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Fulvio Ursini

Fulvio Ursini

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Biology and Biochemistry
Italy
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
83
Citations
28850
World Ranking
3462
National Ranking
67

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Italy Leader Award

Overview

Fulvio Ursini is affiliated with the University of Padua in Italy and has contributed extensively to research in biochemistry, genetics, and molecular biology. Their work spans multiple disciplines including nursing and medicine, with a notable focus on molecular biology and nutrition and dietetics.

The scientist has published numerous papers, with a strong presence in specialized journals related to oxidative stress and redox biology. Key recent publications by Ursini include:

  • Lipid peroxidation and ferroptosis: The role of GSH and GPx4, 2020, Free Radical Biology and Medicine
  • A white paper on Phospholipid Hydroperoxide Glutathione Peroxidase (GPx4) forty years later, 2022, Free Radical Biology and Medicine

Ursini's frequent co-authors reflect collaborative efforts in the field and include Matilde Maiorino, Giovanni Miotto, Antonella Roveri, Giorgio Cozza, and Qing Cheng. These collaborations have contributed to a substantial body of research advancing understanding in redox biology and related biochemical processes.

The main topics covered by Ursini involve selenium in biological systems, redox biology and oxidative stress, and trace elements in health. Additional thematic areas researched include ferroptosis and cancer prognosis, epigenetics and DNA methylation, genomics, phytochemicals and oxidative stress, and the role of free radicals and antioxidants.

Ursini's research is frequently published in journals such as:

  • Free Radical Biology and Medicine
  • Redox Biology
  • Antioxidants
  • IUBMB Life
  • Nature Communications

Their work contributes to understanding cellular processes like ferroptosis, an iron-dependent form of regulated cell death, with implications for cancer research and therapeutic approaches. With multiple papers analyzing glutathione peroxidase 4 (GPx4) and related enzymatic systems, Ursini's research informs biochemical pathways influencing oxidative damage and cellular defense mechanisms.

In terms of scientific fields, the primary focus lies in biochemistry, genetics, molecular biology, and nursing, supported by research outputs also relevant to medicine. Subfields of molecular biology, nutrition, pulmonary and respiratory medicine, biochemistry, and cancer research are integral to Ursini's scholarly profile.

Best Publications

  • Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

    Irina Ingold;Carsten Berndt;Sabine Schmitt;Sebastian Doll

  • The selenoenzyme phospholipid hydroperoxide glutathione peroxidase.

    Fulvio Ursini;Matilde Maiorino;Carlo Gregolin

  • Lipid peroxidation and ferroptosis: The role of GSH and GPx4.

    Fulvio Ursini;Matilde Maiorino

  • Dual Function of the Selenoprotein PHGPx During Sperm Maturation

    Fulvio Ursini;Sabina Heim;Michael Kiess;Matilde Maiorino

  • Diversity of glutathione peroxidases.

    F Ursini;M Maiorino;R Brigelius-Flohé;K D Aumann

  • Signaling Functions of Reactive Oxygen Species

    Henry Jay Forman;Matilde Maiorino;Fulvio Ursini

  • Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides.

    Fulvio Ursini;Matilde Maiorino;M. Valente;L. Ferri

  • How do nutritional antioxidants really work: nucleophilic tone and para-hormesis versus free radical scavenging in vivo.

    Henry Jay Forman;Kelvin J. A. Davies;Fulvio Ursini

  • Insight into the mechanism of ferroptosis inhibition by ferrostatin-1.

    Giovanni Miotto;Monica Rossetto;Maria Luisa Di Paolo;Laura Orian

  • Protective action of phospholipid hydroperoxide glutathione peroxidase against membrane-damaging lipid peroxidation. In situ reduction of phospholipid and cholesterol hydroperoxides.

    J P Thomas;M Maiorino;F Ursini;A W Girotti

  • The role of selenium peroxidases in the protection against oxidative damage of membranes

    Fulvio Ursini;Alberto Bindoli

  • Phospholipid hydroperoxide glutathione peroxidase.

    Matilde Maiorino;Carlo Gregolin;Fulvio Ursini

  • GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues.

    Matilde Maiorino;Marcus Conrad;Fulvio Ursini

  • Catalytic mechanisms and specificities of glutathione peroxidases: Variations of a basic scheme

    Stefano Toppo;Leopold Flohé;Fulvio Ursini;Stefano Vanin

  • Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoproteins to oxidative modification.

    A Bonanome;A Pagnan;S Biffanti;A Opportuno

  • Formation of alpha-tocopherol radical and recycling of alpha-tocopherol by ascorbate during peroxidation of phosphatidylcholine liposomes. An electron paramagnetic resonance study.

    Marina Scarpa;Adelio Rigo;Matilde Maiorino;Fulvio Ursini

  • Redox homeostasis: The Golden Mean of healthy living

    Fulvio Ursini;Matilde Maiorino;Henry Jay Forman

  • Male Fertility Is Linked to the Selenoprotein Phospholipid Hydroperoxide Glutathione Peroxidase

    Carlo Foresta;Leopold Flohé;Andrea Garolla;Antonella Roveri

  • Mitochondrial glutathione peroxidase 4 disruption causes male infertility

    Manuela Schneider;Heidi Förster;Auke Boersma;Alexander Seiler

  • The Nuclear Form of Phospholipid Hydroperoxide Glutathione Peroxidase Is a Protein Thiol Peroxidase Contributing to Sperm Chromatin Stability

    M. Conrad;S. G. Moreno;F. Sinowatz;F. Ursini

Frequent Co-Authors

Matilde Maiorino
Matilde Maiorino University of Padua
Leopold Flohé
Leopold Flohé University of Padua
Henry Jay Forman
Henry Jay Forman University of Southern California
Alex Sevanian
Alex Sevanian University of Southern California
Marcus Conrad
Marcus Conrad Helmholtz Zentrum München
Paolo G. Camici
Paolo G. Camici Vita-Salute San Raffaele University
Kelvin J.A. Davies
Kelvin J.A. Davies University of Southern California
Silvio C. E. Tosatto
Silvio C. E. Tosatto University of Padua
Regina Brigelius-Flohé
Regina Brigelius-Flohé University of Potsdam
Carlo Foresta
Carlo Foresta University of Padua

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