World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
85
Citations
25550
World Ranking
1321
National Ranking
683

Overview

Kim Bottomly is affiliated with Yale University in the United States and conducts research primarily in the fields of Medicine and Pharmacology, Toxicology and Pharmaceutics. Their work spans several subfields including Immunology and Allergy, Pharmaceutical Science, and Radiology, Nuclear Medicine and Imaging.

The main topics in Bottomly's research include Food Allergy and Anaphylaxis Research, Advanced Drug Delivery Systems, and Monoclonal and Polyclonal Antibodies Research.

Bottomly has published research in the journal Communications Materials. One of their recent papers is titled "Scaleable production of highly loaded protein nanoparticles for immune modulation," published in 2024 in Communications Materials.

  • Michael J. Caplan
  • Richard Baldwin
  • Xiangyun Yin
  • Alexander Grishin
  • Stephanie C. Eisenbarth

Frequent co-authors in Bottomly's publications include Michael J. Caplan, Richard Baldwin, Xiangyun Yin, Alexander Grishin, and Stephanie C. Eisenbarth.

Best Publications

  • INDUCTION OF TH1 AND TH2 CD4+ T CELL RESPONSES : THE ALTERNATIVE APPROACHES

    Stephanie L. Constant;Kim Bottomly

  • Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled Antigen

    Stephanie C. Eisenbarth;Damani A. Piggott;James W. Huleatt;Irene Visintin

  • Signals and signs for lymphocyte responses

    Charles A. Janeway;Kim Bottomly

  • Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells.

    Stephanie Constant;Christiane Pfeiffer;Ann Woodard;Theresa Pasqualini

  • Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene.

    Dong-Hong Zhang;Lauren Cohn;Prabir Ray;Kim Bottomly

  • Induction of Airway Mucus Production By T Helper 2 (Th2) Cells: A Critical Role For Interleukin 4 In Cell Recruitment But Not Mucus Production

    Lauren Cohn;Robert J. Homer;Anthony Marinov;John Rankin

  • Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo.

    C Pfeiffer;J Stein;S Southwood;H Ketelaar

  • A functional dichotomy in CD4+ T lymphocytes

    Kim Bottomly

  • To respond or not to respond: T cells in allergic asthma

    Christina A Herrick;Kim Bottomly

  • IL-4-INDEPENDENT INDUCTION OF AIRWAY HYPERRESPONSIVENESS BY TH2, BUT NOT TH1, CELLS

    Lauren Cohn;Jeffrey S. Tepper;Kim Bottomly

  • B lymphocytes can be competent antigen-presenting cells for priming CD4+ T cells to protein antigens in vivo.

    S Constant;N Schweitzer;J West;P Ranney

  • Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiation.

    X Tao;S Constant;P Jorritsma;K Bottomly

  • T Helper 1 Cells and Interferon γ Regulate Allergic Airway Inflammation and Mucus Production

    Lauren Cohn;Robert J. Homer;Naiqian Niu;Kim Bottomly

  • Quantitative variation in la antigen expression plays a central role in immune regulation.

    Charles A Janeway;Kim Bottomly;John Babich;Patricia Conrad

  • Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice.

    D N Ernst;M V Hobbs;B E Torbett;A L Glasebrook

  • CD4+ T Cells: Specificity and Function

    Charles A. Janeway;Simon Carding;Barry Jones;Joseph Murray

  • The relationship of IL-4- and IFNγ-producing T cells studied by lineage ablation of IL-4-producing cells

    Yumiko Kamogawa;Lori-ann E. Minasi;Simon R. Carding;Kim Bottomly;Kim Bottomly

  • Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils.

    Lauren Cohn;Robert J. Homer;Heather MacLeod;Markus Mohrs

  • A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines.

    Kim Bottomly;Mohammad Luqman;Laurence Greenbaum;Simon Carding

  • Late dominance of the inflammatory process in murine influenza by gamma/delta + T cells.

    S R Carding;W Allan;S Kyes;A Hayday

Frequent Co-Authors

Simon R. Carding
Simon R. Carding University of East Anglia
Charles A. Janeway
Charles A. Janeway Yale University
Richard A. Flavell
Richard A. Flavell Yale University
Donna L. Farber
Donna L. Farber Columbia University
Adrian Hayday
Adrian Hayday King's College London
Robert J. Homer
Robert J. Homer Yale University
Hugh A. Sampson
Hugh A. Sampson Icahn School of Medicine at Mount Sinai
Peter C. Doherty
Peter C. Doherty University of Melbourne
Joseph A. Madri
Joseph A. Madri Yale University

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