Malcolm Lyon

Overview

Best Publications

• Structure and function of heparan sulphate proteoglycans

  John T Gallagher;Malcolm Lyon;William P Steward

  667
  Citations

• Endocan or endothelial cell specific molecule-1 (ESM-1) : A potential novel endothelial cell marker and a new target for cancer therapy

  Stéphane Sarrazin;E. Adam;M. Lyon;F. Depontieu

  413
  Citations

• Interaction of hepatocyte growth factor with heparan sulfate : elucidation of the major heparan sulfate structural determinants

  Malcolm Lyon;Jon A Deakin;K Mizuno;T Nakamura

  408
  Citations

• The Interaction of the Transforming Growth Factor-βs with Heparin/Heparan Sulfate Is Isoform-specific

  Malcolm Lyon;Graham Rushton;John T. Gallagher

  369
  Citations

• Liver heparan sulfate structure. A novel molecular design

  Malcolm Lyon;Jon A Deakin;John T Gallagher

  320
  Citations

• Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration

  Aneta J. Pockert;Stephen M. Richardson;Christine L. Le Maitre;Malcolm Lyon

  307
  Citations

• Endocan Is a Novel Chondroitin Sulfate/Dermatan Sulfate Proteoglycan That Promotes Hepatocyte Growth Factor/Scatter Factor Mitogenic Activity

  David Béchard;Thaibaut Gentina;Maryse Delehedde;Arnaud Scherpereel

  303
  Citations

• HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1

  Kenji Uchimura;Megumi Morimoto-Tomita;Annette Bistrup;Jessica Li

  290
  Citations

• A new map of glycosaminoglycan and C3b binding sites on factor H.

  Christoph Q. Schmidt;Andrew P. Herbert;David Kavanagh;Carina Gandy

  259
  Citations

• The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse.

  Catherine L.R. Merry;Simon L. Bullock;Daniel C. Swan;Alison C. Backen

  228
  Citations

• Hepatocyte growth factor/scatter factor binds with high affinity to dermatan sulfate

  Malcolm Lyon;Jon A. Deakin;Hassan Rahmoune;David G. Fernig

  190
  Citations

• BIO-SPECIFIC SEQUENCES AND DOMAINS IN HEPARAN SULPHATE AND THE REGULATION OF CELL GROWTH AND ADHESION

  Malcolm Lyon;John T. Gallagher

  189
  Citations

• Sulphated proteoglycan is required for collecting duct growth and branching but not nephron formation during kidney development

  Jamie Davies;Malcolm Lyon;John Gallagher;David Garrod

  184
  Citations

• Heparan sulfate undergoes specific structural changes during the progression from human colon adenoma to carcinoma in vitro

  Gordon C. Jayson;Malcolm Lyon;Christos Paraskeva;Jeremy E. Turnbull

  177
  Citations

• Highly sensitive sequencing of the sulfated domains of heparan sulfate.

  Catherine L.R. Merry;Malcolm Lyon;Jon A. Deakin;John J. Hopwood

  160
  Citations

• Fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts.

  Maryse Delehedde;Malcolm Lyon;John T Gallagher;Philip S Rudland

  159
  Citations

• A new model for the domain structure of heparan sulfate based on the novel specificity of K5 lyase.

  Kevin J. Murphy;Catherine L.R. Merry;Malcolm Lyon;James E. Thompson

  157
  Citations

• Patterns of sulphation in heparan sulphate: polymorphism based on a common structural theme.

  John T Gallagher;Jeremy E Turnbull;Malcolm Lyon

  150
  Citations

• A simplified and sensitive fluorescent method for disaccharide analysis of both heparan sulfate and chondroitin/dermatan sulfates from biological samples

  Jon A Deakin;Malcolm Lyon

  129
  Citations

• Molecular cloning of the major cell surface heparan sulfate proteoglycan from rat liver.

  Andrew Pierce;Malcolm Lyon;Ian N Hampson;Graham J Cowling

  128
  Citations