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Sebastian Wesselborg

Sebastian Wesselborg

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
20329
World Ranking
7684
National Ranking
559

Overview

Sebastian Wesselborg is affiliated with the University of Tübingen in Germany. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with additional contributions to medicine. Within these domains, Wesselborg has concentrated on molecular biology, pharmacology, organic chemistry, genetics, and materials chemistry.

The main topics covered in Wesselborg's work include:

  • Microbial Natural Products and Biosynthesis
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • Marine Sponges and Natural Products
  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research

Wesselborg has published papers in several venues, with frequent publications in:

  • Cell Death and Disease
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecules
  • Cell Death Discovery
  • The Cambridge Structural Database

Notable recent papers by Wesselborg include:

  • Fin56-induced ferroptosis is supported by autophagy-mediated GPX4 degradation and functions synergistically with mTOR inhibition to kill bladder cancer cells, 2021, Cell Death and Disease
  • 40 Years of Research on Polybrominated Diphenyl Ethers (PBDEs)-A Historical Overview and Newest Data of a Promising Anticancer Drug, 2021, Molecules
  • Sesterterpenes and macrolide derivatives from the endophytic fungus Aplosporella javeedii, 2020, Fitoterapia
  • Induction of New Lactam Derivatives From the Endophytic Fungus Aplosporella javeedii Through an OSMAC Approach, 2020, Frontiers in Microbiology
  • An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis, 2021, Nucleic Acids Research

The scientist has collaborated frequently with several co-authors, including:

  • Björn Stork
  • Laura Schmitt
  • Fabian Stuhldreier
  • Christoph Peter
  • Kai Stühler

Best Publications

  • Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks.

    Sebastian Alers;Antje S. Löffler;Sebastian Wesselborg;Björn Stork

  • Apoptosis signaling by death receptors

    Klaus Schulze-Osthoff;Davide Ferrari;Marek Los;Sebastian Wesselborg

  • Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal

    Kirsten Lauber;Erwin Bohn;Stefan Martin Kröber;Yi Jin Xiao

  • A Caspase-Related Protease Regulates Apoptosis in Yeast.

    Frank Madeo;Eva Herker;Corinna Maldener;Silke Wissing

  • Clearance of Apoptotic Cells: Getting Rid of the Corpses

    Kirsten Lauber;Sibylle G. Blumenthal;Michaela Waibel;Sebastian Wesselborg

  • The Role of Caspases in Development, Immunity, and Apoptotic Signal Transduction: Lessons from Knockout Mice

    Marek Los;Sebastian Wesselborg;Klaus Schulze-Osthoff

  • Human mature red blood cells express caspase-3 and caspase-8, but are devoid of mitochondrial regulators of apoptosis

    C P Berg;I H Engels;A Rothbart;K Lauber

  • Cancer stem cell markers in common cancers – therapeutic implications

    Thomas Klonisch;Emilia Wiechec;Sabine Hombach-Klonisch;Sudharsana R. Ande

  • Regulation of NF-κB Activation by MAP Kinase Cascades

    Klaus Schulze-Osthoff;Davide Ferrari;Kristina Riehemann;Sebastian Wesselborg

  • Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.

    Sebastian Wesselborg;Ingo H. Engels;Evi Rossmann;Marek Los

  • Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65.

    Davide Ferrari;Sebastian Wesselborg;Manuel K.A. Bauer;Klaus Schulze-Osthoff

  • S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway

    Saeid Ghavami;Iran Rashedi;Brian M. Dattilo;Mehdi Eshraghi

  • P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death.

    Davide Ferrari;Marek Los;Manuel K.A. Bauer;Peter Vandenabeele

  • Activation of Transcription Factor NF-κB and p38 Mitogen-activated Protein Kinase Is Mediated by Distinct and Separate Stress Effector Pathways *

    S. Wesselborg;M. K. A. Bauer;M. Vogt;M. L. Schmitz

  • Oxidative stress and signal transduction.

    K. Schulze-Osthoff;M. K. A. Bauer;M. Vogt;S. Wesselborg

  • Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis.

    Ingo H Engels;Ania Stepczynska;Christopher Stroh;Kirsten Lauber

  • Differential Regulation and ATP Requirement for Caspase-8 and Caspase-3 Activation during CD95- and Anticancer Drug–induced Apoptosis

    Davide Ferrari;Ania Stepczynska;Marek Los;Sebastian Wesselborg

  • Mistletoe Lectin Activates Caspase-8/FLICE Independently of Death Receptor Signaling and Enhances Anticancer Drug-induced Apoptosis

    Heike Bantel;Ingo H. Engels;Wolfgang Voelter;Klaus Schulze-Osthoff

  • Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A.

    Christoph Peter;Michaela Waibel;Caius G. Radu;Li V. Yang

  • Role of Reactive Oxygen Intermediates in Activation-induced CD95 (APO-1/Fas) Ligand Expression

    Manuel K. A. Bauer;Markus Vogt;Marek Los;Johanna Siegel

Frequent Co-Authors

Kirsten Lauber
Kirsten Lauber Ludwig-Maximilians-Universität München
Klaus Schulze-Osthoff
Klaus Schulze-Osthoff University of Tübingen
Peter Proksch
Peter Proksch Heinrich Heine University Düsseldorf
Marek Los
Marek Los Silesian University of Technology
Claus Belka
Claus Belka Ludwig-Maximilians-Universität München
Peter Brossart
Peter Brossart University Hospital Bonn
Martin Schaller
Martin Schaller University of Tübingen
Alessio Nencioni
Alessio Nencioni University of Genoa
Davide Ferrari
Davide Ferrari University of Ferrara
Ingo B. Autenrieth
Ingo B. Autenrieth Heidelberg University

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