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D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
49138
World Ranking
1790
National Ranking
17

Overview

David Wallach is affiliated with the Weizmann Institute of Science in Israel. Their research spans multiple scientific disciplines primarily within biochemistry, genetics, molecular biology, economics, econometrics, and finance. The subfields of their work include economics and econometrics, molecular biology, immunology, epidemiology, and cancer research.

Their academic output emphasizes various topics such as interferon and immune responses, CRISPR and genetic engineering, autophagy in disease and therapy, health systems, economic evaluations and quality of life, economic and financial impacts of cancer, pharmaceutical economics and policy, and NF-κB signaling pathways.

David Wallach has published in several journals, with recent works appearing in specialized venues including:

  • Cell Death and Differentiation
  • Gynecologic Oncology
  • Cell Reports

Notable recent papers include:

  • "Site-specific ubiquitination of MLKL targets it to endosomes and targets Listeria and Yersinia to the lysosomes," 2022, Cell Death and Differentiation
  • "Accelerating breakthroughs: How a clinical trial fast-track program expands access to critical cancer treatments," 2025, Gynecologic Oncology
  • "Limited activation interdependence and differing patterns of the in vivo effects of IKK1 and IKK2 downstream of NIK," 2025, Cell Reports

Their collaborative network includes frequent co-authors such as Konstantin Bogdanov, Seongmin Yoon, Ankeeta Joshi, Nadia Catti, and Huan Duong.

The interdisciplinary nature of Wallach's research bridges biological sciences with economics, examining complex biological mechanisms alongside health systems and economic policies related to cancer and pharmaceuticals.

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death.

    Mark P Boldin;Tanya M Goncharov;Yury V Goltseve;David Wallach

  • MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.

    Nikolai L. Malinin;Mark P. Boldin;Andrei V. Kovalenko;David Wallach

  • TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS

    D. Wallach;E. E. Varfolomeev;N. L. Malinin;Yuri V. Goltsev

  • Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally

    Eugene E Varfolomeev;Marcus Schuchmann;Victor Luria;Nuchanard Chiannilkulchai

  • The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination.

    Andrew Kovalenko;Christine Chable-Bessia;Giuseppina Cantarella;Giuseppina Cantarella;Alain Israël

  • A NOVEL PROTEIN THAT INTERACTS WITH THE DEATH DOMAIN OF FAS/APO1 CONTAINS A SEQUENCE MOTIF RELATED TO THE DEATH DOMAIN

    Mark P. Boldin;Eugene E. Varfolomeev;Zeev Pancer;Igor L. Mett

  • Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

    D Aderka;H Engelmann;Y Maor;C Brakebusch

  • Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors.

    H Engelmann;D Novick;D Wallach

  • Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease

    G. Boka;P. Anglade;D. Wallach;F. Javoy-Agid

  • A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity.

    H Engelmann;D Aderka;M Rubinstein;D Rotman

  • Elevated tumour necrosis factor-alpha (TNF-alpha) biological activity in psoriatic skin lesions.

    P. Ettehadi;M. W. Greaves;D. Wallach;D. Aderka

  • Recruitment of the IKK Signalosome to the p55 TNF Receptor: RIP and A20 Bind to NEMO (IKKγ) upon Receptor Stimulation

    Si Qing Zhang;Andrew Kovalenko;Giuseppina Cantarella;David Wallach

  • Soluble cytokine receptors are present in normal human urine.

    Daniela Novick;Hartmut Engelmann;David Wallach;Menachem Rubinstein

  • Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.

    Y Nophar;O Kemper;C Brakebusch;H Englemann

  • Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.

    H Engelmann;H Holtmann;C Brakebusch;Y S Avni

  • Programmed necrosis in inflammation: Toward identification of the effector molecules

    David Wallach;Tae-Bong Kang;Christopher P. Dillon;Douglas R. Green

  • Self-association of the Death Domains of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 Effects

    Mark P. Boldin;Igor L. Mett;Eugene E. Varfolomeev;Irina Chumakov

  • Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies.

    Jean Weissenbach;Yuti Chernajovsky;Menachem Zeevi;Lester Shulman

  • Preferential effect of gamma interferon on the synthesis of HLA antigens and their mRNAs in human cells.

    David Wallach;Marc Fellous;Michel Revel

Frequent Co-Authors

Michel Revel
Michel Revel Weizmann Institute of Science
Cord Brakebusch
Cord Brakebusch University of Copenhagen
Menachem Rubinstein
Menachem Rubinstein Weizmann Institute of Science
Daniela Novick
Daniela Novick Weizmann Institute of Science
Adi Kimchi
Adi Kimchi Weizmann Institute of Science
Zelig Eshhar
Zelig Eshhar Weizmann Institute of Science
Marshall S. Horwitz
Marshall S. Horwitz University of Washington
Klaus Resch
Klaus Resch Hannover Medical School
Douglas R. Green
Douglas R. Green St. Jude Children's Research Hospital
Marc Fellous
Marc Fellous Bayer Pharmaceuticals

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