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Sergei Y. Noskov

Sergei Y. Noskov

D-Index & Metrics

Chemistry

D-Index
45
Citations
7356
World Ranking
16448
National Ranking
441

Overview

Sergei Y. Noskov was affiliated with the University of Calgary in Canada. Their work spanned various aspects of biochemistry, genetics, molecular biology, and medicine, with a strong focus on molecular biology and cardiology.

Their research contributions primarily addressed topics including:

  • Ion channel regulation and function
  • Cardiac electrophysiology and arrhythmias
  • Lipid membrane structure and behavior
  • Ion transport and channel regulation
  • Mitochondrial function and pathology
  • Computational drug discovery methods
  • Receptor mechanisms and signaling

Sergei Y. Noskov published extensively in several scientific journals. The most frequent publication venues were:

  • Biophysical Journal (19 publications)
  • Clinical Pharmacology in Drug Development (4 publications)
  • Proceedings of the National Academy of Sciences (3 publications)
  • Nature Communications (3 publications)
  • Journal of Chemical Information and Modeling (3 publications)

Some of their recent papers included:

  • A Computational Pipeline to Predict Cardiotoxicity (2020), published in Circulation Research
  • Selectivity filter modalities and rapid inactivation of the hERG1 channel (2020), published in Proceedings of the National Academy of Sciences
  • Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE (2021), published in Nature Communications
  • Identification of PUFA interaction sites on the cardiac potassium channel KCNQ1 (2021), published in The Journal of General Physiology
  • Polarization Effects in Water-Mediated Selective Cation Transport across a Narrow Transmembrane Channel (2021), published in Journal of Chemical Theory and Computation

The scientist collaborated frequently with several co-authors throughout their career, including:

  • Hristina R. Zhekova (14 collaborations)
  • Hanif M. Khan (11 collaborations)
  • Williams E. Miranda (10 collaborations)
  • Alexander Pushkin (10 collaborations)
  • Ira Kurtz (10 collaborations)

Sergei Y. Noskov's research addressed key questions in ion channel function and cardiac physiology, utilizing a multidisciplinary approach that combined experimental and computational methods. Their work contributed insights into the molecular mechanisms underlying ion transport, channel regulation, and cardiac electrophysiological processes.

Best Publications

  • Control of ion selectivity in potassium channels by electrostatic and dynamic properties of carbonyl ligands

    Sergei Yu Noskov;Simon Bernèche;Benoît Roux

  • Emerging Diversity in Lipid–Protein Interactions

    Valentina Corradi;Besian I. Sejdiu;Haydee Mesa-Galloso;Haleh Abdizadeh

  • Molecular Dynamics Study of Hydration in Ethanol−Water Mixtures Using a Polarizable Force Field†

    Sergei Yu. Noskov;Guillaume Lamoureux;Benoit Roux

  • Ion Permeation through the α-Hemolysin Channel: Theoretical Studies Based on Brownian Dynamics and Poisson-Nernst-Plank Electrodiffusion Theory

    Sergei Yu. Noskov;Wonpil Im;Benoît Roux

  • Ion selectivity in potassium channels.

    Sergei Yu. Noskov;Benoît Roux

  • Importance of Hydration and Dynamics on the Selectivity of the KcsA and NaK Channels

    Sergei Yu. Noskov;Benoît Roux

  • Control of ion selectivity in LeuT: two Na+ binding sites with two different mechanisms.

    Sergei Y. Noskov;Benoît Roux

  • Atomic Level Anisotropy in the Electrostatic Modeling of Lone Pairs for a Polarizable Force Field Based on the Classical Drude Oscillator

    Edward Harder;Victor M. Anisimov;Igor V. Vorobyov;Pedro E. M. Lopes

  • Ion selectivity in channels and transporters

    Benoît Roux;Simon Bernèche;Bernhard Egwolf;Bogdan Lev

  • Representation of Ion–Protein Interactions Using the Drude Polarizable Force-Field

    Hui Li;Van Ngo;Mauricio Chagas Da Silva;Dennis R. Salahub

  • Representation of Ion–Protein Interactions Using the Drude Polarizable Force-Field

    Hui Li;Van Ngo;Mauricio Chagas Da Silva;Dennis R. Salahub

  • Free energy decomposition of protein-protein interactions.

    Sergey Yu. Noskov;Carmay Lim;Carmay Lim

  • Identification of Novel Cholesterol-binding Regions in Kir2 Channels

    Avia Rosenhouse-Dantsker;Sergei Noskov;Serdar Durdagi;Diomedes E. Logothetis

  • Two mechanisms of ion selectivity in protein binding sites

    Haibo Yu;Sergei Yu. Noskov;Benoît Roux

  • Ion-Controlled Conformational Dynamics in the Outward-Open Transition from an Occluded State of LeuT

    Chunfeng Zhao;Sebastian Stolzenberg;Luis Gracia;Harel Weinstein

  • Combined Receptor and Ligand-Based Approach to the Universal Pharmacophore Model Development for Studies of Drug Blockade to the hERG1 Pore Domain

    Serdar Durdagi;Henry J. Duff;Sergei Yu . Noskov

  • Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model

    H. Peter Larsson;Xiaoyu Wang;Bogdan Lev;Isabelle Baconguis

  • The RCK2 Domain Uses a Coordination Site Present in Kir Channels to Confer Sodium Sensitivity to Slo2.2 Channels

    Zhe Zhang;Avia Rosenhouse-Dantsker;Qiong Yao Tang;Sergei Noskov

  • Modeling of open, closed, and open-inactivated states of the hERG1 channel: structural mechanisms of the state-dependent drug binding.

    Serdar Durdagi;Sumukh Deshpande;Henry J. Duff;Sergei Yu Noskov

  • A Computational Pipeline to Predict Cardiotoxicity: From the Atom to the Rhythm.

    Pei Chi Yang;Kevin R. Demarco;Parya Aghasafari;Mao Tsuen Jeng

  • Hydrophobic plug functions as a gate in voltage-gated proton channels

    Adam Chamberlin;Feng Qiu;Santiago Rebolledo;Yibo Wang

  • ATP transport through VDAC and the VDAC-tubulin complex probed by equilibrium and nonequilibrium MD simulations.

    Sergei Yu. Noskov;Tatiana K. Rostovtseva;Sergey M. Bezrukov

Frequent Co-Authors

Benoît Roux
Benoît Roux University of Chicago
Sergey M. Bezrukov
Sergey M. Bezrukov National Institutes of Health
D. Peter Tieleman
D. Peter Tieleman University of Calgary
Ira Kurtz
Ira Kurtz University of California, Los Angeles
Lei Shi
Lei Shi National Institute on Drug Abuse
Diomedes E. Logothetis
Diomedes E. Logothetis Northeastern University
Harel Weinstein
Harel Weinstein Cornell University
Z. Hong Zhou
Z. Hong Zhou University of California, Los Angeles

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