What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Biochemistry, Cyclooxygenase, Enzyme, Prostaglandin and Pharmacology.
Many of his studies on Biochemistry involve topics that are commonly interrelated, such as Molecular biology.
His Cyclooxygenase study integrates concerns from other disciplines, such as Central nervous system, Microglia, Immune system, Pathology and Isozyme.
His study in the field of Lipid peroxidation also crosses realms of Leukotriene.
The Prostaglandin study combines topics in areas such as Protein primary structure, Serine, Arachidonic acid, Complementary DNA and Regulation of gene expression.
His work carried out in the field of Pharmacology brings together such families of science as Inflammation, Aspirin and Toxicity.
His most cited work include:
- Cyclooxygenases: Structural, cellular, and molecular biology (2358 citations)
- Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2 (1792 citations)
- Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. (1160 citations)
What are the main themes of his work throughout his whole career to date?
David L. DeWitt mainly investigates Biochemistry, Cyclooxygenase, Enzyme, Molecular biology and Prostaglandin.
David L. DeWitt has researched Cyclooxygenase in several fields, including Fruit extracts, Traditional medicine and Pharmacology.
His study looks at the relationship between Pharmacology and topics such as Aspirin, which overlap with Ibuprofen.
His Enzyme research is multidisciplinary, incorporating elements of Transcriptional regulation, Prostanoid and Cytotoxicity.
He interconnects Prostaglandin E2, Endocrinology, Internal medicine, Endoplasmic reticulum and Peptide sequence in the investigation of issues within Molecular biology.
His biological study spans a wide range of topics, including Gene, Biosynthesis, Stimulation, Monocyte and Cell biology.
He most often published in these fields:
- Biochemistry (46.83%)
- Cyclooxygenase (34.92%)
- Enzyme (34.13%)
What were the highlights of his more recent work (between 2005-2020)?
- Biochemistry (46.83%)
- Lipid peroxidation (10.32%)
- Cyclooxygenase (34.92%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Biochemistry, Lipid peroxidation, Cyclooxygenase, Enzyme and Traditional medicine.
Cell growth, IC50, Linoleic acid, Prostaglandin and Arachidonic acid are among the areas of Biochemistry where the researcher is concentrating his efforts.
David L. DeWitt works mostly in the field of Prostaglandin, limiting it down to topics relating to Matrix metalloproteinase and, in certain cases, Molecular biology, as a part of the same area of interest.
His research integrates issues of Inhibitory postsynaptic potential, Nonsteroidal, Prostaglandin endoperoxide and Glycosphingolipid in his study of Cyclooxygenase.
He combines subjects such as Integral membrane protein and Biophysics with his study of Enzyme.
His Traditional medicine research integrates issues from Fruit extracts, Inflammation and Pharmacognosy.
Between 2005 and 2020, his most popular works were:
- Impact of Alkyl Esters of Caffeic and Ferulic Acids on Tumor Cell Proliferation, Cyclooxygenase Enzyme, and Lipid Peroxidation (112 citations)
- Anthocyanin content, lipid peroxidation and cyclooxygenase enzyme inhibitory activities of sweet and sour cherries. (91 citations)
- The 19-amino acid cassette of cyclooxygenase-2 mediates entry of the protein into the endoplasmic reticulum-associated degradation system (87 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Biochemistry, Enzyme, Enzyme assay, Cell growth and IC50.
His studies in Biochemistry integrate themes in fields like Agrocybe, Pharmacology and Black poplar.
Particularly relevant to Cyclooxygenase is his body of work in Enzyme.
The various areas that David L. DeWitt examines in his Cyclooxygenase study include Lipid peroxidation and Antioxidant.
His work deals with themes such as Angiogenesis, Docking, Arachidonic acid, Lipoxygenase and Biological activity, which intersect with Cell growth.
His IC50 research is multidisciplinary, relying on both Mushroom, Edible mushroom, Anti-inflammatory and Linoleic acid.
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