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Biology and Biochemistry

D-Index
44
Citations
11679
World Ranking
19212
National Ranking
7848

Overview

Joshua M. Kaplan is affiliated with Harvard University in the United States. Their research spans multiple scientific fields, with a significant focus on biochemistry, genetics, and molecular biology, complemented by work in medicine and neuroscience. Their studies investigate various biological processes, including aging, molecular biology, cellular and molecular neuroscience, endocrine and autonomic systems, and social psychology.

Their scholarly output encompasses numerous topics, reflecting a broad interest in genetic and neurobiological systems. Key areas of work include genetics, aging, and longevity in model organisms; circadian rhythm and melatonin; photoreceptor and optogenetics research; neuroendocrine regulation and behavior; systemic lupus erythematosus research; neurobiology and insect physiology research; and neuroscience and neuropharmacology research.

Joshua M. Kaplan has contributed to a range of recent publications. Some notable papers include:

  • Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial, 2021, The Lancet
  • Presynaptic Gαo (GOA-1) signals to depress command neuron excitability and allow stretch-dependent modulation of egg laying in Caenorhabditis elegans, 2021, Genetics
  • Male pheromones modulate synaptic transmission at the C. elegans neuromuscular junction in a sexually dimorphic manner, 2021, eLife
  • Caenorhabditis elegans junctophilin has tissue-specific functions and regulates neurotransmission with extended-synaptotagmin, 2021, Genetics
  • MRI demonstration of gadolinium deposition in bone after monthly triple-dose gadopentetate dimeglumine and correlation with frequency of hypophosphatemia, 2020, Clinical Imaging

They have frequently published in several scientific journals and venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Society of Nephrology
  • Genetics
  • eLife
  • Proceedings of the National Academy of Sciences

Joshua M. Kaplan maintains ongoing collaborations with several researchers. Notable frequent co-authors include Stephen Nurrish, Evan L. Ardiel, Jian Zhao, Kang-Ying Qian, and Wan-Xin Zeng.

Best Publications

  • A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans.

    J M Kaplan;H R Horvitz

  • Synaptic code for sensory modalities revealed by C. elegans GLR-1 glutamate receptor.

    Anne C. Hart;Shannon Sims;Joshua M. Kaplan

  • Systematic analysis of genes required for synapse structure and function.

    Derek Sieburth;Queelim Ch'ng;Michael Dybbs;Masoud Tavazoie;Masoud Tavazoie

  • Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegans

    Laurent Ségalat;Daniel A. Elkes;Joshua M. Kaplan

  • Serotonin inhibition of synaptic transmission: Galpha(0) decreases the abundance of UNC-13 at release sites.

    Stephen Nurrish;Laurent Ségalat;Joshua M. Kaplan

  • Ubiquitin and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic elements in C. elegans

    Michelle Burbea;Lars Dreier;Jeremy S. Dittman;Maria E. Grunwald

  • FACILITATION OF SYNAPTIC TRANSMISSION BY EGL-30 GQALPHA AND EGL-8 PLCBETA : DAG BINDING TO UNC-13 IS REQUIRED TO STIMULATE ACETYLCHOLINE RELEASE

    Mark R Lackner;Stephen J Nurrish;Joshua M Kaplan

  • Functional genomic analysis of RNA interference in C. elegans

    John K. Kim;Harrison W. Gabel;Ravi S. Kamath;Muneesh Tewari

  • PKC-1 regulates secretion of neuropeptides.

    Derek Sieburth;Jon M Madison;Joshua M Kaplan

  • LIN-10 Is a Shared Component of the Polarized Protein Localization Pathways in Neurons and Epithelia

    Christopher Rongo;Charles W Whitfield;Avital Rodal;Stuart K Kim

  • CaMKII regulates the density of central glutamatergic synapses in vivo

    Christopher Rongo;Joshua M. Kaplan

  • Distinct signaling pathways mediate touch and osmosensory responses in a polymodal sensory neuron.

    Anne C. Hart;Jamie Kass;Jonathan E. Shapiro;Joshua M. Kaplan

  • Signal transduction in the Caenorhabditis elegans nervous system.

    Cornelia I. Bargmann;Joshua M. Kaplan

  • The EGL-3 Proprotein Convertase Regulates Mechanosensory Responses of Caenorhabditis elegans

    Jamie Kass;Tija C. Jacob;Peter Kim;Joshua M. Kaplan

  • The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions

    David J. Simon;Jon M. Madison;Annie L. Conery;Katherine L. Thompson-Peer

  • The EGL-21 Carboxypeptidase E Facilitates Acetylcholine Release at Caenorhabditis elegans Neuromuscular Junctions

    Tija C. Jacob;Joshua M . Kaplan

  • Factors regulating the abundance and localization of synaptobrevin in the plasma membrane

    Jeremy S. Dittman;Joshua M. Kaplan

  • Antagonistic Regulation of Synaptic Vesicle Priming by Tomosyn and UNC-13

    Jason M. McEwen;Jon M. Madison;Michael Dybbs;Joshua M. Kaplan

  • UNC-13 Interaction with Syntaxin Is Required for Synaptic Transmission

    Jon M. Madison;Stephen Nurrish;Joshua M. Kaplan

  • The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant.

    J M Kaplan;G Mardon;J M Bishop;H E Varmus

Frequent Co-Authors

Gary Ruvkun
Gary Ruvkun Harvard University
Marc Vidal
Marc Vidal Harvard University
Yishi Jin
Yishi Jin University of California, San Diego
Ruslan I. Sadreyev
Ruslan I. Sadreyev Harvard University
Andrew D. Chisholm
Andrew D. Chisholm University of California, San Diego
William R Schafer
William R Schafer MRC Laboratory of Molecular Biology
John Ngai
John Ngai University of California, Berkeley
David E. Hill
David E. Hill Harvard University
Stuart K. Kim
Stuart K. Kim Stanford University
David Simon
David Simon Beth Israel Deaconess Medical Center

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