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Christopher A. O’Callaghan

Christopher A. O’Callaghan

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
18379
World Ranking
18538
National Ranking
1451

Overview

Christopher A. O'Callaghan is affiliated with the University of Oxford in the United Kingdom. Their research primarily focuses on the field of Medicine, with significant contributions across several subfields including Molecular Biology, Immunology, Nephrology, Epidemiology, and Economics and Econometrics.

The scientist's recent publications illustrate a range of interests within medical research. Key papers include:

  • Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling (2021, Cell Reports)
  • Impact of the COVID-19 pandemic on emergency department attendances and acute medical admissions (2021, BMC Emergency Medicine)
  • Prevalence of chronic kidney disease in the community using data from OxRen: a UK population-based cohort study (2020, British Journal of General Practice)
  • Prevalence and factors associated with multimorbidity among primary care patients with decreased renal function (2021, PLoS ONE)
  • Process of care and activity in a clinically inclusive ambulatory emergency care unit: progressive effect over time on clinical outcomes and acute medical admissions (2020, Future Healthcare Journal)

Frequent co-authors collaborating with O'Callaghan include:

  • Michael E. Reschen
  • Richard Hobbs
  • Thomas K. Hiron
  • Daniel Lasserson
  • Jiahao Jiang

O'Callaghan's work often appears in notable publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • British Journal of General Practice
  • PLoS ONE
  • Future Healthcare Journal
  • Applied Microbiology and Biotechnology

The main topics addressed within their research include:

  • Chronic Disease Management Strategies
  • Dialysis and Renal Disease Management
  • Immune cells in cancer
  • Chronic Kidney Disease and Diabetes
  • Health Systems, Economic Evaluations, Quality of Life
  • Atherosclerosis and Cardiovascular Diseases
  • Immune Cell Function and Interaction

Best Publications

  • Global Prevalence of Chronic Kidney Disease - A Systematic Review and Meta-Analysis.

    Nathan R. Hill;Samuel T. Fatoba;Jason L. Oke;Jennifer A. Hirst

  • HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

    Veronique M. Braud;David S. J. Allan;Christopher A. O'Callaghan;Kalle Söderström

  • Direct Visualization of Antigen-specific CD8+T Cells during the Primary Immune Response to Epstein-Barr Virus In Vivo

    M.F.C. Callan;L. Tan;N. Annels;G.S. Ogg

  • Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules.

    Marco Colonna;Jacqueline Samaridis;Marina Cella;Lena Angman

  • A Re-Evaluation of the Frequency of CD8+ T Cells Specific for EBV in Healthy Virus Carriers

    Linda C. Tan;Nancy Gudgeon;Nicola E. Annels;Pokrath Hansasuta

  • Functional Heterogeneity and High Frequencies of Cytomegalovirus-Specific CD8+ T Lymphocytes in Healthy Seropositive Donors

    Geraldine M. A. Gillespie;Mark R. Wills;Victor Appay;Chris O'Callaghan

  • Production of soluble alphabeta T-cell receptor heterodimers suitable for biophysical analysis of ligand binding.

    B E Willcox;G F Gao;Wyer;C A O'Callaghan

  • Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes

    Annette Oxenius;David A. Price;Philippa J. Easterbrook;Christopher A. O'Callaghan

  • Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

    Kyle J Gaulton;Kyle J Gaulton;Teresa Ferreira;Yeji Lee;Anne Raimondo

  • A New Look at T Cells

    Andrew J. McMichael;Christopher A. O'Callaghan

  • Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure.

    Rachel L. Allen;Chris A. O’Callaghan;Andrew J. McMichael;Paul Bowness

  • Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors.

    E J Lepin;J M Bastin;D S Allan;G Roncador

  • Structure and function of the human MHC class Ib molecules HLA-E, HLA-F and HLA-G

    Christopher A. O'Callaghan;John I. Bell

  • Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E

    C A O'Callaghan;J Tormo;B E Willcox;B E Willcox;V M Braud

  • Recognition and Blocking of Innate Immunity Cells by Candida albicans Chitin

    Héctor M. Mora-Montes;Mihai G. Netea;Gerben Ferwerda;Megan D. Lenardon

  • A genetics-led approach defines the drug target landscape of 30 immune-related traits

    H Fang;H De Wolf;B Knezevic;K L Burnham

  • Regulation of ligands for the activating receptor NKG2D

    Anita R. Mistry;Chris A. O'Callaghan

  • Oligoclonal Expansions of CD8+ T Cells in Chronic HIV Infection Are Antigen Specific

    Jamie D.K. Wilson;Graham S. Ogg;Rachel L. Allen;Philip J.R. Goulder

  • Structure of the Fungal Beta-Glucan-Binding Immune Receptor Dectin-1: Implications for Function.

    J. Brown;C.A. O'Callaghan;A.S.J. Marshall;R.J.C. Gilbert

  • Functionally Inert HIV-Specific Cytotoxic T Lymphocytes Do Not Play a Major Role in Chronically Infected Adults and Children

    Philip J.R. Goulder;Philip J.R. Goulder;Yanhua Tang;Christian Brander;Michael R. Betts

Frequent Co-Authors

Andrew J. McMichael
Andrew J. McMichael University of Oxford
John I. Bell
John I. Bell Ellison Institute of Technology
E Y Jones
E Y Jones University of Oxford
Graham S. Ogg
Graham S. Ogg University of Oxford
Bent K. Jakobsen
Bent K. Jakobsen Continuum Life Sciences
Karl Harlos
Karl Harlos University of Oxford
David I. Stuart
David I. Stuart University of Oxford
Philip J. R. Goulder
Philip J. R. Goulder University of Oxford
Steve P. Watson
Steve P. Watson University of Birmingham
Richard J. Cornall
Richard J. Cornall University of Oxford

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