World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
86
Citations
27890
World Ranking
1290
National Ranking
653

Biology and Biochemistry

D-Index
85
Citations
27665
World Ranking
3133
National Ranking
1584

Overview

David K. Grandy is affiliated with Oregon Health & Science University in the United States. Their research spans several interconnected fields including biochemistry, genetics, molecular biology, and medicine. Within these broader areas, Grandy's work focuses on molecular biology, infectious diseases, radiology, nuclear medicine, immunology, and cellular and molecular neuroscience.

Grandy has contributed to research on receptor mechanisms and signaling, SARS-CoV-2 and COVID-19, monoclonal and polyclonal antibodies, the complement system in diseases, neurotransmitter receptor influence on behavior, pharmacological receptor mechanisms and effects, and pancreatic function related to diabetes.

Recent publications include:

  • Hexamerization of Anti-SARS CoV IgG1 Antibodies Improves Neutralization Capacity, 2022, Frontiers in Immunology
  • Dopamine receptors in GtoPdb v.2023.1, 2023, IUPHAR/BPS Guide to Pharmacology CITE
  • Issue Information, 2022, Synapse
  • Trace Amines are Essential Metabolites for the Autocrine Regulation of β-Cell Signaling and Insulin Secretion, 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • Dopamine receptors in GtoPdb v.2025.3, 2025, IUPHAR/BPS Guide to Pharmacology CITE

Frequent co-authors collaborating with Grandy include:

  • Jean-Martin Beaulieu
  • Emiliana Borrelli
  • Arvid Carlsson
  • Marc G. Caron
  • Olivier Civelli

Grandy's work is regularly published in venues such as:

  • IUPHAR/BPS Guide to Pharmacology CITE
  • Frontiers in Immunology
  • Synapse
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

    Rainer K. Reinscheid;Hans Peter Nothacker;Anne Bourson;Ali Ardati

  • Cloning and expression of a rat D2 dopamine receptor cDNA.

    James R. Bunzow;Hubert H. M. Van Tol;David K. Grandy;Paul Albert

  • Molecular Diversity of the Dopamine Receptors

    Olivier Civelli;James R. Bunzow;David K. Grandy

  • Cloning and expression of human and rat D1 dopamine receptors

    Qun Yong Zhou;David K. Grandy;Lisa Thambi;Jake A. Kushner

  • Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type

    James R. Bunzow;Carmen Saez;Marty Mortrud;Claudia Bouvier

  • Amphetamine, 3,4-Methylenedioxymethamphetamine, Lysergic Acid Diethylamide, and Metabolites of the Catecholamine Neurotransmitters Are Agonists of a Rat Trace Amine Receptor

    James R. Bunzow;Mark S. Sonders;Seksiri Arttamangkul;Laura M. Harrison

  • Cloning of the cDNA and gene for a human D2 dopamine receptor.

    D K Grandy;M A Marchionni;H Makam;R E Stofko

  • The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.

    David Grandy;M. Litt;L. Allen;J. R. Bunzow

  • Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine

    Marcelo Rubinstein;Tamara J. Phillips;Tamara J. Phillips;James R. Bunzow;Tomás L. Falzone

  • Dopamine D4 Receptor-Knock-Out Mice Exhibit Reduced Exploration of Novel Stimuli

    Stephanie C. Dulawa;David K. Grandy;Malcolm J. Low;Martin P. Paulus

  • Rapid signaling of estrogen in hypothalamic neurons involves a novel G-protein-coupled estrogen receptor that activates protein kinase C

    Jian Qiu;Martha A. Bosch;Sandra C. Tobias;David K. Grandy

  • Locomotor Activity in D2 Dopamine Receptor-Deficient Mice Is Determined by Gene Dosage, Genetic Background, and Developmental Adaptations

    Michele A. Kelly;Marcelo Rubinstein;Tamara J. Phillips;Christina N. Lessov

  • 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone.

    Thomas S Scanlan;Katherine L Suchland;Matthew E Hart;Grazia Chiellini

  • Pituitary Lactotroph Hyperplasia and Chronic Hyperprolactinemia in Dopamine D2 Receptor-Deficient Mice

    Michele A Kelly;Marcelo Rubinstein;Sylvia L Asa;Ge Zhang

  • Orphanin FQ is a functional anti-opioid peptide

    J.S Mogil;J.E Grisel;R.K Reinscheid;O Civelli

  • Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis

    Philip Seeman;David Weinshenker;Remi Quirion;Lalit K. Srivastava

  • Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons.

    Michael J Beckstead;David K Grandy;Kevin Wickman;John T Williams

  • Orphanin FQ/nociceptin: A role in pain and analgesia, but so much more

    Tristan Darland;Mary M. Heinricher;David K. Grandy

  • PCR detection of the TaqA RFLP at the DRD2 locus

    D.K. Grandy;Y. Zhang;O. Civelli

  • Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors

    Tamara Phillips;Kelly J. Brown;Sue Burkhart-Kasch;Charlotte D. Wenger;Charlotte D. Wenger

  • Dopamine D2 Receptor‐Deficient Mice Exhibit Decreased Dopamine Transporter Function but No Changes in Dopamine Release in Dorsal Striatum

    Shelly D. Dickinson;Jilla Sabeti;Gaynor A. Larson;Karen Giardina

Frequent Co-Authors

Malcolm J. Low
Malcolm J. Low University of Michigan–Ann Arbor
Olivier Civelli
Olivier Civelli University of California, Irvine
Marcelo Rubinstein
Marcelo Rubinstein University of Buenos Aires
Nora D. Volkow
Nora D. Volkow National Institutes of Health
Gene-Jack Wang
Gene-Jack Wang National Institutes of Health
Jonathan L. Katz
Jonathan L. Katz National Institute on Drug Abuse
Paul R. Albert
Paul R. Albert Ottawa Hospital
Hubert H. M. Van Tol
Hubert H. M. Van Tol University of Toronto
Pedro A. Jose
Pedro A. Jose George Washington University
Jeffrey S. Mogil
Jeffrey S. Mogil McGill University

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