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D-Index & Metrics

Microbiology

D-Index
50
Citations
8174
World Ranking
4481
National Ranking
1730

Overview

Joaquín Madrenas is affiliated with the University of California, Los Angeles in the United States. Their research spans multiple disciplines, primarily focusing on medicine as well as biochemistry, genetics, and molecular biology. They have contributed to several specific subfields, including molecular biology, oncology, otorhinolaryngology, food science, and surgery.

Their work covers a range of main topics, such as:

  • DNA repair mechanisms
  • Sinusitis and nasal conditions
  • Probiotics and fermented foods
  • Nasal surgery and airway studies
  • Carcinogens and genotoxicity assessment
  • Cancer-related molecular pathways
  • Melanoma and MAPK pathways

Joaquín Madrenas has authored research published in various scientific venues, including:

  • Frontiers in Cellular and Infection Microbiology
  • eLife
  • Science Signaling
  • Biomolecules
  • bioRxiv (Cold Spring Harbor Laboratory)

Selected recent papers include:

  • "Intranasal Application of Lactococcus lactis W136 Is Safe in Chronic Rhinosinusitis Patients With Previous Sinus Surgery" (2020), published in Frontiers in Cellular and Infection Microbiology
  • "A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation" (2021), published in eLife
  • "The induction of SHP-1 degradation by TAOK3 ensures the responsiveness of T cells to TCR stimulation" (2024), published in Science Signaling
  • "NOD2 Agonism Counter-Regulates Human Type 2 T Cell Functions in Peripheral Blood Mononuclear Cell Cultures: Implications for Atopic Dermatitis" (2023), published in Biomolecules
  • "A novel, ataxic mouse model of Ataxia Telangiectasia caused by a clinically relevant nonsense mutation" (2020), published in bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Joaquín Madrenas include:

  • H. Daniel Perez
  • May F. Abdallah
  • Jose I Chavira
  • Angelina S Norris
  • Martin Egeland

Best Publications

  • Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

    Joaquín Madrenas;Ronald L. Wange;Jennifer L. Wang;Noah Isakov

  • A MOLECULAR PERSPECTIVE OF CTLA-4 FUNCTION

    Wendy A Teft;Mark G Kirchhof;Joaquín Madrenas

  • Human Embryonic Stem Cells Possess Immune-Privileged Properties

    Li Li;Miren L. Baroja;Anish Majumdar;Kristin Chadwick;Kristin Chadwick

  • CTLA-4 (CD152) Can Inhibit T Cell Activation by Two Different Mechanisms Depending on Its Level of Cell Surface Expression

    Beatriz M. Carreno;Frann Bennett;Thu A. Chau;Vincent Ling

  • Age-Specific Mortality During the 1918 Influenza Pandemic: Unravelling the Mystery of High Young Adult Mortality

    Alain Gagnon;Matthew S Miller;Stacey A Hallman;Robert Bourbeau

  • Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool.

    J. García-Castro;C. Trigueros;Joaquin Madrenas;J. A. Pérez-Simón

  • The Efficiency of CD4 Recruitment to Ligand-engaged TCR Controls the Agonist/Partial Agonist Properties of Peptide–MHC Molecule Ligands

    Joaquín Madrenas;Luan A. Chau;Judy Smith;Jeffrey A. Bluestone

  • The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i‐AAA protease YME1L

    Timothy Wai;Shotaro Saita;Hendrik Nolte;Sebastian Müller

  • Oral Administration of the Probiotic Combination Lactobacillus Rhamnosus GR-1 and L. Fermentum RC-14 for Human Intestinal Applications

    Gillian E. Gardiner;Christine Heinemann;Miren L. Baroja;Andrew W. Bruce

  • Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome

    Thu A Chau;Michelle L McCully;Michelle L McCully;William Brintnell;Gary An

  • Stomatin-Like Protein 2 Binds Cardiolipin and Regulates Mitochondrial Biogenesis and Function

    Darah A. Christie;Caitlin D. Lemke;Isaac M. Elias;Luan A. Chau

  • Metalloproteinases are involved in lipopolysaccharide- and tumor necrosis factor-alpha-mediated regulation of CXCR1 and CXCR2 chemokine receptor expression.

    Masud H. Khandaker;Gordon Mitchell;Gordon Mitchell;Luoling Xu;Luoling Xu;Joseph D. Andrews;Joseph D. Andrews

  • Bacterial Superantigens Bypass Lck-Dependent T Cell Receptor Signaling by Activating a Gα11-Dependent, PLC-β-Mediated Pathway

    Clara Bueno;Clara Bueno;Caitlin D. Lemke;Caitlin D. Lemke;Gabriel Criado;Gabriel Criado;Miren L. Baroja;Miren L. Baroja

  • Surface Cytotoxic T Lymphocyte–associated Antigen 4 Partitions Within Lipid Rafts and Relocates to the Immunological Synapse under Conditions of Inhibition of T Cell Activation

    Peter J. Darlington;Miren L. Baroja;Thu A. Chau;Eric Siu

  • A modulatory interleukin-10 response to staphylococcal peptidoglycan prevents Th1/Th17 adaptive immunity to Staphylococcus aureus.

    Vanessa Frodermann;Thu A. Chau;Samar Sayedyahossein;Judit M. Toth

  • Inhibition of CTLA-4 function by the regulatory subunit of serine/threonine phosphatase 2A

    Miren L. Baroja;Lalitha Vijayakrishnan;Estelle Bettelli;Peter J. Darlington

  • Variant TCR ligands: new insights into the molecular basis of antigen-dependent signal transduction and T-cell activation

    Joaquı́n Madrenas;Ronald N. Germain

  • Interleukin 2 production, not the pattern of early T-cell antigen receptor-dependent tyrosine phosphorylation, controls anergy induction by both agonists and partial agonists

    Joaquin Madrenas;Ronald H. Schwartz;Ronald N. Germain

  • Tumor Suppression by Phospholipase C-β3 via SHP-1-Mediated Dephosphorylation of Stat5

    Wenbin Xiao;Hong Hong;Yuko Kawakami;Yuko Kato

  • Dissociation of Intracellular Signaling Pathways in Response to Partial Agonist Ligands of the T Cell Receptor

    Luan A. Chau;Jeffrey A. Bluestone;Joaquín Madrenas

  • The molecular immunology of acute rejection: an overview.

    Philip F. Halloran;Anthony P. Broski;Thomas D. Batiuk;Joaquin Madrenas

Frequent Co-Authors

John K. McCormick
John K. McCormick University of Western Ontario
Philip F. Halloran
Philip F. Halloran University of Alberta
Bhagirath Singh
Bhagirath Singh University of Western Ontario
David J. Kelvin
David J. Kelvin Dalhousie University
Mickie Bhatia
Mickie Bhatia McMaster University
David E. Heinrichs
David E. Heinrichs University of Western Ontario
Robert Zhong
Robert Zhong University of Western Ontario
Grant M. Hatch
Grant M. Hatch University of Manitoba
Stephen S. G. Ferguson
Stephen S. G. Ferguson University of Ottawa
Michael L. Dustin
Michael L. Dustin University of Oxford

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