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Junji Takeda

Junji Takeda

D-Index & Metrics

Molecular Biology

D-Index
76
Citations
19660
World Ranking
1155
National Ranking
95

Overview

Junji Takeda is affiliated with Osaka University in Japan and has an extensive research portfolio spanning the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work primarily explores Molecular Biology, Hematology, Cell Biology, Epidemiology, and Cognitive Neuroscience.

The scientist's research topics cover a range of areas, including:

  • CRISPR and Genetic Engineering
  • Trypanosoma species research and implications
  • Autism Spectrum Disorder Research
  • Lysosomal Storage Disorders Research
  • Acute Myeloid Leukemia Research
  • Hematopoietic Stem Cell Transplantation
  • RNA Research and Splicing

Junji Takeda has contributed to several peer-reviewed publications. Selected recent papers include:

  • Limb-clasping, cognitive deficit and increased vulnerability to kainic acid-induced seizures in neuronal glycosylphosphatidylinositol deficiency mouse models, 2021, Human Molecular Genetics
  • A newly identified gene Ahed plays essential roles in murine haematopoiesis, 2024, Nature Communications
  • 283 Possibility of therapeutic application to autosomal dominant dystrophic epidermolysis bullosa using large deletion genome editing with CRISPR-Cas3, 2020, Journal of Investigative Dermatology
  • Limb-clasping, cognitive deficit and increased vulnerability to kainic acid - induced seizures in neuronal GPI anchor deficiency mouse models, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Inhibition of N-myristoyltransferase Promotes Naive Pluripotency in Mouse and Human Pluripotent Stem Cells, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Takeda include:

  • Hitomi Watanabe
  • Gen Kondoh
  • Shigetoshi Sano
  • Masahiro Tokunaga
  • Chikara Kokubu

The most common publication venues for their work are:

  • Nature Communications
  • Journal of Investigative Dermatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Molecular Genetics
  • HemaSphere

Best Publications

  • Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria.

    Junji Takeda;Toshio Miyata;Kazuyoshi Kawagoe;Yoshiyasu Iida;Yoshiyasu Iida

  • Correction: Stat3 Activation Is Responsible for IL-6–Dependent T Cell Proliferation through Preventing Apoptosis: Generation and Characterization of T Cell–Specific Stat3-Deficient Mice

    Kiyoshi Takeda;Tsuneyasu Kaisho;Nobuaki Yoshida;Junji Takeda

  • Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

    Kosuke Yusa;Roland Rad;Junji Takeda;Allan Bradley

  • Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

    Taiichi Katayama;Kazunori Imaizumi;Naoya Sato;Ko Miyoshi

  • Keratinocyte‐specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

    Shigetoshi Sano;Satoshi Itami;Kiyoshi Takeda;Masahito Tarutani

  • The Cloning of PIG-A, a Component in the Early Step of GPI-Anchor Biosynthesis

    Toshio Miyata;Junji Takeda;Yoshiyasu Iida;Norio Yamada

  • DISRUPTION OF STAT3 REVEALS A CRITICAL ROLE IN BOTH THE INITIATION AND THE PROMOTION STAGES OF EPITHELIAL CARCINOGENESIS

    Keith Syson Chan;Shigetoshi Sano;Kaoru Kiguchi;Joanne Anders

  • Requirement of DNase II for Definitive Erythropoiesis in the Mouse Fetal Liver

    Kohki Kawane;Hidehiro Fukuyama;Gen Kondoh;Junji Takeda

  • Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene.

    M Bessler;P J Mason;P Hillmen;T Miyata

  • A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination

    Shunsuke Kawamoto;Shunsuke Kawamoto;Hitoshi Niwa;Fumi Tashiro;Shigetoshi Sano

  • A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

    Masahiro Yamamoto;Megumi Okuyama;Ji Su Ma;Taishi Kimura

  • Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)

    Masato Matsuki;Fumiyoshi Yamashita;Akemi Ishida-Yamamoto;Keiko Yamada

  • Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development

    Masahito Tarutani;Satoshi Itami;Masaru Okabe;Masahito Ikawa

  • Abnormalities of PIG-A Transcripts in Granulocytes from Patients with Paroxysmal Nocturnal Hemoglobinuria

    Toshio Miyata;Norio Yamada;Yoshiyasu Iida;Junichi Nishimura

  • Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro

    Kazuhiro Yagita;Kyoji Horie;Satoshi Koinuma;Wataru Nakamura

  • p38α Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac Hypertrophic Growth in Response to Pressure Overload

    Kazuhiko Nishida;Osaniu Yamaguchi;Shinichi Hirotani;Shungo Hikoso

  • Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization.

    Gen Kondoh;Hiromasa Tojo;Yuka Nakatani;Nobuyasu Komazawa

  • PDGFRα-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia

    Katsuto Tamai;Takehiko Yamazaki;Takenao Chino;Masaru Ishii

  • Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation.

    Akira Suzuki;Satoshi Itami;Minako Ohishi;Koichi Hamada

  • Raf-1 regulates Rho signaling and cell migration

    Karin Ehrenreiter;Daniela Piazzolla;Vanishree Velamoor;Izabela Sobczak

Frequent Co-Authors

Taroh Kinoshita
Taroh Kinoshita Osaka University
Kosuke Yusa
Kosuke Yusa Kyoto University
Masaru Okabe
Masaru Okabe Osaka University
Jun-ichi Miyazaki
Jun-ichi Miyazaki Osaka University
Kinya Otsu
Kinya Otsu King's College London
Yuichi Endo
Yuichi Endo Fukushima Medical University
Toru Nakano
Toru Nakano Osaka University
Shizuo Akira
Shizuo Akira Osaka University
Toshio Miyata
Toshio Miyata Tohoku University
Yasuo Uchiyama
Yasuo Uchiyama Juntendo University

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