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Biology and Biochemistry

D-Index
85
Citations
24273
World Ranking
3173
National Ranking
1600

Overview

Clement E. Furlong is affiliated with the University of Washington in the United States. Their research primarily focuses on fields related to Biochemistry, Genetics and Molecular Biology, with significant contributions in Clinical Biochemistry, Molecular Biology, Pharmacology, Health, Toxicology and Mutagenesis, and Environmental Chemistry.

Their work covers a range of specific topics which include:

  • Paraoxonase enzyme and polymorphisms
  • Air Quality and Health Impacts
  • Biosensors and Analytical Detection
  • Coenzyme Q10 studies and effects
  • Heat shock proteins research
  • Pesticide Exposure and Toxicity
  • Cholinesterase and Neurodegenerative Diseases

Furlong's recent papers reflect a diverse research portfolio. Key publications include:

  • Health consequences of exposure to aircraft contaminated air and fume events: a narrative review and medical protocol for the investigation of exposed aircrew and passengers, 2023, Environmental Health
  • Carbon nanotube-based thin-film resistive sensor for point-of-care screening of tuberculosis, 2020, Biomedical Microdevices
  • Paraoxonase-1 (PON1) Status Analysis Using Non-Organophosphate Substrates, 2021, Current Protocols
  • Highly Sensitive Immunoresistive Sensor for Point-Of-Care Screening for COVID-19, 2022, Biosensors
  • Underway measurement of cyanobacterial microcystins using a surface plasmon resonance sensor on an autonomous underwater vehicle, 2024, Limnology and Oceanography Methods

The scientist has published multiple times in several venues, with frequent publications in:

  • Environmental Health
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Limnology and Oceanography Methods
  • Biomedical Microdevices
  • Current Protocols

Collaboration plays a role in their research, with frequent co-authors including:

  • Judit Marsillach
  • Rebecca J. Richter
  • Lucio G. Costa
  • Scott D. Soelberg
  • Jacqueline M. Garrick

Best Publications

  • Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

    Diana M. Shih;Lingjie Gu;Yu Rong Xia;Mohamad Navab

  • The molecular basis of the human serum paraoxonase activity polymorphism.

    Richard Humbert;David A. Adler;Christine M. Disteche;Christopher Hassett

  • The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin

    Holly G. Davies;Rebecca J. Richter;Matthew Keifer;Clarence A. Broomfield

  • Modulation of paraoxonase (PON1) activity

    Lucio G. Costa;Annabella Vitalone;Toby B. Cole;Clement E. Furlong

  • Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease

    Christian Besler;Kathrin Heinrich;Lucia Rohrer;Carola Doerries

  • Association of in Utero Organophosphate Pesticide Exposure and Fetal Growth and Length of Gestation in an Agricultural Population

    Brenda Eskenazi;Kim Harley;Asa Bradman;Erin K Weltzien

  • Effects of 5' regulatory-region polymorphisms on paraoxonase-gene (PON1) expression.

    Victoria H. Brophy;Rachel L. Jampsa;James B. Clendenning;Laura A. McKinstry

  • Yeast gene required for spindle pole body duplication: homology of its product with Ca2+-binding proteins.

    Peter Baum;Clement Furlong;Breck Byers

  • Paraoxonase (PON1) Phenotype Is a Better Predictor of Vascular Disease Than Is PON1192 or PON155 Genotype

    Gail Pairitz Jarvik;Laura S. Rozek;Victoria H. Brophy;Thomas S. Hatsukami

  • Determination of paraoxonase (PON1) status requires more than genotyping.

    Rebecca J. Richter;Clement E. Furlong

  • Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates.

    Jessica G. Young;Brenda Eskenazi;Eleanor A. Gladstone;Asa Bradman

  • Catalytic efficiency determines the in-vivo efficacy of PON1 for detoxifying organophosphorus compounds

    Wan-Fen Li;Lucio G. Costa;Rebecca J. Richter;Tamara Hagen

  • Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence.

    Christopher Hassett;Rebecca J. Richter;Richard Humbert;Christine Chapline

  • Functional Genomics of the Paraoxonase (PON1) Polymorphisms: Effects on Pesticide Sensitivity, Cardiovascular Disease, and Drug Metabolism

    Lucio G. Costa;Toby B. Cole;Gail P. Jarvik;Clement E. Furlong

  • Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

    Folkert W. Asselbergs;Yiran Guo;Yiran Guo;Erik P A Van Iperen;Suthesh Sivapalaratnam

  • Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase/arylesterase

    Clement E. Furlong;Rebecca J. Richter;Sharon L. Seidel;Lucio G. Costa

  • Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

    Richa Saxena;Richa Saxena;Clara C. Elbers;Clara C. Elbers;Yiran Guo;Inga Peter

  • Role of genetic polymorphism of human plasma paraoxonase/arylesterase in hydrolysis of the insecticide metabolites chlorpyrifos oxon and paraoxon.

    C E Furlong;R J Richter;S L Seidel;A G Motulsky

  • Vitamin C and E Intake Is Associated With Increased Paraoxonase Activity

    Gail P. Jarvik;Nancey Trevanian Tsai;Laura A. McKinstry;Roohi Wani

  • A commercial solution for surface plasmon sensing

    Jose Melendez;Richard Carr;Dwight U Bartholomew;Kari Kukanskis

Frequent Co-Authors

Lucio G. Costa
Lucio G. Costa University of Washington
Gail P. Jarvik
Gail P. Jarvik University of Washington
Paul I. W. de Bakker
Paul I. W. de Bakker Vertex Pharmaceuticals (United Kingdom)
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Alan R. Shuldiner
Alan R. Shuldiner University of Maryland, Baltimore
Brendan J. Keating
Brendan J. Keating University of Pennsylvania
Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Aldons J. Lusis
Aldons J. Lusis University of California, Los Angeles
George M. Martin
George M. Martin University of Washington

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