewington;A. Donald

  • Homocysteine and coronary atherosclerosis

    Ellen L. Mayer;Donald W. Jacobsen;Killian Robinson

  • Homocysteine in health and disease

    Ralph Carmel;Donald W. Jacobsen

  • Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: sex differences and correlation with cobalamin and folate concentrations in healthy subjects.

    Donald W. Jacobsen;Vytenis J. Gatautis;Ralph Green;Killian Robinson

  • Homocysteine and vitamins in cardiovascular disease

    Donald W. Jacobsen

  • Prospective Study of Hyperhomocysteinemia as an Adverse Cardiovascular Risk Factor in End-Stage Renal Disease

    Ali Moustapha;Arabi Naso;Maher Nahlawi;Anjan Gupta

  • Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease.

    Killian Robinson;Ellen L. Mayer;Dave P. Miller;Ralph Green

  • Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: implications for vascular disease.

    Ranjana Poddar;Natarajan Sivasubramanian;Patricia M. DiBello;Killian Robinson

  • Hyperhomocysteinemia Confers an Independent Increased Risk of Atherosclerosis in End-Stage Renal Disease and Is Closely Linked to Plasma Folate and Pyridoxine Concentrations

    Killian Robinson;Anjan Gupta;Vincent Dennis;Kristopher Arheart

  • Homocysteine and Its Disulfide Derivatives: A Suggested Consensus Terminology

    S. Harvey Mudd;James D. Finkelstein;Helga Refsum;Per M. Ueland

  • Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency

    Luciana Hannibal;Vegard Lysne;Anne-Lise Bjørke-Monsen;Sidney Behringer

  • TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia

    Gazi S. Hossain;Johannes V. van Thienen;Geoff H. Werstuck;Ji Zhou

  • Homocysteine metabolism in cardiovascular cells and tissues: implications for hyperhomocysteinemia and cardiovascular disease.

    P. Chen;R. Poddar;E. V. Tipa;P. M. Dibello

  • Hyperhomocysteinemia and Oxidative Stress Time for a Reality Check

    Donald W. Jacobsen

  • Biomarkers of vitamin B-12 status in NHANES: a roundtable summary

    Elizabeth A Yetley;Christine M Pfeiffer;Karen W Phinney;Regan L Bailey

  • Serum cobalamin, homocysteine, and methylmalonic acid concentrations in a multiethnic elderly population: ethnic and sex differences in cobalamin and metabolite abnormalities

    Ralph Carmel;Ralph Green;Donald W Jacobsen;Karsten Rasmussen

  • Albumin thiolate anion is an intermediate in the formation of albumin-S-S-homocysteine

    Shantanu Sengupta;Hong Chen;Tadayasu Togawa;Patricia M. DiBello

  • Protein and lipid oxidation of banked human erythrocytes: role of glutathione.

    Umakant J Dumaswala;Limei Zhuo;Donald W Jacobsen;Sushil K Jain

  • Relative roles of albumin and ceruloplasmin in the formation of homocystine, homocysteine-cysteine-mixed disulfide, and cystine in circulation.

    Shantanu Sengupta;Charles Wehbe;Alana K. Majors;Michael E. Ketterer

  • Processing of alkylcobalamins in mammalian cells: A role for the MMACHC (cblC) gene product

    Luciana Hannibal;Jihoe Kim;Nicola E. Brasch;Sihe Wang

Frequent Co-Authors

Laura E. Nagy
Laura E. Nagy Cleveland Clinic
Richard C. Austin
Richard C. Austin McMaster University
Steven E. Nissen
Steven E. Nissen Cleveland Clinic
Jacob Selhub
Jacob Selhub Tufts University
Sally P. Stabler
Sally P. Stabler University of Colorado Anschutz Medical Campus
Henk J. Blom
Henk J. Blom Erasmus MC
Paul F. Jacques
Paul F. Jacques Tufts University
Ruma Banerjee
Ruma Banerjee University of Michigan–Ann Arbor
Belinda Willard
Belinda Willard Cleveland Clinic
Barry Shane
Barry Shane University of California, Berkeley

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