D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 67 Citations 14,128 302 World Ranking 5303 National Ranking 118

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

His primary areas of study are Heparan sulfate, Biochemistry, Cell biology, Extracellular matrix and Pathology. His work carried out in the field of Heparan sulfate brings together such families of science as Sulfation, Glomerular basement membrane, Endocrinology and Fibroblast growth factor. His work deals with themes such as Epitope and Molecular biology, which intersect with Biochemistry.

His Cell biology research incorporates elements of Chondroitin sulfate, Chondroitin and Glycosaminoglycan. His study in Extracellular matrix is interdisciplinary in nature, drawing from both Biomedical engineering, Cell adhesion molecule and Anatomy. His work is dedicated to discovering how Pathology, Podocyte are connected with Immortalised cell line, CD31, Mesangial cell and Matrigel and other disciplines.

His most cited work include:

  • Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity (467 citations)
  • Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate (437 citations)
  • Increased angiogenesis and blood vessel maturation in acellular collagen-heparin scaffolds containing both FGF2 and VEGF. (344 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Heparan sulfate, Biochemistry, Cell biology, Pathology and Extracellular matrix. His research integrates issues of Epitope, Molecular biology, Sulfation and Fibroblast growth factor in his study of Heparan sulfate. Toin H. van Kuppevelt has researched Fibroblast growth factor in several fields, including Endocrinology and Growth factor.

His studies in Cell biology integrate themes in fields like Cell, Glomerular basement membrane and Immunology. The Pathology study which covers Ovarian cancer that intersects with Stromal cell. His studies deal with areas such as Tissue engineering, Biomedical engineering, Elastin, Cancer research and Anatomy as well as Extracellular matrix.

He most often published in these fields:

  • Heparan sulfate (32.33%)
  • Biochemistry (28.00%)
  • Cell biology (22.67%)

What were the highlights of his more recent work (between 2016-2021)?

  • Extracellular matrix (17.33%)
  • Heparan sulfate (32.33%)
  • Regeneration (7.00%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Extracellular matrix, Heparan sulfate, Regeneration, Tissue engineering and Cancer research. His Extracellular matrix research integrates issues from RNA, RNA extraction, Computational biology and Pathology. His Heparan sulfate research incorporates themes from Sulfation, Cell biology and Epitope, Antibody, Phage display.

His Sulfation study incorporates themes from Endocrinology, Perlecan, Dermatan sulfate, Immunology and Internal medicine. The study incorporates disciplines such as Fetal skin, Regenerative medicine, Surgery and Postnatal growth in addition to Tissue engineering. His Chondroitin sulfate study contributes to a more complete understanding of Biochemistry.

Between 2016 and 2021, his most popular works were:

  • Chemotherapeutic drug delivery by tumoral extracellular matrix targeting. (45 citations)
  • Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 (34 citations)
  • Tissue Engineering of the Urethra: A Systematic Review and Meta-analysis of Preclinical and Clinical Studies. (34 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary areas of investigation include Extracellular matrix, Cell biology, Heparan sulfate, Cancer research and Molecular biology. The concepts of his Extracellular matrix study are interwoven with issues in Myofibroblast, Extracellular, Nintedanib, Transforming growth factor and Cell type. The various areas that he examines in his Cell biology study include Cell growth, Ligand, Temozolomide, RNA interference and CCR8.

As a part of the same scientific family, Toin H. van Kuppevelt mostly works in the field of Heparan sulfate, focusing on Sulfation and, on occasion, Cell, Gene, Epitope, Antibody and Phage display. His Cancer research study combines topics from a wide range of disciplines, such as Fibrosis, Fibroblast, Dermis and Targeted drug delivery. Toin H. van Kuppevelt combines subjects such as Xylosyltransferase, Mutant, Transfection, Gene targeting and Gene silencing with his study of Molecular biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity

Helena C. Christianson;Katrin J. Svensson;Toin H. van Kuppevelt;Jin-Ping Li.
Proceedings of the National Academy of Sciences of the United States of America (2013)

732 Citations

Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate

Heidi Barth;Christiane Schäfer;Mohammed I. Adah;Fuming Zhang.
Journal of Biological Chemistry (2003)

647 Citations

Increased angiogenesis and blood vessel maturation in acellular collagen-heparin scaffolds containing both FGF2 and VEGF.

Suzan T.M. Nillesen;Paul J. Geutjes;Ronnie Wismans;Joost Schalkwijk.
Biomaterials (2007)

528 Citations

The performance of human dental pulp stem cells on different three-dimensional scaffold materials.

Weibo Zhang;X. Frank Walboomers;Toin H. van Kuppevelt;Willeke F. Daamen.
Biomaterials (2006)

281 Citations

Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro.

Job L.C van Susante;Jeroen Pieper;Pieter Buma;Toin H van Kuppevelt.
Biomaterials (2001)

248 Citations

Chondroitin 6-sulphate synthesis is up-regulated in injured CNS, induced by injury-related cytokines and enhanced in axon-growth inhibitory glia.

Francesca Properzi;Daniela Carulli;Richard A Asher;Elizabeth Muir.
European Journal of Neuroscience (2005)

245 Citations

Large, tissue-regulated domain diversity of heparan sulfates demonstrated by phage display antibodies.

Michel A.B.A. Dennissen;Guido J. Jenniskens;Martijn Pieffers;Elly M.M. Versteeg.
Journal of Biological Chemistry (2002)

229 Citations

Parietal Epithelial Cells Participate in the Formation of Sclerotic Lesions in Focal Segmental Glomerulosclerosis

Bart Smeets;Christoph Kuppe;Eva Maria Sicking;Astrid Fuss.
Journal of The American Society of Nephrology (2011)

219 Citations

Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum

Theo G.M.F. Gorgels;Xiaofeng Hu;George L. Scheffer;Allard C. van der Wal.
Human Molecular Genetics (2005)

200 Citations

Cross-linked type I and type II collagenous matrices for the repair of full-thickness articular cartilage defects--a study in rabbits.

Pieter Buma;Jeroen S. Pieper;Tony van Tienen;Job L.C. van Susante.
Biomaterials (2003)

184 Citations

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