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Chemistry

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65
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17481
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7576
National Ranking
438

Biology and Biochemistry

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65
Citations
17594
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9052
National Ranking
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Overview

Timothy D. H. Bugg is a researcher affiliated with the University of Warwick in the United Kingdom. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Engineering, with notable contributions to Biomedical Engineering, Biotechnology, Molecular Biology, Plant Science, and Inorganic Chemistry.

Their research focuses extensively on topics such as lignin and wood chemistry, biochemical and biochemical processes, biofuel production and bioconversion, enzyme-mediated dye degradation, microbial metabolic engineering and bioproduction, metal-catalyzed oxygenation mechanisms, and microbial bioremediation and biosurfactants.

Among their recent published papers are:

  • Bacterial enzymes for lignin depolymerisation: new biocatalysts for generation of renewable chemicals from biomass, 2020, Current Opinion in Chemical Biology
  • Metabolic engineering of Rhodococcus jostii RHA1 for production of pyridine-dicarboxylic acids from lignin, 2021, Microbial Cell Factories
  • Pharmaceutical applications of lignin-derived chemicals and lignin-based materials: linking lignin source and processing with clinical indication, 2023, Biomass Conversion and Biorefinery
  • Functional genomic analysis of bacterial lignin degraders: diversity in mechanisms of lignin oxidation and metabolism, 2020, Applied Microbiology and Biotechnology
  • Enhanced biocatalytic degradation of lignin using combinations of lignin-degrading enzymes and accessory enzymes, 2021, Catalysis Science & Technology

Frequent collaborators include Goran M. M. Rashid, Mussa Quareshy, Muralidharan Shanmugam, Alexander D. Cameron, and Yin Chen.

The researcher has contributed to publications in several venues, with multiple works appearing in Methods in enzymology on CD-ROM/Methods in enzymology, Bioresource Technology Reports, Biophysical Journal, Applied Microbiology and Biotechnology, and Bioresource Technology.

Best Publications

  • Pathways for degradation of lignin in bacteria and fungi

    Timothy D. H. Bugg;Mark Ahmad;Elizabeth M. Hardiman;Rahman Rahmanpour

  • The emerging role for bacteria in lignin degradation and bio-product formation

    Timothy D H Bugg;Mark Ahmad;Elizabeth M Hardiman;Rahul Singh

  • Molecular basis for vancomycin resistance in Enterococcus faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA.

    Timothy D. H. Bugg;Gerard D. Wright;Sylvie Dutka-Malen;Michel Arthur

  • Lignocellulose degradation mechanisms across the Tree of Life.

    Simon M. Cragg;Gregg T. Beckham;Neil C. Bruce;Timothy D. H. Bugg

  • The biosynthesis of peptidoglycan lipid‐linked intermediates

    Ahmed Bouhss;Amy E. Trunkfield;Timothy D.H. Bugg;Dominique Mengin-Lecreulx

  • Identification of DypB from Rhodococcus jostii RHA1 as a lignin peroxidase.

    Mark Ahmad;Joseph N. Roberts;Elizabeth M. Hardiman;Rahul Singh

  • Dioxygenase enzymes: catalytic mechanisms and chemical models

    Timothy D.H. Bugg

  • Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota

    Yijun Zhu;Eleanor Jameson;Marialuisa Crosatti;Hendrik Schäfer

  • Development of novel assays for lignin degradation: comparative analysis of bacterial and fungal lignin degraders

    Mark Ahmad;Charles R. Taylor;David Pink;Kerry Burton

  • Antimicrobial nucleoside antibiotics targeting cell wall assembly: Recent advances in structure–function studies and nucleoside biosynthesis

    Michael Winn;Rebecca J. M. Goss;Ken-ichi Kimura;Timothy D. H. Bugg

  • Identification of vancomycin resistance protein VanA as a D-alanine : D-alanine ligase of altered substrate specificity

    Timothy D. H. Bugg;Sylvie Dutka-Malen;Michel Arthur;Patrice Courvalin

  • Bacterial cell wall assembly: still an attractive antibacterial target

    Timothy D.H. Bugg;Darren Braddick;Christopher G. Dowson;David I. Roper

  • Does abscisic acid affect strigolactone biosynthesis

    Juan A. López-Ráez;Juan A. López-Ráez;Wouter Kohlen;Tatsiana Charnikhova;Patrick Mulder

  • Breaking Down Lignin to High-Value Chemicals: The Conversion of Lignocellulose to Vanillin in a Gene Deletion Mutant of Rhodococcus jostii RHA1

    Paul D. Sainsbury;Elizabeth M. Hardiman;Mark Ahmad;Hiroshi Otani

  • Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis.

    Ken-ichi Kimura;Timothy D. H. Bugg

  • Modes of action of tunicamycin, liposidomycin B, and mureidomycin A: inhibition of phospho-N-acetylmuramyl-pentapeptide translocase from Escherichia coli.

    Philip E. Brandish;Ken Ichi Kimura;Masatoshi Inukai;Robert Southgate

  • Enzymatic conversion of lignin into renewable chemicals

    Timothy D H Bugg;Rahman Rahmanpour

  • Non-heme iron-dependent dioxygenases: unravelling catalytic mechanisms for complex enzymatic oxidations

    Timothy D H Bugg;S Ramaswamy

  • Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria

    Jean-Luc Mainardi;Régis Villet;Régis Villet;Régis Villet;Timothy D. Bugg;Claudine Mayer;Claudine Mayer;Claudine Mayer

  • Arene cis-dihydrodiol formation: from biology to application

    Derek R. Boyd;Timothy D. H. Bugg

Frequent Co-Authors

Christopher G. Dowson
Christopher G. Dowson University of Warwick
Andrew J. Thompson
Andrew J. Thompson Cranfield University
Gillian Reid
Gillian Reid University of Southampton
Lindsay D. Eltis
Lindsay D. Eltis University of British Columbia
Roger C. Levesque
Roger C. Levesque Université Laval
Stephen D. Evans
Stephen D. Evans University of Leeds
Michel Arthur
Michel Arthur Centre de Recherche des Cordeliers
Derek R. Boyd
Derek R. Boyd Queen's University Belfast
Alexander D. Cameron
Alexander D. Cameron University of Warwick
Richard J. Bushby
Richard J. Bushby University of Leeds

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