World's Best Scientists 2026 revealed!
Maria Trojanowska

Maria Trojanowska

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
14495
World Ranking
5446
National Ranking
2583

Medicine

D-Index
74
Citations
14978
World Ranking
19515
National Ranking
9714

Overview

Maria Trojanowska is affiliated with Boston University in the United States and has a research focus primarily within the field of Medicine, with 62 publications listed under this category. Their work spans several important subfields including Pathology and Forensic Medicine, Rheumatology, Pulmonary and Respiratory Medicine, Immunology, and Molecular Biology.

The scientist's research topics include:

  • Systemic Sclerosis and Related Diseases
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Rheumatoid Arthritis Research and Therapies
  • Osteoarthritis Treatment and Mechanisms
  • Connective Tissue Growth Factor Research
  • Mast cells and histamine
  • Dermatologic Treatments and Research

Key recent publications illustrate the scope of their work:

  • "Lung injury-induced activated endothelial cell states persist in aging-associated progressive fibrosis," 2024, Nature Communications
  • "Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis," 2022, Nature Communications
  • "Innate Immune Modulation Induced by EBV Lytic Infection Promotes Endothelial Cell Inflammation and Vascular Injury in Scleroderma," 2021, Frontiers in Immunology
  • "The role of the oncostatin M/OSM receptor β axis in activating dermal microvascular endothelial cells in systemic sclerosis," 2020, Arthritis Research & Therapy
  • "Fli1 Downregulation in Scleroderma Myeloid Cells Has Profibrotic and Proinflammatory Effects," 2020, Frontiers in Immunology

Trojanowska frequently publishes in journals such as Arthritis & Rheumatology, Arthritis Research & Therapy, Nature Communications, Research Square, and Frontiers in Immunology. The count of publications in these venues shows significant contributions, especially with 14 papers in Arthritis & Rheumatology and four in Arthritis Research & Therapy.

Collaborations are a notable aspect of their career. Frequent co-authors include:

  • Andreea M. Bujor
  • Monique Hinchcliff
  • Daniel H. Solomon
  • Richard Bucala
  • New Haven

These collaborations indicate a broad network across several researchers with shared interests in related biomedical fields. Trojanowska's research emphasizes vascular and fibrotic processes associated with systemic sclerosis and related connective tissue disorders, contributing to a deeper understanding of the mechanisms underlying these complex diseases.

Best Publications

  • Proteome-wide Analysis and CXCL4 as a Biomarker in Systemic Sclerosis

    L. Van Bon;L. Van Bon;A. J. Affandi;A. J. Affandi;J. Broen;J. Broen;R. B. Christmann

  • Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3

    Shu Jen Chen;Weihua Yuan;Yasuji Mori;Anait Levenson

  • Ets proteins in biological control and cancer

    Tien Hsu;Maria Trojanowska;Dennis K. Watson

  • Pathogenesis of systemic sclerosis: recent insights of molecular and cellular mechanisms and therapeutic opportunities:

    John Varga;Maria Trojanowska;Masataka Kuwana

  • Increased Expression of TGF-β Receptors by Scleroderma Fibroblasts: Evidence for Contribution of Autocrine TGF-β Signaling to Scleroderma Phenotype

    Tamihiro Kawakami;Hironobu Ihn;Weidong Xu;Edwin Smith

  • A strategy for determining the pathogenesis of systemic sclerosis. Is transforming growth factor beta the answer

    Leroy Ec;Smith Ea;Kahaleh Mb;Trojanowska M

  • Role of PDGF in fibrotic diseases and systemic sclerosis

    M. Trojanowska

  • Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.

    A Yamakage;K Kikuchi;E A Smith;E C LeRoy

  • TGF-β and CTGF have overlapping and distinct fibrogenic effects on human renal cells

    Elizabeth Gore-Hyer;Daniel Shegogue;Malgorzata Markiewicz;Shianlen Lo

  • Pathogenesis of fibrosis: type 1 collagen and the skin.

    M Trojanowska;E C LeRoy;B Eckes;T Krieg

  • Transforming Growth Factor-β Receptor Type I-dependent Fibrogenic Gene Program Is Mediated via Activation of Smad1 and ERK1/2 Pathways

    Jaspreet Pannu;Sashidhar Nakerakanti;Edwin Smith;Peter ten Dijke

  • Cellular and molecular aspects of vascular dysfunction in systemic sclerosis

    Maria Trojanowska

  • Interaction of Smad3 with a proximal smad-binding element of the human α2(I) procollagen gene promoter required for transcriptional activation by TGF-β

    Shu Jen Chen;Weihua Yuan;Sientay Lo;Maria Trojanowska

  • Elevated levels of platelet derived growth factor and transforming growth factor-beta 1 in bronchoalveolar lavage fluid from patients with scleroderma.

    Ludwicka A;Ohba T;Trojanowska M;Yamakage A

  • Transcriptional Regulation of the Human α2(I) Collagen Gene COMBINED ACTION OF UPSTREAM STIMULATORY AND INHIBITORY CIS-ACTING ELEMENTS

    Hironobu Ihn;Kazunori Ohnishi;Takeshi Tamaki;E. Carwile LeRoy

  • Endothelial Fli1 Deficiency Impairs Vascular Homeostasis : A Role in Scleroderma Vasculopathy

    Yoshihide Asano;Lukasz Stawski;Faye Hant;Kristin Highland

  • Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-β and mediates TIMP-1 up-regulation

    Masayoshi Yamanaka;Daniel Shegogue;Heuping Pei;Shizhong Bu

  • Fli-1 inhibits collagen type I production in dermal fibroblasts via an Sp1-dependent pathway.

    Joanna Czuwara-Ladykowska;Fumiaki Shirasaki;Pascale Jackers;Dennis K. Watson

  • Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts

    Humphrey Gardner;Jeffrey R. Shearstone;Raj Bandaru;Tom Crowell

  • Persistent Down-Regulation of Fli1, a Suppressor of Collagen Transcription, in Fibrotic Scleroderma Skin

    Masahide Kubo;Joanna Czuwara-Ladykowska;Omar Moussa;Margaret Markiewicz

Frequent Co-Authors

Yoshihide Asano
Yoshihide Asano University of Tokyo
Takashi Taniguchi
Takashi Taniguchi National Institute for Materials Science
Shinichi Sato
Shinichi Sato University of Tokyo
Robert Lafyatis
Robert Lafyatis University of Pittsburgh
Dennis K. Watson
Dennis K. Watson Medical University of South Carolina
Richard M. Silver
Richard M. Silver Medical University of South Carolina
John Varga
John Varga University of Michigan–Ann Arbor
Maureen D. Mayes
Maureen D. Mayes The University of Texas at Austin
Peter ten Dijke
Peter ten Dijke Leiden University Medical Center
Stefania Jablonska
Stefania Jablonska Institut Gustave Roussy

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