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Christine M. Disteche

Christine M. Disteche

D-Index & Metrics

Genetics

D-Index
87
Citations
30295
World Ranking
1205
National Ranking
575

Overview

Christine M. Disteche is affiliated with the University of Washington in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant number of publications in molecular biology and genetics subfields. The scientist's work also intersects with cancer research, biophysics, and pediatrics, perinatology, and child health.

Their research topics cover a wide range of areas including:

  • Single-cell and spatial transcriptomics
  • Genomics and chromatin dynamics
  • Genetic and clinical aspects of sex determination and chromosomal abnormalities
  • RNA research and splicing
  • CRISPR and genetic engineering
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer

Christine M. Disteche has contributed to various recent scientific papers, including:

  • "Systematic reconstruction of cellular trajectories across mouse embryogenesis," 2022, published in Nature Genetics
  • "A single-cell time-lapse of mouse prenatal development from gastrula to birth," 2024, published in Nature
  • "Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project," 2023, published in Molecular Cell
  • "X-chromosome regulation and sex differences in brain anatomy," 2020, published in Neuroscience & Biobehavioral Reviews
  • "Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome," 2020, published in Nature Communications

The scientist frequently collaborates with other researchers. Notable coauthors include Xinxian Deng, William Stafford Noble, Jay Shendure, He Fang, and Galina N. Filippova.

Christine M. Disteche has published in several venues throughout their career. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ENCODE Datasets
  • Genome Biology
  • Biology of Sex Differences
  • Nature Genetics

Best Publications

  • A comparative encyclopedia of DNA elements in the mouse genome

    Feng Yue;Feng Yue;Yong Cheng;Alessandra Breschi;Jeff Vierstra

  • The molecular basis of the human serum paraoxonase activity polymorphism.

    Richard Humbert;David A. Adler;Christine M. Disteche;Christopher Hassett

  • CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome

    R. Cutler Allen;Richard J. Armitage;Mary Ellen Conley;Howard Rosenblatt

  • DNA deletion associated with hereditary neuropathy with liability to pressure palsies

    Phillip F. Chance;Phillip F. Chance;Mary Kathryn Alderson;Mary Kathryn Alderson;Mary Kathryn Alderson;Kathleen A. Leppig;M.William Lensch

  • Down syndrome phenotypes: the consequences of chromosomal imbalance

    J R Korenberg;X N Chen;R Schipper;Z Sun

  • The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB–binding protein

    Julian Borrow;Vincent P. Stanton;J. Michael Andresen;Reinhard Becher

  • A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility

    Darren A. Cusanovich;Andrew J. Hill;Delasa Aghamirzaie;Riza M. Daza

  • CTCF physically links cohesin to chromatin

    Eric D. Rubio;David J. Reiss;Piri L. Welcsh;Christine M. Disteche

  • Dosage compensation in mammals: fine-tuning the expression of the X chromosome

    Edith Heard;Christine M. Disteche

  • Massively multiplex single-cell Hi-C

    Vijay Ramani;Xinxian Deng;Ruolan Qiu;Kevin L Gunderson

  • Minor Xp21 chromosome deletion in a male associated with expression of duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa, and McLeod syndrome

    Francke U;Ochs Hd;de Martinville B;Giacalone J

  • Dosage compensation of the active X chromosome in mammals.

    Di Kim Nguyen;Christine M Disteche

  • The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned

    Richa Saxena;Laura G. Brown;Trevor Hawkins;Raaji K. Alagappan

  • The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumor-inhibitory activity.

    Gregory D. Plowman;Janell M. Green;Vicki L. McDonald;Michael G. Neubauer

  • Leukemia of Large Granular Lymphocytes: Association with Clonal Chromosomal Abnormalities and Autoimmune Neutropenia, Thrombocytopenia, and Hemolytic Anemia

    Thomas P. Loughran;Marshall E. Kadin;Gordon Starkebaum;Janis L. Abkowitz

  • Global survey of escape from X inactivation by RNA-sequencing in mouse

    Fan Yang;Tomas Babak;Jay Shendure;Christine M. Disteche

  • βig-h3: A Transforming Growth Factor-β-Responsive Gene Encoding a Secreted Protein That Inhibits Cell Attachment In Vitro and Suppresses the Growth of CHO Cells in Nude Mice

    John Skonier;Kelly Bennett;Victoria Rothwell;Steve Kosowski

  • Genes that escape from X inactivation.

    Joel B. Berletch;Fan Yang;Jun Xu;Laura Carrel

  • X chromosome regulation: diverse patterns in development, tissues and disease

    Xinxian Deng;Joel B. Berletch;Di K. Nguyen;Christine M. Disteche

  • Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10.

    Allan E. Karlsen;William A. Hagopian;Catherine E. Grubin;Syamalima Dube

Frequent Co-Authors

Jay Shendure
Jay Shendure University of Washington
William Stafford Noble
William Stafford Noble University of Washington
Verne M. Chapman
Verne M. Chapman Roswell Park Cancer Institute
George M. Martin
George M. Martin University of Washington
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Jennifer A. Marshall Graves
Jennifer A. Marshall Graves La Trobe University
Stuart H. Orkin
Stuart H. Orkin Harvard University

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