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Biology and Biochemistry

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74
Citations
16893
World Ranking
5703
National Ranking
2701

Medicine

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74
Citations
17196
World Ranking
19484
National Ranking
9699

Overview

Ian S. Zagon is affiliated with Pennsylvania State University in the United States and has contributed extensively to the field of medicine, with a focus on ocular surface disorders and related physiological mechanisms.

The research primarily addresses issues involving the ocular surface, diabetes-related complications, and neurological aspects of disease. Main topics of study in this scientist's work include:

  • Ocular Surface and Contact Lens
  • Multiple Sclerosis Research Studies
  • Neuropeptides and Animal Physiology
  • Pain Mechanisms and Treatments
  • Glaucoma and retinal disorders
  • Proteoglycans and glycosaminoglycans research
  • Immune Cell Function and Interaction

Ian S. Zagon's publications span core medical areas with a strong emphasis on ocular and neurological health. Frequent publication venues include:

  • Experimental Biology and Medicine
  • Journal of Diabetes and Clinical Research
  • Medical Research Archives
  • Experimental and Therapeutic Medicine
  • Biochemical Pharmacology

The scientist has collaborated frequently with several co-authors, enhancing the interdisciplinary nature of their research. Notable co-authors include:

  • Patricia J. McLaughlin
  • Joseph W. Sassani
  • Indira Purushothaman
  • Gary A. Thomas
  • Laura Odom

Significant recent papers authored or co-authored by Ian S. Zagon encompass the following:

  • Dysregulation of the OGF-OGFr pathway correlates with elevated serum OGF and ocular surface complications in the diabetic rat, 2020, Experimental Biology and Medicine
  • Blockade of OGFr delays the onset and reduces the severity of diabetic ocular surface complications, 2020, Experimental Biology and Medicine
  • Ocular surface complications result from dysregulation of the OGF-OGFr signaling pathway in female diabetic rats, 2021, Experimental and Therapeutic Medicine
  • Ocular surface complications in diabetes: The interrelationship between insulin and enkephalin, 2021, Biochemical Pharmacology
  • Low-dose naltrexone reduced anxiety in persons with multiple sclerosis during the COVID-19 pandemic, 2022, International Immunopharmacology

The subfields of study related to the scientist's work reveal a multidisciplinary approach within medicine, including:

  • Public Health, Environmental and Occupational Health
  • Pathology and Forensic Medicine
  • Cellular and Molecular Neuroscience
  • Neurology
  • Physiology

Best Publications

  • The biology of the opioid growth factor receptor (OGFr).

    Ian S Zagon;Michael F Verderame;Patricia J McLaughlin

  • The effect of potassium on neuronal differentiation in cultures of dissociated newborn rat cerebellum

    Robert S. Lasher;Ian S. Zagon

  • Brain spectrin(240/235) and brain spectrin(240/235E): two distinct spectrin subtypes with different locations within mammalian neural cells.

    B M Riederer;I S Zagon;S R Goodman

  • Endogenous opioid systems regulate cell proliferation in the developing rat brain

    Ian S. Zagon;Patricia J. MacLaughlin

  • Increased brain size and cellular content in infant rats treated with an opiate antagonist

    Ian S. Zagon;Patricia J. McLaughlin

  • Naltrexone modulates tumor response in mice with neuroblastoma

    Ian S. Zagon;Patricia J. McLaughlin

  • Identification of a spectrin-like protein in nonerythroid cells.

    Steven R. Goodman;Ian S. Zagon;Robert R. Kulikowski

  • Identification of opioid peptides regulating proliferation of neurons and glia in the developing nervous system.

    Ian S. Zagon;Patricia J. McLaughlin

  • Spectrin and related molecules

    Steven R. Goodman;Keith E. Krebs;Carol F. Whitfield;Beat M. Riederer

  • Spectrin subtypes in mammalian brain: an immunoelectron microscopic study

    IS Zagon;R Higbee;BM Riederer;SR Goodman

  • Brain spectrin: of mice and men.

    Steven R. Goodman;Warren E. Zimmer;Mary Blair Clark;Ian S. Zagon

  • Low-Dose Naltrexone Therapy Improves Active Crohn's Disease

    Jill P. Smith;Heather Stock;Sandra Bingaman;David Mauger

  • Naltrexone modulates body and brain development in rats: A role for endogenous opioid systems in growth

    Ian S. Zagon;Patricia J. McLaughlin

  • Opioids and the apoptotic pathway in human cancer cells

    Ian S Zagon;Patricia J McLaughlin

  • Distribution of Enkephalin Immunoreactivity in Germinative Cells of Developing Rat Cerebellum

    Ian S. Zagon;Randall E. Rhodes;Patricia J. McLaughlin

  • Endogenous opioids regulate dendritic growth and spine formation in developing rat brain.

    Kurt F. Hauser;Patricia J. McLaughlin;Ian S. Zagon

  • Endogenous opioid systems and the regulation of dendritic growth and spine formation

    Kurt F. Hauser;Patricia J. McLaughlin;Ian S. Zagon

  • Opioid receptors and endogenous opioids in diverse human and animal cancers.

    Ian S. Zagon;Patricia J. McLaughlin;Steven R. Goodman;Randy E. Rhodes

  • Opioid growth factor modulates angiogenesis

    Ian Zagon;John Blebea;Patricia McLaughlin

  • Identification of gastrin as a growth peptide in human pancreatic cancer

    J. P. Smith;A. P. Fantaskey;Guozhen Liu;I. S. Zagon

Frequent Co-Authors

Patricia J. McLaughlin
Patricia J. McLaughlin Pennsylvania State University
Steven R. Goodman
Steven R. Goodman University of Tennessee Health Science Center
Beat M. Riederer
Beat M. Riederer University of Lausanne
David T. Mauger
David T. Mauger Pennsylvania State University
Anthony E. Pegg
Anthony E. Pegg Pennsylvania State University
David M. Goldenberg
David M. Goldenberg Immunomedics (United States)
William A. Banks
William A. Banks University of Washington
Arne Schousboe
Arne Schousboe University of Copenhagen
Lars Olson
Lars Olson Karolinska Institute
Katsuhiko Mikoshiba
Katsuhiko Mikoshiba ShanghaiTech University

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