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Cevayir Coban

Cevayir Coban

D-Index & Metrics

Microbiology

D-Index
48
Citations
16261
World Ranking
4624
National Ranking
188

Overview

Cevayir Coban is affiliated with the University of Tokyo in Japan and conducts research primarily in the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Immunology, Molecular Biology, Public Health, Environmental and Occupational Health, Infectious Diseases, and Oncology.

The scientist's research covers a variety of topics with a focus on immune responses, infectious diseases, and molecular mechanisms. Key topics include interferon and immune responses, malaria research and control, inflammasome and immune disorders, viral infections and vectors, mosquito-borne diseases and control, CRISPR and genetic engineering, and virus-based gene therapy research.

Recent papers authored or coauthored by Cevayir Coban and notable collaborators demonstrate a focus on immunological mechanisms and infectious diseases. These include:

  • The host targeting effect of chloroquine in malaria (2020), published in Current Opinion in Immunology
  • TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation (2021), published in Proceedings of the National Academy of Sciences
  • Anti-tumor immunity by transcriptional synergy between TLR9 and STING activation (2022), published in International Immunology
  • B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice (2021), published in The Journal of Experimental Medicine
  • 5,6-dimethylxanthenone-4-acetic acid (DMXAA), a partial STING agonist, competes for human STING activation (2024), published in Frontiers in Immunology

Cevayir Coban frequently collaborates with researchers such as Ken J. Ishii, Michelle Sue Jann Lee, Kouji Kobiyama, Burcu Temizoz, and Tomoya Hayashi, reflecting a network of scientific partnerships primarily in immunology and related biomedical fields.

Publication venues where their work appears regularly include:

  • International Immunology
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current Opinion in Immunology
  • Proceedings of the National Academy of Sciences

Best Publications

  • IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

    Taro Kawai;Ken Takahashi;Ken Takahashi;Shintaro Sato;Cevayir Coban

  • Interferon-|[alpha]| induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

    Taro Kawai;Shintaro Sato;Ken J. Ishii;Cevayir Coban

  • A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA

    Ken J Ishii;Cevayir Coban;Hiroki Kato;Ken Takahashi

  • Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

    Cevayir Coban;Ken J. Ishii;Taro Kawai;Hiroaki Hemmi

  • TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

    Ken J. Ishii;Tatsukata Kawagoe;Shohei Koyama;Kosuke Matsui

  • Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections

    Ken J. Ishii;Shohei Koyama;Atsushi Nakagawa;Cevayir Coban

  • Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction

    Satoshi Uematsu;Shintaro Sato;Masahiro Yamamoto;Tomonori Hirotani

  • Essential role of IPS-1 in innate immune responses against RNA viruses

    Himanshu Kumar;Taro Kawai;Hiroki Kato;Shintaro Sato

  • DNA released from dying host cells mediates aluminum adjuvant activity

    Thomas Marichal;Keiichi Ohata;Denis Bedoret;Claire Mesnil

  • Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells.

    Satoshi Uematsu;Myoung Ho Jang;Nicolas Chevrier;Zijin Guo

  • Innate immune response to viral infection.

    Shohei Koyama;Ken J. Ishii;Cevayir Coban;Shizuo Akira

  • Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination.

    Shohei Koyama;Ken J. Ishii;Himanshu Kumar;Takeshi Tanimoto

  • Genomic DNA Released by Dying Cells Induces the Maturation of APCs

    Ken J. Ishii;Koichi Suzuki;Cevayir Coban;Fumihiko Takeshita

  • Repeated administration of synthetic oligodeoxynucleotides expressing CpG motifs provides long-term protection against bacterial infection

    Dennis M. Klinman;Jackie Conover;Cevahir Coban

  • Silica Crystals and Aluminum Salts Regulate the Production of Prostaglandin in Macrophages via NALP3 Inflammasome-Independent Mechanisms

    Etsushi Kuroda;Ken J. Ishii;Satoshi Uematsu;Keiichi Ohata

  • Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR9

    Cevayir Coban;Yoshikatsu Igari;Masanori Yagi;Thornik Reimer

  • Pathological role of Toll-like receptor signaling in cerebral malaria

    Cevayir Coban;Ken J. Ishii;Satoshi Uematsu;Nobuko Arisue

  • A distinct subpopulation of CD25− T-follicular regulatory cells localizes in the germinal centers

    James Badger Wing;Yohko Kitagawa;Michela Locci;Hannah Hume

  • Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes.

    Shohei Koyama;Shohei Koyama;Taiki Aoshi;Takeshi Tanimoto;Yutaro Kumagai

  • Novel strategies to improve DNA vaccine immunogenicity.

    Cevayir Coban;Kouji Kobiyama;Taiki Aoshi;Fumihiko Takeshita

  • Manifold mechanisms of Toll-like receptor-ligand recognition.

    Ken J. Ishii;Cevayir Coban;Shizuo Akira

Frequent Co-Authors

Ken J. Ishii
Ken J. Ishii University of Tokyo
Shizuo Akira
Shizuo Akira Osaka University
Toshihiro Horii
Toshihiro Horii Osaka University
Satoshi Uematsu
Satoshi Uematsu Osaka Metropolitan University
Taro Kawai
Taro Kawai Nara Institute of Science and Technology
Osamu Takeuchi
Osamu Takeuchi Kyoto University
Masahiro Yamamoto
Masahiro Yamamoto Osaka University
Nirbhay Kumar
Nirbhay Kumar George Washington University
Dennis M. Klinman
Dennis M. Klinman National Institutes of Health
Kazuo Sakurai
Kazuo Sakurai The University of Kitakyushu

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